Patents by Inventor Ben CAI

Ben CAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250304609
    Abstract: The present invention discloses a polymorphic form of a chalcone glycoside compound, and a preparation method and an application thereof in a medicament for treating a vascular disease. The chalcone glycoside compound has a structure of the general formula below or a hydrate thereof, where R1 and R2 are ?-D-glucosyl or ?-D-glucosyl; R3 is hydrogen or hydroxyl; and M is a metal ion, and n is 1-2. The chalcone glycoside compound described in the present invention can effectively inhibit platelet aggregation, has a protective effect against cell apoptosis, can significantly relieve ischemia/ischemia-reperfusion injury, increases a serum SOD content, and improves behavior disorders and tissue infarction focuses induced by ischemia-reperfusion. Moreover, this crystal form has a simple process, high purity and excellent stability, and has important significance for developing medicaments for treating vascular diseases with stronger therapeutic effects, lower toxicity and urgent clinical needs.
    Type: Application
    Filed: December 25, 2023
    Publication date: October 2, 2025
    Inventors: Ben CAI, Tianjian YE, Wei ZHANG, Guanzan JIANG, Jindan WANG, Min LU, Meijuan GUO, Shenjie PAN, Yongling CHEN, Wei HUANG, Zhuoqi XIE
  • Patent number: 9624254
    Abstract: A new pharmaceutically acceptable salt of hydroxysafflor yellow A as presented in formula (I), in particular new monomer compounds of potassium, ammonium, calcium, and magnesium salts of hydroxysafflor yellow A, preparation method therefor, and medical uses thereof are provided. Compared to hydroxysafflor yellow A, the hydroxysafflor yellow A pharmaceutical salts of the present invention have a purity of at least 98% and are monomer compounds that are safer, more effective, stable, and controllable. The salts have the effects against PAF- or ADP-induced platelet aggregation, and can be used in treating blood circulatory disorders such as platelet aggregation, coronary artery diseases, angina, and acute cerebral ischemia to the effect comparable to hydroxysafflor yellow A, wherein, n and M are defined as in the description.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: April 18, 2017
    Assignee: ZHEJIANG YONGNING PHARMACEUTICAL CO., LTD
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Patent number: 9243019
    Abstract: A hydroxysafflor yellow A sodium compound as shown in a formula (I) and preparation as well as medicinal application thereof are provided. According to the present invention, the safflower is utilized as a raw material. A monomer pharmaceutical compound, the hydroxysafflor yellow A sodium, is obtained by sufficient processes, and a purity thereof is surely above 98.5%. Therefore, the hydroxysafflor yellow A sodium is a monomer compound, which is safer, more effective, more stable and more controllable than hydroxysafflor yellow A, for treating blood circulation disorders such as platelet aggregation, coronary heart disease, angina pectoris and acute cerebral ischemia. Furthermore, the hydroxysafflor yellow A sodium has sufficient solubility and human tolerance.
    Type: Grant
    Filed: June 8, 2013
    Date of Patent: January 26, 2016
    Assignee: ZHEJIANG YONGNING PHARMACEUTICAL CO LTD
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Publication number: 20150197537
    Abstract: A new pharmaceutically acceptable salt of hydroxysafflor yellow A as presented in formula (I), in particular new monomer compounds of potassium, ammonium, calcium, and magnesium salts of hydroxysafflor yellow A, preparation method therefor, and medical uses thereof are provided. Compared to hydroxysafflor yellow A, the hydroxysafflor yellow A pharmaceutical salts of the present invention have a purity of at least 98% and are monomer compounds that are safer, more effective, stable, and controllable. The salts have the effects against PAF- or ADP-induced platelet aggregation, and can be used in treating blood circulatory disorders such as platelet aggregation, coronary artery diseases, angina, and acute cerebral ischemia to the effect comparable to hydroxysafflor yellow A, wherein, n and M are defined as in the description.
    Type: Application
    Filed: February 26, 2014
    Publication date: July 16, 2015
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Patent number: 8955101
    Abstract: The present disclosure discloses an upper-order computer, a lower-order computer, a monitoring system and a monitoring method, so as to eliminate the disadvantages of low standardization level and small scale in manually setting and adjusting performance parameters. The upper-order computer includes a central control module and an information interacting module, the information interacting module including a human-computer interacting unit, and the central control module including a processing unit, a display control unit and a parameter configuring unit, wherein the processing unit is adapted for controlling a lower-order computer by sending control commands; the display control unit is adapted for processing effective operating data acquired from the lower-order computer, and is adapted for instructing the human-computer interacting unit to perform presenting; and the parameter configuring unit is adapted for configuring parameters of the lower-order computer by sending parameter configuring commands.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: February 10, 2015
    Inventors: Yulin Su, Ben Cai, Rijun Huang
  • Publication number: 20150025030
    Abstract: A hydroxysafflor yellow A sodium compound as shown in a formula (I) and preparation as well as medicinal application thereof are provided. According to the present invention, the safflower is utilized as a raw material. A monomer pharmaceutical compound, the hydroxysafflor yellow A sodium, is obtained by sufficient processes, and a purity thereof is surely above 98.5%. Therefore, the hydroxysafflor yellow A sodium is a monomer compound, which is safer, more effective, more stable and more controllable than hydroxysafflor yellow A, for treating blood circulation disorders such as platelet aggregation, coronary heart disease, angina pectoris and acute cerebral ischemia. Furthermore, the hydroxysafflor yellow A sodium has sufficient solubility and human tolerance.
    Type: Application
    Filed: June 8, 2013
    Publication date: January 22, 2015
    Applicant: ZHEJIANG YONGNING PHARMACEUTICAL CO LTD
    Inventors: Fengqi Ye, Ben Cai, Min Lu, Yongling Chen
  • Patent number: 8868365
    Abstract: A system and a method of generating an external parameter value for a separately excited motor controller are disclosed, the system including: a digital signal processor to convert a received analog electrical signal into a digital signal and to scale the digital signal, so as to generate a parameter value in conformity with a data format of the system; an external parameter generating module to adjust the parameter value with a calibration coefficient to obtain the external parameter value; the calibration coefficient being generated by a calibration coefficient generating module and being pre-stored in a calibration coefficient storing module; and a calibration coefficient generating module to read the parameter value generated by the digital signal processor and obtain an actual measuring value as a reference parameter value, to calculate a difference value between the parameter value from the digital signal processor and the reference parameter value, and to generate the calibration coefficient from a rat
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: October 21, 2014
    Assignee: Liuzhou Wuling Motors Co., Ltd.
    Inventors: Rijun Huang, Yulin Su, Ben Cai, Yanzhang Ye
  • Patent number: 8689915
    Abstract: The present invention provides a heat dissipating system for an electric vehicle drive controller. The heat dissipating system for electric vehicle drive controller includes: high power MOS transistors for controlling magnitude of power supplied to an electric vehicle drive motor and for switching current direction, and a radiator connected to bodies of the MOS transistors, the radiator being made of aluminum alloy material, and a surface of the radiator being plated with a metallic nickel layer. Compared with existing electric vehicle drive controller, the electric vehicle drive controller of the present invention has advantages of low operating temperature, high reliability and long service life.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: April 8, 2014
    Assignee: Liuzhou Wuling Motors Co., Ltd.
    Inventors: Yanzhang Ye, Ben Cai, Rijun Huang, Libin Wei, Zhong Zheng
  • Publication number: 20120272312
    Abstract: The present disclosure discloses an upper-order computer, a lower-order computer, a monitoring system and a monitoring method, so as to eliminate the disadvantages of low standardization level and small scale in manually setting and adjusting performance parameters. The upper-order computer includes a central control module and an information interacting module, the information interacting module including a human-computer interacting unit, and the central control module including a processing unit, a display control unit and a parameter configuring unit, wherein the processing unit is adapted for controlling a lower-order computer by sending control commands; the display control unit is adapted for processing effective operating data acquired from the lower-order computer, and is adapted for instructing the human-computer interacting unit to perform presenting; and the parameter configuring unit is adapted for configuring parameters of the lower-order computer by sending parameter configuring commands.
    Type: Application
    Filed: July 15, 2011
    Publication date: October 25, 2012
    Applicant: LIUZHOU WULING MOTORS CO., LTD.
    Inventors: Yulin SU, Ben CAI, Rijun HUANG
  • Publication number: 20120130668
    Abstract: A system and a method of generating an external parameter value for a separately excited motor controller are disclosed, the system including: a digital signal processor to convert a received analog electrical signal into a digital signal and to scale the digital signal, so as to generate a parameter value in conformity with a data format of the system; an external parameter generating module to adjust the parameter value with a calibration coefficient to obtain the external parameter value; the calibration coefficient being generated by a calibration coefficient generating module and being pre-stored in a calibration coefficient storing module; and a calibration coefficient generating module to read the parameter value generated by the digital signal processor and obtain an actual measuring value as a reference parameter value, to calculate a difference value between the parameter value from the digital signal processor and the reference parameter value, and to generate the calibration coefficient from a rat
    Type: Application
    Filed: June 22, 2011
    Publication date: May 24, 2012
    Applicant: LIUZHOU WULING MOTORS CO., LTD.
    Inventors: Rijun HUANG, Yulin SU, Ben CAI, Yanzhang YE
  • Publication number: 20110297347
    Abstract: The present invention provides a heat dissipating system for an electric vehicle drive controller. The heat dissipating system for electric vehicle drive controller includes: high power MOS transistors for controlling magnitude of power supplied to an electric vehicle drive motor and for switching current direction, and a radiator connected to bodies of the MOS transistors, the radiator being made of aluminum alloy material, and a surface of the radiator being plated with a metallic nickel layer. Compared with existing electric vehicle drive controller, the electric vehicle drive controller of the present invention has advantages of low operating temperature, high reliability and long service life.
    Type: Application
    Filed: June 1, 2011
    Publication date: December 8, 2011
    Applicant: LIUZHOU WULING MOTORS CO., LTD.
    Inventors: Yanzhang YE, Ben CAI, Rijun HUANG, Libin WEI, Zhong ZHENG