Patents by Inventor Ben Lange De

Ben Lange De has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the preparation of enantiomerically enriched compounds
    Patent number: 6794542
    Abstract: Process for the preparation of a diasteromerically enriched phenylglycine amide derivative in which an enantiomerically enriched phenylglycine amide is converted into the corresponding Schiff base with the aid of compound R2—C(O)—R3, and the Schiff base obtained is subsequently converted into the diastereomerically enriched phenyglycine amide derivative with the aid of a cyanide source, a reducing agent or an allyl organometallic compound. The phenylglycine amide derivatives obtained are interesting starting materials for the preparation of for example enantiomerically enriched &agr;- and or &bgr;-amino acids and derivatives thereof, such as amides and esters, and amines.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: September 21, 2004
    Assignee: DSM N.V.
    Inventors: Wilhelmus Hubertus Joseph Boesten, Harold Monro Moody, Bernardus Kaptein, Johannes Paulus Gerardus Seerden, Marcelles Van Der Sluis, Ben Lange De, Quirinus Bernardus Broxterman
  • Preparation of enantiomerically enriched amine-functionalized compounds
    Publication number: 20040006225
    Abstract: Process for removing a residual fragment of a chiral auxiliary from a diastereomeric compound with formula (2) 1
    Type: Application
    Filed: November 26, 2002
    Publication date: January 8, 2004
    Inventors: Marcelles Sluis Van Der, Quirinus Bernardus Broxterman, Ben Lange De
  • Method for the preparation of enantiomerically enriched compounds
    Publication number: 20030097005
    Abstract: Process for the preparation of a diasteromerically enriched phenylglycine amide derivative in which an enantomerically enriched phenylglycine amide is converted into the corresponding Schiff base with the aid of compound R2—C(O)—R3, and the Schiff base obtained is subsequently converted into the diastereomerically enriched phenyglycine amide derivative with the aid of a cyanide source, a reducing agent or an allyl organometallic compound. The phenylglycine amide derivatives obtained are interesting starting materials for the preparation of for example enantimerically enriched &agr;- and or &bgr;-amino acids and derivatives thereof, such as amides and esters, and amines.
    Type: Application
    Filed: October 9, 2002
    Publication date: May 22, 2003
    Inventors: Wilhelmus Hubertus Joseph Boesten, Harold Monro Moody, Bernardus Kaptein, Johannes Paulus Gerardus Seerden, Marcelles Van Der Sluis, Ben Lange De, Quirinus Bernardus Broxterman