Abstract: An implant with anti-inflammatory or antibacterial effects, or both, for implantation in a human or animal body, the implant having a set of porous grains or granules, wherein at least a plurality of the porous grains or granules include titanium, one or more titanium oxides or titanium alloy and have a titanium oxide layer on their surface and have a mean length from one side to the opposite side, through a geometrical center, of at least 200 ?m and up to 5 mm and a mean specific surface area of at least 0.15 m2/g according to the BET method. Also featured is a population of grains or granules having anti-inflammatory or antibacterial effects, or both. Further featured is a method of producing an implant, a method for deriving a population of grains or granules, and a method for treating a condition with a porous grain or granule.

Abstract: The present invention provides a porous block for implantation in the maxillofacial area of a human or animal, wherein the porous block:—comprises titanium metal and/or a titanium alloy;—has a porosity of at least 40%;—is a geometrical structure shaped to fit at least a part of a degraded alveolar process of the human or animal; and—as an intended bone contacting surface intended to be in contact with the bone surface of an implantation site in the maxillofacial area of the human or animal, wherein said bone contacting surface has pores extending through the porous block and wherein at least some of these pores have a pore diameter size of at least 50 ?m to ensure bone ingrowth; and wherein—the porous block is a geometrical structure having a width, a height and a length, said intended bone contacting surface being defined by the width and the length, wherein the average value of the width is in the range of 5-10 mm, the average value of the height is in the range of 3-10 mm and the average value of the lengt

Abstract: A method is provided for treatment of a condition including at least one weakened vertebra or one compression fracture of a vertebra, wherein in at least one embodiment, the vertebra is injected by vertebroplasty or kyphoplasty with particles, grains or granules or a mixture thereof, or an implant suspension including at least one resorbable fluid vehicle and particles, grains or granules or a mixture thereof, wherein the particles, grains or granules individually have a mean length from one side to the opposite side, through a geometrical centre, of up to 5 mm. Moreover, at least one embodiment of the present invention also provides use of the particular or granular material disclosed above, for the manufacture of a medicament for the vertebroplastic treatment or kyphoplastic treatment of a condition including at least one weakened vertebra or one compression fracture of a vertebra.

Abstract: The present invention refers to a method for treatment of an inflammatory and/or bacterial condition, wherein particles of microstructure comprising titanium, titanium alloy, at least one titanium oxide or a combination thereof, and having a surface with at least a substantial part consisting of at least one type of titanium oxide, are brought into contact with at least one infected site in a human or animal body by insertion, injection or implantation, which at least one infected site exhibits the inflammatory and/or bacterial condition. Moreover, the present invention refers to an injectable suspension comprising the particles according to the invention and a fluid vehicle for use as a medicament. Finally, the present invention also defines use of the particles of microstructure according to the invention for the manufacture of a medicament in the form of an injectable suspension.

Abstract: The present invention is related to an implant with anti-inflammatory or antibacterial effects, or both, the implant being intended for implantation in a human or an animal body, the implant comprising at least one porous grain or granule, wherein the at least one porous grain or granule comprises titanium, one or more titanium oxides or titanium alloy and has a titanium oxide layer on its surface; has a mean length from one side to the opposite side, through a geometrical centre, of up to 5 mm; has a mean specific surface area of at least 0.15 m2/g according to the BET method. Moreover, disclosed is also a method for treating a condition comprising an inflammation or/and an infection present in a human or animal body with implants according to the invention.

Abstract: In a method and a device for improving the fixing of an elongate prosthesis in a bone cavity, said fixing being provided by a bed in which the prosthesis has been driven down by vibration, a ring of a flexible, essentially plastic material is arranged around the proximal part of the prosthesis so that the ring fills the space between the bone wall and the prosthesis, whereupon the ring is compacted and compressed, after which strokes are made on the prosthesis in its longitudinal direction for final fixing thereof in the bed. The ring significantly improves the strength of the prosthesis in the bed.

Abstract: A method and an insertion unit for inserting an elongate prosthesis into a prosthesis fixing device. This device comprises a bed of grains and biocompatible material, and a vibrating tool is used for insertion, the vibration head of which performs an oscillating motion back and forth about a swivelling axis (3?). According to the invention, said axis (3r) of the vibrating tool essentially coincides with the longitudinal axis (I1) of the elongate prosthesis (1). The method and the insertion unit provide a prosthesis fixing device consisting of said bed, in which the grains are evenly packed along the length of the prosthesis.