Abstract: Disclosed are grips and methods of making grips for use with the handle of an article, and in particular for use with fishing poles and golf clubs. Grips preferably include a multi-layered gripping member and an inner sleeve or mounting body. The gripping member can include an outer layer with a fabric layer coated and preferably saturated by polyurethane. The outer layer can be bonded to an inner layer to form the gripping member which is then attached to the sleeve. The sleeve can be ground from a starting block of material or may be injection molded. Also disclosed are handles including a connector configured to couple to a portion of a fishing pole. Such handles may include a multiple layers and can be selectively removed from the article. Methods are also provided for selectively coupling exchangeable handles to articles including fishing poles.

Abstract: Disclosed are grips and methods of making grips for use with the handle of an article, and in particular for use with fishing poles and golf clubs. Grips preferably include a multi-layered gripping member and an inner sleeve or mounting body. The gripping member can include an outer layer with a fabric layer coated and preferably saturated by polyurethane. The outer layer can be bonded to an inner layer to form the gripping member which is then attached to the sleeve. The sleeve can be ground from a starting block of material or may be injection molded. Also disclosed are handles including a connector configured to couple to a portion of a fishing pole. Such handles may include a multiple layers and can be selectively removed from the article. Methods are also provided for selectively coupling exchangeable handles to articles including fishing poles.

Abstract: This application relates to the field of smart terminal technologies, and specifically, to a display control method, an electronic device, and a readable storage medium. The method includes: The electronic device displays a first interface, where the first interface includes a first window of a first application; in response to a first operation of a user on the first interface, displays a first trajectory corresponding to the first operation, where the first trajectory surrounds at least a part of a first target; in response to ending the first operation by the user, converts the first trajectory into a second trajectory, displays the second trajectory, and displays a first control on the second trajectory, where the second trajectory is determined based on an edge of the first target, and the first target is located in the second trajectory.

Abstract: The present disclosure provides a method and apparatus for building a database for retrieval. An implementation of the method comprises: acquiring a data set, and dividing the data set into a first data set and a second data set; clustering the data in the first data set, to obtain at least one first-level cluster center; clustering the data in the first data set based on the first-level cluster center, to obtain corresponding at least one second-level cluster center; obtaining a codebook corresponding to the first data set based on residuals between the data in the first data set and the first-level cluster center and residuals between the data in the first data set and the second-level cluster center; and training the second data set based on the codebook corresponding to the first data set, to obtain a codebook corresponding to the data set.

Abstract: In a method for efficiently inducing reprogramming of human cells into neuronal cells, a concentration of cAMP is increased or an expression of PKA and CREB is up-regulated or an expression of AMPK, ALK2, ALK3, P38, and JNK is inhibited by a single small molecule compound or gene knockout or gene overexpression. In the present disclosure, the induction small molecule compound is single and safe, and has a short induction time, high induction efficiency, definite induction sites and genes, and clear molecular regulation mechanism. The small molecule compound can be applied to the clinical treatment of human neurodegenerative diseases, providing a safer and more efficient treatment method for the neurodegenerative diseases. Since neuronal cells cannot divide and proliferate, the method induces fibroblasts and astrocytes that can divide and proliferate in vitro and in vivo, to continuously obtain a large number of induced neuronal cells in vitro and in vivo.

Abstract: Disclosed are grips and methods of making grips for use with the handle of an article, and in particular for use with fishing poles and golf clubs. Grips preferably include a multi-layered gripping member and an inner sleeve or mounting body. The gripping member can include an outer layer with a fabric layer coated and preferably saturated by polyurethane. The outer layer can be bonded to an inner layer to form the gripping member which is then attached to the sleeve. The sleeve can be ground from a starting block of material or may be injection molded. Also disclosed are handles including a connector configured to couple to a portion of a fishing pole. Such handles may include a multiple layers and can be selectively removed from the article. Methods are also provided for selectively coupling exchangeable handles to articles including fishing poles.

Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.

Abstract: The present disclosure provides a method for inducing transdifferentiation of somatic cells into mammary epithelial cells in vitro using a small molecule compound. The method includes: inhibiting an expression of TGFbeta R1 and related sites thereof, to induce the transdifferentiation of the somatic cells into the mammary epithelial cells in vitro. The present disclosure fills a gap in the technology of inducing the transdifferentiation of fibroblasts to the mammary epithelial cells using the small molecule compound; the present disclosure also provides a research platform for in vitro researches on a mammary gland bioreactor, mammary gland development and differentiation, breast cancer, and transdifferentiation of the fibroblasts into other types of functional cells.

Abstract: The present disclosure provides a method and apparatus for building a database for retrieval. An implementation of the method comprises: acquiring a data set, and dividing the data set into a first data set and a second data set; clustering the data in the first data set, to obtain at least one first-level cluster center; clustering the data in the first data set based on the first-level cluster center, to obtain corresponding at least one second-level cluster center; obtaining a codebook corresponding to the first data set based on residuals between the data in the first data set and the first-level cluster center and residuals between the data in the first data set and the second-level cluster center; and training the second data set based on the codebook corresponding to the first data set, to obtain a codebook corresponding to the data set.

Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.

Abstract: Disclosed are grips and methods of making grips for use with the handle of an article, and in particular for use with fishing poles and golf clubs. Grips preferably include a multi-layered gripping member and an inner sleeve or mounting body. The gripping member can include an outer layer with a fabric layer coated and preferably saturated by polyurethane. The outer layer can be bonded to an inner layer to form the gripping member which is then attached to the sleeve. The sleeve can be ground from a starting block of material or may be injection molded. Also disclosed are handles including a connector configured to couple to a portion of a fishing pole. Such handles may include a multiple layers and can be selectively removed from the article. Methods are also provided for selectively coupling exchangeable handles to articles including fishing poles.

Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.

Abstract: Disclosed are grips and methods of making grips for use with the handle of an article, and in particular for use with fishing poles and golf clubs. Grips preferably include a multi-layered gripping member and an inner sleeve or mounting body. The gripping member can include an outer layer with a fabric layer coated and preferably saturated by polyurethane. The outer layer can be bonded to an inner layer to form the gripping member which is then attached to the sleeve. The sleeve can be ground from a starting block of material or may be injection molded. Also disclosed are handles including a connector configured to couple to a portion of a fishing pole. Such handles may include a multiple layers and can be selectively removed from the article. Methods are also provided for selectively coupling exchangeable handles to articles including fishing poles.

Abstract: A grip member and a method of making such a grip member including at least a polymerized region with two or more polymers. The first and second polymers cooperate to each form a portion of the top surface of the region. The region may be combined with a substrate to form a sheet. The sheet may be formed into a grip interface having any of a number of shapes including a panel shape. In the case of a panel shaped grip interface, the panel can then be attached to an underlisting sleeve to form the grip. Some versions of such a grip reduce impact shock and provide a feeling of tackiness in the manner of a spirally wrapped polyurethane-felt grip while allowing the use of multiple colors being polymerized together. The grip may be easily installed onto a golf club shaft and may further accommodate the use of polymers including various different characteristics including level of tackiness or durometer.

Abstract: Reel components, such as reel knobs, and methods of assembling the reel components are disclosed herein. The reel knob can include a base and a gripping member. The base can include a recessed area. The gripping member can comprise a resilient material. The gripping member can be sized and shaped to correspond to the recessed area. The gripping member can be adhered to the recessed area. The base can be pressed down onto the gripping member to join the base to the gripping member.

Abstract: In certain embodiments, a system is provided for the efficient removal of an old grip from a fishing pole while maintaining the integrity of the pole. The system can include a removal portion including one or more rotational assemblies that rotate one or more grinding members. The grinding members can include a rotational blade with a centering rod. The rotational assembly can remove the old grip while maintaining the integrity of the rod within. The system can include multiple sets of grinding members that are organized for efficient identification or may include adjustable grinding members that can be configured for specific rods. The system can further include a guide to help identify particular grinding members for use with particular fishing poles.