Patents by Inventor Benjamin A. Alman

Benjamin A. Alman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating fibroproliferative disorders in a mammal
    Patent number: 10722493
    Abstract: Methods of treating fibroproliferative disorders mediated by ?-catenin in mammals, including aggressive fibromatoses, also called desmoid tumour.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: July 28, 2020
    Assignee: The Hospital for Special Children
    Inventors: Benjamin A. Alman, Raymond Poon, Helen Hong, Gene Gauzer
  • METHODS FOR TREATING FIBROPROLIFERATIVE DISORDERS IN A MAMMAL
    Publication number: 20170281594
    Abstract: A topical drug composition for treating a ?-catenin-mediated disorder in a mammal is provided comprising a Nefopam compound selected from Nefopam, or a functionally equivalent analogue, prodrug, salt or solvate thereof.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 5, 2017
    Inventors: Benjamin A. Alman, Raymond Poon, Helen Hong, Gene Gauzer
  • METHODS AND FORMULATIONS FOR TREATING SCARS AND BETA-CATENIN-MEDIATED DISORDERS
    Publication number: 20170172980
    Abstract: A topical drug composition for treating a ?-catenin-mediated disorder in a mammal is provided comprising a Nefopam compound selected from Nefopam, or a functionally equivalent analogue, prodrug, salt or solvate thereof.
    Type: Application
    Filed: December 24, 2016
    Publication date: June 22, 2017
    Inventors: Benjamin A. Alman, Raymond Poon, Helen Hong, Gene Gauzer
  • Methods and formulations for treating scars and ?-catenin-mediated disorders
    Patent number: 9566263
    Abstract: A topical drug composition for treating a ?-catenin-mediated disorder in a mammal is provided comprising a Nefopam compound selected from Nefopam, or a functionally equivalent analog, prodrug, salt or solvate thereof.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: February 14, 2017
    Assignee: Hospital for Sick Children
    Inventors: Benjamin A. Alman, Raymond Poon, Helen Hong, Gene A. Gauzer
  • Method of treating scars and ?-catenin-mediated disorders using Nefopam compounds
    Patent number: 8957107
    Abstract: Methods of treating disorders mediated by ?-catenin comprising administration of Nefopam compounds are provided In particular, the treatment of disorders arising from excessive or undesired expression of ?-catenin is contemplated Said compounds include Nefopam, analogues thereof, prodaigs thereof, and salts and solvates of Nefopam The ?-catenin mediated disorders are preferably selected from the group consisting of fibroproliferative disorders (such as scars, aggressive fibramtoses, and fibroses) and cancer (such as colon cancer, melanoma, liver cancer, ovarian cancer, endometrial cancer, medullobalstoma pilomatricomas, and prostate cancer)
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: February 17, 2015
    Assignee: The Hospital for Sick Children
    Inventors: Benjamin A. Alman, Raymond Poon, Helen Hong
  • METHOD OF TREATING SCARS AND B-CATENIN-MEDIATED DISORDERS USING NEFOPAM COMPOUNDS
    Publication number: 20120294928
    Abstract: Methods of treating disorders mediated by ?-catenin comprising administration of Nefopam compounds are provided In particular, the treatment of disorders arising from excessive or undesired expression of ?-catenin is contemplated Said compounds include Nefopam, analogues thereof, prodaigs thereof, and salts and solvates of Nefopam The ?-catenin mediated disorders are preferably selected from the group consisting of fibroproliferative disorders (such as scars, aggressive fibramtoses, and fibroses) and cancer (such as colon cancer, melanoma, liver cancer, ovarian cancer, endometrial cancer, medullobalstoma pilomatricomas, and prostate cancer)
    Type: Application
    Filed: December 15, 2010
    Publication date: November 22, 2012
    Inventors: Benjamin A. Alman, Raymond Poon, Helen Hong