Abstract: A safe disposal machine for peritoneal dialysis liquid waste comprises a box main body, with ultraviolet lamps for box internal disinfection provided at the top of the box's interior, a weighing device for peritoneal dialysis liquid waste weighing provided at the top of a filter plate, a placing and cutting device for drainage bag cutting provided at the top of the weighing device, and a flushing and disinfection device for drainage bag disinfection provided in the box. The invention can weigh the drainage bag, facilitating the recording of the peritoneal dialysis ultrafiltration volume for patients; the placing and cutting device can take down the weighed drainage bag, and simultaneously cut the drainage bag into a cross shape to pull outwards; the drainage bag capable of inner-side turning over can facilitate the complete washing through flushing and disinfection device, to avoid the residual liquid waste endangering others and the environment.