Abstract: A dialysis machine which monitors the pressure of blood entering and leaving a patient's body using several sensors (37, 39) and adapts the pressure of a dialysate solution feed to compensate for compliances in the dialysate fluid flow path. As a consequence, better flow balance is maintained throughout dialysis treatment leading to a more uniform removal of waste materials from the blood.

Abstract: A hemodialysis machine comprising a dialysate flow path for delivering a flow of dialysate solution through a dialyser, the flow path including a flow balancer for achieving a balance in the dialysate solution flow volume observed between an inlet and an outlet of the dialyser over the course of a treatment, the flow balancer comprising a first flow balance pump having an inlet valve and an outlet valve and a second flow balance pump having an inlet valve and an outlet valve, wherein the flow path further includes a flow restrictor means downstream of the flow balance pumps to reduce the pressure difference across the valves in the dialysate flow path.

Abstract: A hemodialysis machine including a main body and a door, the door being capable of opening and closing relative to the main body so as to receive and retain a disposable cartridge therebetween, the machine further including a controller and a pneumatic pump, the cartridge having a chassis with a platen side covered by a first deformable membrane and a door side covered by a second deformable membrane, the chassis and membranes defining a dialysate flow path for delivering a flow of dialysate solution through a dialyzer, the main body having a platen for in use sealing against the platen side of the cartridge and the door having an interface plate for in use sealing against the door side of the cartridge, the pneumatic pump being fluidically connected to an interface plate cavity between the interface plate and the cartridge by a pneumatic supply line, the pump being controlled by the controller to selectively generate a vacuum in the platen cavity so as to affix the cartridge to the door prior to operation of

Abstract: The invention covers a cartridge for use in a hemodialysis machine, the cartridge comprising a dialysate flow path including a dialyser, the dialysate flow path for delivering a flow of dialysate through the dialyser; a mixing pump defining a chamber having volume variable between a maximum volume and a minimum volume for receiving a predetermined volume of a first dialysate solution base, second dialysate solution base, and a volume of water; a first dialysate solution base supply conduit having a first positive displacement pump having a first inlet valve and a first outlet valve associated therewith; a second dialysate solution base supply conduit having a second positive displacement pump having a second inlet valve and a second outlet valve associated therewith; a first and second fluid conduit associated joining respective first and second positive displacement pumps with the mixing pump; and a third fluid conduit for connecting the mixing pump outlet to a dialyser filter inlet.

Abstract: A hemodialysis machine including a main body and a door, the door being capable of opening and closing relative to the main body so as to receive and retain a disposable cartridge therebetween, the machine further including a controller and a pneumatic pump, the cartridge having a chassis with a platen side covered by a first deformable membrane and a door side covered by a second deformable membrane, the chassis and membranes defining a dialysate flow path for delivering a flow of dialysate solution through a dialyser, the main body having a platen for in use sealing against the platen side of the cartridge and the door having an interface plate for in use sealing against the door side of the cartridge, the pneumatic pump being fluidically connected to an interface plate cavity between the interface plate and the cartridge by a pneumatic supply line, the pump being controlled by the controller to selectively generate a vacuum in the platen cavity so as to affix the cartridge to the door prior to operation of

Abstract: A hemodialysis machine comprising a dialysate flow path for delivering a flow of dialysate solution through a dialyser, the flow path including a flow balancer for achieving a balance in the dialysate solution flow volume observed between an inlet and an outlet of the dialyser over the course of a treatment, the flow balancer comprising a first flow balance pump having an inlet valve and an outlet valve and a second flow balance pump having an inlet valve and an outlet valve, wherein the flow path further includes a flow restrictor means downstream of the flow balance pumps to reduce the pressure difference across the valves in the dialysate flow path.

Abstract: The invention relates to a dialysis machine having improved flow balance. In particular, the invention monitors the pressure of blood entering and leaving a patient's body using several sensors (37, 39) and adapts the pressure of a dialysate solution feed to the dialysis machine to compensate for compliances in the fluid flow path. As a consequence, better flow balance is maintained throughout dialysis treatment leading to a more uniform removal of waste materials form the blood.