Patents by Inventor Ben Gaston

Ben Gaston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HSD3B1 GENE AND 3BETA-HSD1 PROTEIN VARIANT DETECTION FOR DETERMINING CORTICOSTEROID RESPONSIVENESS
    Publication number: 20210032698
    Abstract: The present invention relates to methods, kits, and compositions for testing a sample from a subject with asthma to determine: i) if the subject is A/A or A/C at position 1245 in the HSD3B1 gene, and/or if the subject expresses a 367N version of the 3?-HSD1 protein (e.g., and should be administered a non-corticosteroid for their asthma), or ii) if the subject is C/C at position 1245 in the HSD3B1 gene, and/or if the subject expresses only the 367T version of the 3?-HSD1 protein (e.g., and should be administered a corticosteroid for their asthma). In certain embodiments, the corticosteroid is a glucocorticoid.
    Type: Application
    Filed: July 28, 2020
    Publication date: February 4, 2021
    Inventors: Nima Sharifi, Joe G. Zein, Ben Gaston