Patents by Inventor Ben Hindson

Ben Hindson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analysis of nucleic acids
    Patent number: 9127312
    Abstract: Provided herein are improved methods, compositions, and kits for analysis of nucleic acids. The improved methods, compositions, and kits can enable copy number estimation of a nucleic acid in a sample. Also provided herein are methods, compositions, and kits for determining the linkage of two or more copies of a target nucleic acid in a sample (e.g., whether the two or more copies are on the same chromosome or different chromosomes) or for phasing alleles.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: September 8, 2015
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: John Frederick Regan, Serge Saxonov, Mike Lucero, Ben Hindson, Phil Belgrader, Simant Dube, Austin So, Jeffrey Clark Mellen, Nicholas Jack Heredia, Kevin Ness, Bill Colston
  • COMPOSITIONS, METHODS AND SYSTEMS FOR POLYMERASE CHAIN REACTION ASSAYS
    Publication number: 20140302503
    Abstract: The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in polymerase chain reaction assays, such as droplet digital polymerase chain reaction (ddPCR) assays. The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in ddPCR assays using intercalating dyes. A dual surfactant system with at least one fluorosurfactant and at least one non-ionic non-fluorosurfactant may be employed for droplet generation and nucleic acid detection.
    Type: Application
    Filed: March 7, 2014
    Publication date: October 9, 2014
    Inventors: Adam Lowe, Geoff McDermott, Chris Hindson, Erin Chia, Amy Hiddessen, Ben Hindson, Chunxiao Han, Yaqi Wang
  • COMPOSITIONS, SYSTEMS AND METHODS FOR DROPLET FORMATION, SPACING AND DETECTION
    Publication number: 20140179544
    Abstract: The present disclosure provides assays and devices for forming, spacing, and/or detecting droplets. The droplets may be emulsions composed of two or more immiscible fluids. An emulsion can be a double emulsion, such as water-in-oil droplets that are present in a continuous aqueous phase. The double emulsion can be formed when the water-in-oil droplets are contacted with one or more streams of aqueous fluid(s). This disclosure also provides a variety of additives that can be added to the fluids.
    Type: Application
    Filed: September 6, 2013
    Publication date: June 26, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Erin Steenblock, Amy L. Hiddessen, Ben Hindson, Kevin Ness
  • Analysis of nucleic acids
    Publication number: 20120322058
    Abstract: Provided herein are improved methods, compositions, and kits for analysis of nucleic acids. The improved methods, compositions, and kits can enable copy number estimation of a nucleic acid in a sample. Also provided herein are methods, compositions, and kits for determining the linkage of two or more copies of a target nucleic acid in a sample (e.g., whether the two or more copies are on the same chromosome or different chromosomes) or for phasing alleles.
    Type: Application
    Filed: February 9, 2012
    Publication date: December 20, 2012
    Applicant: Bio-Rad Laboratories
    Inventors: John Frederick Regan, Serge Saxonov, Mike Lucero, Ben Hindson, Phil Belgrader, Simant Dube, Austin So, Jeffrey Clark Mellen, Nicholas Jack Heredia, Kevin Ness, Bill Colston