Abstract: The present invention relates to an apparatus for conducting assays on samples and/or processing of samples. The apparatus comprises a rotatably arranged cylindrical sample holder for holding a sample at a lateral surface of the cylindrical sample holder. The cylindrical sample holder is configured to be at least partly covered by a liquid layer. The apparatus further comprises a liquid dispensing means configured to add liquid to the liquid layer, a reagent dispensing means configured to add a reagent to the liquid layer and a liquid contacting means configured to distribute liquid within said liquid layer. The liquid contacting means comprises a plate-like element flexibly assembled in relation to the cylindrical sample holder. The present invention also relates to a method for conducting assays on samples and/or processing of samples.

Abstract: A sample holder (100) for an apparatus (300) configured to perform an assay at a plurality of sample sites (130) is disclosed, wherein each sample site comprises a concatemer. The sample holder comprises a rotatable body (110), a matrix layer (120) and a liquid layer arranged on the matrix layer. The plurality of samples sites are distributed in the matrix layer in both a lateral direction and a thickness direction of the matrix layer, and the rotatable body is configured to be arranged in the apparatus to be rotatable around an axis (A) while the assay is performed at the plurality of sample sites. A corresponding method (200) and apparatus (300) are also disclosed.

Abstract: The present invention relates to an apparatus for conducting assays on samples and/or processing of samples. The apparatus comprises a rotatably arranged cylindrical sample holder for holding a sample at a lateral surface of the cylindrical sample holder. The cylindrical sample holder is configured to be at least partly covered by a liquid layer. The apparatus further comprises a liquid dispensing means configured to add liquid to the liquid layer, a reagent dispensing means configured to add a reagent to the liquid layer and a liquid contacting means configured to distribute liquid within said liquid layer. The liquid contacting means comprises a plate-like element flexibly assembled in relation to the cylindrical sample holder. The present invention also relates to a method for conducting assays on samples and/or processing of samples.

Abstract: A method and apparatus are provided, in which an observation volume is defined by a volume where light from illumination means and a field of view of detection means overlap. The central axes of said light from the illumination means and said field of view of the detection means are non-parallel, and the sample is transported through the observation volume during imaging, preferably by rotation of a sample container holding the sample.

Abstract: An apparatus for imaging a includes an light source for illuminating the sample simultaneously in a line focus or an array of foci; and a sensor for detecting photons emitted or scattered from the sample simultaneously in an array of fields of view. An array of sub-observation volumes in the sample, from which photons are emitted or scattered during imaging, is defined by the volumes in space where the line focus or array of foci from the light source overlap with the corresponding array of field of views of the sensor. A cylindrical sample holder holds the sample at a surface and is rotatably arranged such that at least a portion of the sample can be transported through at least one of the sub-observation volumes by rotating the sample holder. The apparatus can be used in a high-throughput method of imaging.

Abstract: An apparatus for imaging a includes an light source for illuminating the sample simultaneously in a line focus or an array of foci; and a sensor for detecting photons emitted or scattered from the sample simultaneously in an array of fields of view. An array of sub-observation volumes in the sample, from which photons are emitted or scattered during imaging, is defined by the volumes in space where the line focus or array of foci from the light source overlap with the corresponding array of field of views of the sensor. A cylindrical sample holder holds the sample at a surface and is rotatably arranged such that at least a portion of the sample can be transported through at least one of the sub-observation volumes by rotating the sample holder. The apparatus can be used in a high-throughput method of imaging.

Abstract: A method and apparatus are provided, in which an observation volume is defined by a volume where light from illumination means and a field of view of detection means overlap. The central axes of said light from the illumination means and said field of view of the detection means are non-parallel, and the sample is transported through the observation volume during imaging, preferably by rotation of a sample container holding the sample.

Abstract: There is disclosed an optical device for dispersion compensation of channels within a predetermined wavelength band, comprising: a waveguiding structure; and a grating structure formed in said waveguiding structure; characterized in that said grating structure has a Bragg frequency profile that is divided into contiguous periods, wherein the Bragg frequencies within each period vary between a lower Bragg frequency and an upper Bragg frequency, said lower and upper Bragg frequencies for each period both corresponding to wavelengths outside of said predetermined wavelength band.

Abstract: Improvements relating to thermally tunable fiber optical devices have been disclosed. In one aspect, a thermally tunable fiber Bragg grating device is provided with one or more heaters to (3a, 3b) produce a desired temperature profile along the grating, and one or more supporting auxiliary heaters (5a, 5b) are provided at the edges of the grating in order to compensate for temperature drops caused by heat loss to lower temperature surroundings. In another aspect, two heating structures are thermally connected to each other, such that dissipated heat from one of the structures supports the heating effect of the other structure.

Abstract: The present invention relates to an optical component, which comprises an optical fibre, which has a minimal functional arc radius in each point thereof, and which includes a thermally compensated portion, and a Bragg grating provided in a region of the thermally compensated portion. The optical fibre component comprises furthermore a temperature-compensating structure, which holds the thermally compensated portion of the optical fibre under tension in a linear direction for athermalizing the Bragg grating, and a housing for mechanical protection of the Bragg grating, which is provided with at least a first lead-through, and which housing has a maximal extension in the linear direction from a first housing end to a second housing end. The first lead-through has an exit end located outside the housing and an entrance end located inside the housing.

Abstract: A spectrally selective optical switch is disclosed. The switch comprises a first and a second optical waveguide each having a light guiding structure arranged to guide light along a predetermined path, the optical waveguides being arranged adjacent and parallel to each other; an external resonator defined by a first and a second mirror, said first and said second mirror being provided on opposite sides and outside of said first and second light guiding structures, and said external resonator being resonant to a specific wavelength; and a deflector provided in each of said first and second optical waveguide, the deflectors being arranged to deflect light propagating in one of the light guiding structures to the other light guiding structure by operation of said external resonator. A matrix switch is also disclosed.

Abstract: There is disclosed an optical device for dispersion compensation of channels within a predetermined wavelength band, comprising: a waveguiding structure; and a grating structure formed in said waveguiding structure; characterized in that said grating structure has a Bragg frequency profile that is divided into contiguous periods, wherein the Bragg frequencies within each period vary between a lower Bragg frequency and an upper Bragg frequency, said lower and upper Bragg frequencies for each period both corresponding to wavelengths outside of said predetermined wavelength band.

Abstract: A spectrally selective optical coupler is disclosed, comprising a first and a second waveguide; an external resonator defined by at least a first and a second mirror; and a respective deflecting portion in each of said waveguides for coupling light between the waveguide and the external resonator. The waveguides are arranged between the mirrors adjacent to each other in a plane that is generally parallel to said mirrors; and the external resonator is designed such that a resonant mode within the external resonator overlaps the deflecting portion in the first and the second waveguide. The inventive coupler solves some limiting geometrical problems encountered in the prior art. A lateral extension of a mode in the external resonator overlapping both waveguides is obtained using a curved resonator mirror or refractive elements or portions within the resonator.

Abstract: The invention is a spectrally selective optical coupler with a new geometry and a new principle of action. An optical coupler according to the invention comprises an optical fiber and an external lightguide. In the fiber there is provided a deflector that is operative to deflect light of a predetermined wavelength into a propagating mode of said lightguide. The outcoupled light is transferred to a region remote from the outcoupling portion of the fiber. The invention can be used to couple light from a first to a second optical fiber.

Abstract: A spectrally selective optical coupler is disclosed, comprising a first and a second waveguide; an external resonator defined by at least a first and a second mirror; and a respective deflecting portion in each of said waveguides for coupling light between the waveguide and the external resonator. The waveguides are arranged between the mirrors adjacent to each other in a plane that is generally parallel to said mirrors; and the external resonator is designed such that a resonant mode within the external resonator overlaps the deflecting portion in the first and the second waveguide. The inventive coupler solves some limiting geometrical problems encountered in the prior art. A lateral extension of a mode in the external resonator overlapping both waveguides is obtained using a curved resonator mirror or refractive elements or portions within the resonator.

Abstract: An apparatus for determining the topography, shape, or form of (machined) objects is disclosed. The apparatus operative to perform consecutive measurements of the optical path difference (OPD) between a reference surface on one hand and a series of laterally displaced points on one or more partially reflecting surfaces of an object on the other hand. The inventive apparatus comprises light source means for emitting light that is swept in optical frequency; means for exposing said surfaces to light from said light source means; means for combining and detecting the light reflected back by said surfaces; means for performing a frequency analysis of the detected signal; and means for calculating OPD from the obtained frequencies. The speed of the frequency sweep is preferably above 50 GHz/?s.

Abstract: The invention relates to methods and arrangements for channel balancing of a wavelength division multiplexed optical signal. Channel balancing according to the invention is performed by using a resonator that provides a selection region in which a selected channel has a substantially increased poser density relative to channels out of resonance. The selected channel is attenuated a desired amount, i.e. a desired amount of power is removed therefrom, by adjusting the properties of the selection region. In a preferred embodiment, attenuation is achieved by adjusting the selection region such that destructive interference is obtained for the selected channel in a fiber carrying tile multiplexed optical signal.

Abstract: A novel method and apparatus for fabrication of blazed and slanted fiber Bragg gratings is disclosed. The method comprises the step of simultaneously exposing the fiber with two mutually coherent light beams so as to create an interference pattern along a longitudinal axis of the fiber, wherein each one of said beams is brought into a line focus, which coincides with the core of the fiber. Further, the plane comprising the beams is rotated to provide a second angle relative to the fiber direction, said rotation giving rise to a blazing angle of the photo-induced grating elements.

Abstract: A spectrally selective optical switch is disclosed. The switch comprises a first and a second optical waveguide each having a light guiding structure arranged to guide light along a predetermined path, the optical waveguides parallel to each other; an external resonator defined by a first and a second mirror, said first and said second mirror being provided on opposite sides and outside of said first and second light guiding structures, and said external resonator being resonant to a specific wavelength; and a deflector provided in each of said first and second optical waveguide, the deflectors being arranged to deflect light propagating in one of the light guiding structures to the other light guiding structure by operation of said external resonator. A matrix switch is also disclosed.

Abstract: The invention relates to the coupling of light to and from an optical waveguide, such as an optical fiber. Light of a specific wavelength is deflected out from the fiber, or into the fiber, in a substantially transverse direction with respect to the propagation direction of light in the waveguide, by a deflector 16 arranged in the fiber core 10. Wavelength selectivity of the deflector 16 is provided by a Bragg grating means located in the fiber core 10. The deflected light is collimated, or converged towards a focus, by an interface 15 between a cladding 11, having one index of refraction, and an outer medium 12, having another index of refraction. The ratio between the radius of the cladding 11 and the radius of the core 10 made sufficiently small for the collimating, or converging, effect to appear.