Abstract: A monitoring system embodying a monitoring system embodying a method of this invention for monitoring predetermined patients with mental and/or behavioral disorders by accessing, analyzing and monitoring their measured input through a plurality of sensors inherent in most personal mobile devices is provided. The measured input may represents values attributed to at least one physical behavior of the patient that is representative of a symptom of at least one mental/behavior health condition. The measured input can be used to establish a baseline and thresholds thereof that separates the at least one physical behavior into normative from ab-normative behavior for each predetermined patient.

Abstract: Controlled-specimen-sampling oral devices are described, implanted or inserted into an oral cavity, built onto a prosthetic tooth crown, a denture plate, braces, a dental implant, or the like. The devices are replaced as needed. The controlled specimen sampling may be passive, based on a dosage form, or electro-mechanically controlled, for a high-precision, intelligent, specimen sampling. Additionally, the controlled sampling may be any one of the following: sampling in accordance with a preprogrammed regimen, sampling at a controlled rate, delayed sampling, pulsatile sampling, chronotherapeutic sampling, closed-loop sampling, responsive to a sensor's input, sampling on demand from a personal extracorporeal system, sampling regimen specified by a personal extracorporeal system, sampling on demand from a monitoring center, via a personal extracorporeal system, and sampling regimen specified by a monitoring center, via a personal extracorporeal system.