Patents by Inventor Belle B. Liu

Belle B. Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for making and using polymorphs of cinacalcet
    Patent number: 8415501
    Abstract: The present invention is directed to methods and compositions for making and using a new polymorph of cinacalcet hydrochloride.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: April 9, 2013
    Assignee: Amgen, Inc.
    Inventors: Belle B. Liu, Pengzu Zhou, Nina Cauchon
  • SOLID-STATE FORM OF AMG 706 AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20100331548
    Abstract: The anti-angiogenic drug AMG 706 is provided in amorphous form. Also provided is AMG 706 drug substance wherein the AMG 706 is present, in at least a detectable amount, as amorphous AMG 706. Also provided is an AMG 706-crystallization inhibitor composite comprising particles of amorphous AMG 706 or a AMG 706 drug substance of the invention in intimate association with one or more crystallization inhibitors, for example polymers. Also provided is a pharmaceutical composition comprising such an AMG 706-crystallization inhibitor composite and one or more excipients. Also provided are processes for preparing amorphous AMG 706, AMG 706 drug substance of the invention, an AMG 706-crystallization inhibitor composite of the invention, and a pharmaceutical composition of the invention.
    Type: Application
    Filed: September 3, 2010
    Publication date: December 30, 2010
    Applicant: Amgen Inc.
    Inventors: Belle B. Liu, Gonzalo Alva, Nina Cauchon, Seshadri Neervannan, Pengzu Zhou
  • Solid-state form of AMG 706 and pharmaceutical compositions thereof
    Publication number: 20080108664
    Abstract: The anti-angiogenic drug AMG 706 is provided in amorphous form. Also provided is AMG 706 drug substance wherein the AMG 706 is present, in at least a detectable amount, as amorphous AMG 706. Also provided is an AMG 706-crystallization inhibitor composite comprising particles of amorphous AMG 706 or a AMG 706 drug substance of the invention in intimate association with one or more crystallization inhibitors, for example polymers. Also provided is a pharmaceutical composition comprising such an AMG 706-crystallization inhibitor composite and one or more excipients. Also provided are processes for preparing amorphous AMG 706, AMG 706 drug substance of the invention, an AMG 706-crystallization inhibitor composite of the invention, and a pharmaceutical composition of the invention.
    Type: Application
    Filed: December 7, 2006
    Publication date: May 8, 2008
    Inventors: Belle B. Liu, Gonzalo Alva, Nina Cauchon, Seshadri Neervannan, Pengzu Zhou