Abstract: Techniques for culling primitives are provided herein. The techniques involve automatic generation of shader programs to be executed by an accelerated processing device. A just-in-time compiler automatically generates the shader programs based on a vertex shader program that is provided for use in the vertex shader stage of the graphics processing pipeline. The automatically generated shader programs include instructions from the vertex shader program that transform the positions of vertices provided as input to the graphics processing pipeline to generate transformed input vertices. The shader programs also include instructions to cull primitives based on the transformed input vertices. After generating the automatically generated shader programs, the software module transmits the automatically generated shader programs to the graphics processing pipeline for execution.

Abstract: Techniques for culling primitives are provided herein. The techniques involve automatic generation of shader programs to be executed by an accelerated processing device. A just-in-time compiler automatically generates the shader programs based on a vertex shader program that is provided for use in the vertex shader stage of the graphics processing pipeline. The automatically generated shader programs include instructions from the vertex shader program that transform the positions of vertices provided as input to the graphics processing pipeline to generate transformed input vertices. The shader programs also include instructions to cull primitives based on the transformed input vertices. After generating the automatically generated shader programs, the software module transmits the automatically generated shader programs to the graphics processing pipeline for execution.

Abstract: A C-terminally modified Ubiquitin (Ub) derivative) ubiquitin vinyl sulfone (UbVS), which is specific for deubiquitinating enzymes (DUBs), was synthesized as an active site directed probe that irreversibly modifies a subset of Ub C-terminal hydrolases (UCHs) and Ub specific processing proteases (UBPs), is provided. [125I]-UbVS modifies 6 of the 17 known and putative yeast deubiquitinating enzymes, namely Yuh1p, Ubp1p, Ubp2p, Ubp6p, Ubp12p and Ubp15p. In mammalian cells, a greater number of polypeptides is labeled, most of which are DUBs. An additional DUB that associates with the mammalian 26S proteasome, novel protein USP14, a mammalian homolog of yeast Ubp6p that is bound to the proteasome, is provided.