Patents by Inventor Benda Arlene SCHULMAN

Benda Arlene SCHULMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICALLY ACTIVE PYRAZOLO-PYRIDONE MODULATORS OF DCN1/2-MEDIATED CULLIN NEDDYLATION
    Publication number: 20220280488
    Abstract: A DCN1/2-mediated cullin neddylation modulator; a method for treating disorders associated with dysfunctional DCN1 and/or UBC12, Alzheimer's disease, other neurodegenerative diseases, bacterial infections, or viral infections; and a method for treating cancers are provided. The DCN1/2-mediated cullin neddylation modulator includes a compound according to Formula I disclosed herein. The methods include administering to a mammal a therapeutically effective amount of a compound according to Formula I. Also provided herein is a pharmaceutical composition including a therapeutically effective amount of a compound according to Formula I, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 22, 2020
    Publication date: September 8, 2022
    Applicants: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, MEMORIAL SLOAN-KETTERING CANCER CENTER, St. Jude Children's Research Hospital, Inc.
    Inventors: Hoshin KIM, Rodney Kiplin GUY, Jared T. HAMMILL, Daniel Charles SCOTT, Benda Arlene SCHULMAN, Bhuvanesh SINGH