Patents by Inventor Bela Kerekjarto

Bela Kerekjarto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzenesulfonamides and a process for their preparation
    Patent number: 5143937
    Abstract: Compounds of the formula I ##STR1## where R.sup.1 to R.sup.5 have the meaning indicated, a process for their preparation and their use as medicaments are described. They are effective lipid-lowering agents with antioxidative properties from the benzenesulfonamide series. They do not have hypotensive and diuretic properties.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: September 1, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Ernold Granzer, Bela Kerekjarto
  • 7(1H-pyrrol-3-YL)-substituted 3,5-dihydroxyhept-6-enoic acids, 7-(1H-pyrrol-3-YL)-substituted 3,5-dihyroxyhept-anoic acids, their corresponding delta-lactones and salts, their use as medicaments and pharmaceutical products and intermediates
    Patent number: 5055484
    Abstract: 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxyhept-6-enoic acids, 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxyheptanoic acids of the formula I ##STR1## in which A, B, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the indicated meanings, and the corresponding .delta.-lactones of the formula II ##STR2## processes for the preparation of these compounds, their use as medicaments and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formulae I and II are described.
    Type: Grant
    Filed: July 8, 1988
    Date of Patent: October 8, 1991
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heiner Jendralla, Gerhard Beck, Ekkehard Baader, Bela Kerekjarto
  • Pyridazine 3,5-dihydroxy carboxylic acids and derivatives thereof, the use thereof for hypercholesterolemia
    Patent number: 4946841
    Abstract: New 3,5-dihydroxy carboxylic acids and derivatives thereof, a process for the preparation thereof, the use thereof as pharmaceuticals, pharmaceutical products and intermediates 3,5-Dihydroxy carboxylic acids and derivatives thereof, of the formula I ##STR1## and the corresponding Lactones of the formula II ##STR2## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X-Y have the indicated meanings, a process for the preparation of these compounds, the use thereof as pharmaceuticals, and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formulae I and II are described.
    Type: Grant
    Filed: January 6, 1989
    Date of Patent: August 7, 1990
    Assignee: Hoechst Aktiengesellachaft
    Inventors: Ekkehard Baader, Heiner Jendralla, Bela Kerekjarto, Gerhard Beck
  • 4(R)-substituted 6(S)-phenoxymethyl-, 6(S)-.beta.-phenylethyl- and 6(S)-.beta.-styryl-tetrahydropyran-2-ones, a highly stereoselective process for their preparation, pharmaceutical products based on these compounds, and their use
    Patent number: 4946852
    Abstract: 4(R)-Substituted 6(S)-phenyloxymethyl-, 6(S)-.beta.-phenylethyl- and 6(S)-.beta.-styryl-tetrahydropyran-2-ones of the general formula V ##STR1## in which R.sup.7, R.sup.8 and A have the meanings given, and the corresponding open-chain hydroxycarboxylic acids, pharmacologically acceptable salts and esters thereof, processes for the preparation of these compounds, their use as medicaments and pharmaceutical products are described. Novel .alpha.,.beta.-unsaturated lactones for the preparation of the compounds of the formula V are also described.
    Type: Grant
    Filed: March 30, 1989
    Date of Patent: August 7, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heiner Jendralla, Gerhard Beck, Gunther Wess, Bela Kerekjarto
  • Benzenesulfonamide derivatives and a process for the preparation thereof
    Patent number: 4929643
    Abstract: Compounds of the formula I ##STR1## with R.sup.1 equal to H or (cyclo)alk(en)yl, R.sup.2 equal to H or alkyl, R.sup.3 equal to alkyl, R.sup.4 /R.sup.5 equal to H, alkyl or acyl, and Y equal to H, alkyl, CF.sub.3 or Hal, are described, as are processes for the preparation thereof.They are effective diuretics and antihypertensive agents with a lipid-lowering action.
    Type: Grant
    Filed: May 1, 1989
    Date of Patent: May 29, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Max Hropot, Ernold Granzer, Bela Kerekjarto
  • 3-Demethylmevalonic acid derivatives, a process for their preparation pharmaceutical products based on these compounds, their use and intermediates
    Patent number: 4914127
    Abstract: 3-Demethylmevalonic acid derivatives of the formula I (.delta.-lactone) and Ia (corresponding dihydroxycarboxylic acid derivative) ##STR1## in which A-B, Z, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the indicated meanings, a process for the preparation of these compounds, their use as medicaments and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I and Ia are described.
    Type: Grant
    Filed: March 8, 1989
    Date of Patent: April 3, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Beck, Bela Kerekjarto, Hans-Hermann Lau, Gunther Wess
  • Benzenesulfonamide derivatives and a process for the medical use thereof
    Patent number: 4849444
    Abstract: Compounds of the formula I ##STR1## with R.sup.1 equal to H or (cyclo)alk(en)yl, R.sup.2 equal to H or alkyl, R.sup.3 equal to alkyl, R.sup.4 /R.sup.5 equal to H, alkyl or acyl, and Y equal to H, alkyl, CF.sub.3 or Hal, are described, as are processes for the preparation thereof.They are effective diuretics and antihypertensive agents with a lipid-lowering action.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: July 18, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Max Hropot, Ernold Granzer, Bela Kerekjarto