Patents by Inventor Benjamin A. Apker

Benjamin A. Apker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240216906
    Abstract: Humidified sample preparation station for serial crystallography according to one embodiment is a humidified enclosure that delivers relative humidities above 95% and preferably above 97% in standard operation, and that can allow microscope observation of samples within. Humidified sample preparation station for serial crystallography can be used for preparation of protein crystal samples for examination using X-rays and for protein structure determination by X-ray crystallography, involving addition of liquid to the sample and removal of liquid from the sample using vacuum or suction.
    Type: Application
    Filed: January 25, 2024
    Publication date: July 4, 2024
    Applicant: Mitegen, LLC
    Inventors: Richard Jayne, David Closs, Benjamin A. Apker, Robert E. Thorne
  • Patent number: 11925931
    Abstract: Humidified sample preparation station for serial crystallography according to one embodiment is a humidified enclosure that delivers relative humidities above 95% and preferably above 97% in standard operation, and that can allow microscope observation of samples within. Humidified sample preparation station for serial crystallography can be used for preparation of protein crystal samples for examination using X-rays and for protein structure determination by X-ray crystallography, involving addition of liquid to the sample and removal of liquid from the sample using vacuum or suction.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: March 12, 2024
    Assignee: MiTeGen, LLC
    Inventors: Richard Jayne, David Closs, Benjamin A. Apker, Robert E. Thorne
  • Publication number: 20220412635
    Abstract: A cryogenic cooling manifold and methods incorporating a cryogenic cooling manifold for managing the gas layer(s) above a liquid cryogen to control cooling temperature-time profiles and ice formation for microliter and smaller samples that are plunged through the gas and into the liquid cryogen.
    Type: Application
    Filed: September 1, 2022
    Publication date: December 29, 2022
    Applicant: MiTeGen, LLC
    Inventors: David Closs, Stephen Hollabaugh, Robert E. Thorne, Robert Newman, Benjamin A. Apker
  • Patent number: 11473826
    Abstract: A cryogenic cooling manifold and methods incorporating a cryogenic cooling manifold for managing the gas layer(s) above a liquid cryogen to control cooling temperature-time profiles and ice formation for microliter and smaller samples that are plunged through the gas and into the liquid cryogen.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: October 18, 2022
    Assignee: MiTeGen, LLC
    Inventors: David Closs, Stephen Hollabaugh, Robert E. Thorne, Robert Newman, Benjamin A. Apker
  • Publication number: 20220040685
    Abstract: Humidified sample preparation station for serial crystallography according to one embodiment is a humidified enclosure that delivers relative humidities above 95% and preferably above 97% in standard operation, and that can allow microscope observation of samples within. Humidified sample preparation station for serial crystallography can be used for preparation of protein crystal samples for examination using X-rays and for protein structure determination by X-ray crystallography, involving addition of liquid to the sample and removal of liquid from the sample using vacuum or suction.
    Type: Application
    Filed: August 9, 2021
    Publication date: February 10, 2022
    Applicant: Mitegen, LLC
    Inventors: Richard Jayne, David Closs, Benjamin A. Apker, Robert E. Thorne
  • Publication number: 20170030626
    Abstract: A cryogenic cooling manifold and methods incorporating a cryogenic cooling manifold for managing the gas layer(s) above a liquid cryogen to control cooling temperature-time profiles and ice formation for microliter and smaller samples that are plunged through the gas and into the liquid cryogen.
    Type: Application
    Filed: July 27, 2016
    Publication date: February 2, 2017
    Applicant: Mitegen, LLC
    Inventors: David Closs, Stephen Hollabaugh, Robert E. Thorne, Robert Newman, Benjamin A. Apker, Tian Xia, David Moreau