Abstract: The present invention relates to compounds of formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, intermediate compounds useful in such preparations, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.

Abstract: The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.

Abstract: The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.

Abstract: The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.

Abstract: An embossing tool for use with a rotating embossing roller, including: a tool body having a tool surface; and an array of recesses set into the tool surface to form a desired embossing surface profile, wherein at least two of the recesses are interconnected by a passage to enable fluid communication therebetween during embossing.

Abstract: A method of measuring a defect level of a region of a substrate for a security document, wherein the defect level is associated with reduced transparency of the region of the substrate, the method including the steps of: digitally imaging the region to create a digital image, the digital image containing light intensity data; and analysing the digital image including: calculating a statistical measure of the light intensity data in the region; and assigning a defect score to the region based on the statistical measure of the light intensity data in the region.

Abstract: A security document includes a substrate including a first surface and a second surface; a foil located in a region of the substrate on the first surface and including a first security element: and a second security element located in a different region of the substrate. The first and second security elements are configured to provide a visual effect when overlapping. The second security element is formed from an embossable material applied directly to the surface of the substrate. A method is for the production thereof.

Abstract: Improved method for separating gases from a gas mixture, whereby the gas mixture to be treated is led through a membrane separator (3) by means of a compressor installation (2) and whereby the compressed gas mixture to be treated is cooled in the compressor installation (2), among others in order to separate condensate from the gas mixture, after which, as it leaves the compressor installation (2), it will be re-heated before it ends up in the membrane separator (3), characterized in that, in order to re-heat the gas mixture to be treated as it leaves the compressor installation (2), use is made of the recuperation heat of the compressor installation (2) itself.

Abstract: Gas drying device, consisting of a desiccant dryer (2) which makes use of a pressure tank (4) with a drying zone (5) and a regeneration zone (6), with an adsorption and/or absorption medium (7) which is alternately guided through the drying zone (5) and the regeneration zone (6); a primary circuit (8) in which the abovementioned desiccant dryer (2) is included, which makes it possible to guide the gas to be dried through the drying zone (5) of the desiccant dryer (2); a secondary circuit (9) which makes it possible for a part of the gas to be dried to be guided through the regeneration zone (6) of the desiccant dryer (2) and to absorb moisture there, characterized in that the device also contains a cooling dryer (1) which is inserted upstream the abovementioned desiccant dryer (2) in the primary circuit (8).

Abstract: Method for drying a gas from a compressor (1) by means of a drier (2) of the type which consists of a pressure tank (3) with a drying zone (4) and a regeneration zone (5), with a rotor (6) which is composed of a drying element (7) in which has been provided an adsorption and/or absorption medium (8) which is alternately put through the drying zone (4) and the regeneration zone (5), characterised in that at a low load or zero load, the inlet of the regeneration zone (5) is connected to the user network (12) via a regeneration pipe (27), and in that the outlet of the regeneration zone (5) is connected to the atmosphere.

Abstract: The present invention relates to a method of forming nanostructures or nanomaterials. The method comprises providing a thermal control barrier on a substrate and forming the nanostructures or nanomaterials. The method may, for example, be used to form carbon nanotubes by plasma enhanced chemical vapour deposition using a carbon containing gas plasma: The temperature of the substrate may be maintained at less than 350° C. while the carbon nanotubes are formed.

Abstract: Method for drying a gas from a compressor (1) by means of a drier (2) of the type which consists of a pressure tank (3) with a drying zone (4) and a regeneration zone (5), with a rotor (6) which is composed of a drying element (7) in which has been provided an adsorption and/or absorption medium (8) which is alternately put through the drying zone (4) and the regeneration zone (5), characterised in that at a low load or zero load, the inlet of the regeneration zone (5) is connected to the user network (12) via a regeneration pipe (27), and in that the outlet of the regeneration zone (5) is connected to the atmosphere.

Abstract: Gas drying device, consisting of a desiccant dryer (2) which makes use of a pressure tank (4) with a drying zone (5) and a regeneration zone (6), with an adsorption and/or absorption medium (7) which is alternately guided through the drying zone (5) and the regeneration zone (6); a primary circuit (8) in which the above-mentioned desiccant dryer (2) is included, which makes it possible to guide the gas to be dried through the drying zone (5) of the desiccant dryer (2); a secondary circuit (9) which makes it possible for a part of the gas to be dried to be guided through the regeneration zone (6) of the desiccant dryer (2) and to absorb moisture there, characterised in that the device also contains a cooling dryer (1) which is inserted upstream the abovementioned desiccant dryer (2) in the primary circuit (8).

Abstract: A pitch control system for a bulldozer having a bulldozer blade that is mounted to a blade linkage. The bulldozer blade is coupled to the blade linkage by a bearing that permits the right and left angling movement of the bulldozer blade and the forward and rearward pitch of the bulldozer blade relative to the blade linkage. An angling control valve hydraulically positions two hydraulic angling cylinders for angling the blade right and left relative to the blade linkage. A hydraulic dump valve is hydraulically positioned between the angling hydraulic control valve and the hydraulic angling cylinder, the hydraulic dump valve having a dump position and a checked position. A linear actuator in the form of a hydraulic pitch cylinder is operatively positioned between the blade linkage and the blade for selectively adjusting the pitch of the blade relative to the blade linkage. A pitch control valve is used to selectively position the pitch cylinder.