Patents by Inventor Beihui Liu

Beihui Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Promoter construct for gene expression in neuronal cells
    Patent number: 7341847
    Abstract: The invention relates to a chimeric promoter construct useful for neuronal cell specific gene expression. The invention provides a recombinant nucleic acid molecule that comprises a neuronal cell specific promoter such as platelet-derived growth factor ?-chain promoter, operably linked to a heterologous enhancer which enhances the transcriptional activity of the promoter, such as cytomegalovirus immediate early gene enhancer. The promoter construct according to the invention can increase and prolong gene expression in neuronal cells and may be advantageously used in gene therapy of neuronal disorders.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: March 11, 2008
    Assignee: Agency for Science, Technology and Research
    Inventors: Shu Wang, Beihui Liu, Xu Wang
  • Promoter construct for gene expression in neuronal cells
    Publication number: 20040197313
    Abstract: The invention relates to a chimeric promoter construct useful for neuronal cell specific gene expression. The invention provides a recombinant nucleic acid molecule that comprises a neuronal cell specific promoter such as platelet-derived growth factor &bgr;-chain promoter, operably linked to a heterologous enhancer which enhances the transcriptional activity of the promoter, such as cytomegalovirus immediate early gene enhancer. The promoter construct according to the invention can increase and prolong gene expression in neuronal cells and may be advantageously used in gene therapy of neuronal disorders.
    Type: Application
    Filed: April 2, 2003
    Publication date: October 7, 2004
    Applicant: Institute of Materials Research and Engineering
    Inventors: Shu Wang, Beihui Liu, Xu Wang