Patents by Inventor Benjamin A. MAYES

Benjamin A. MAYES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making nucleoside phosphoramidate compounds
    Patent number: 10251903
    Abstract: The present invention is directed to a process for making Nucleoside Phosphoramidate Compounds of formula (I): which are useful for the treatment and prophylaxis of HCV infection. The present invention is also directed to compounds that are useful as synthetic intermediates for making the compounds of formula (I).
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 9, 2019
    Assignees: Merck Sharp & Dohme Corp., Idenix Pharmaceuticals LLC
    Inventors: Bryon L. Simmons, Kevin R. Campos, Artis Klapars, Alistair J. Stewart, Benjamin A. Mayes, Peter E. Maligres, Alan Hyde, Steven Mark Silverman, Yong-Li Zhong, Adel M. Moussa, Kenneth Baker, Kara Van Valkenburg
  • Process for Making Nucleoside Phosphoramidate Compounds
    Publication number: 20170246198
    Abstract: The present invention is directed to a process for making Nucleoside Phosphoramidate Compounds of formula (I): which are useful for the treatment and prophylaxis of HCV infection. The present invention is also directed to compounds that are useful as synthetic intermediates for making the compounds of formula (I).
    Type: Application
    Filed: October 20, 2015
    Publication date: August 31, 2017
    Applicants: IDENIX Pharmaceuticals LLC, Merck Sharp & Dohme Corp.
    Inventors: Bryon L. SIMMONS, Kevin R. CAMPOS, Artis KLAPARS, Alistair J. STEWART, Benjamin A. MAYES, Peter E. MALIGRES, Alan HYDE, Steven Mark SILVERMAN, Yong-Li ZHONG, Adel M. MOUSSA, Kenneth BAKER, Kara van VALKENBURG
  • METHOD OF ADMINISTERING A 5,5-FUSED HETEROARYLENE HEPATITIS C VIRUS INHIBITOR FOR TREATING OF PREVENTING HEPATITIS C VIRUS INFECTION
    Publication number: 20150224085
    Abstract: Provided herein are methods of administering a 5,5-fused heteroarylene hepatitis C virus inhibitor compound or an isotopic variant thereof, or a pharmaceutically acceptable salt or solvate thereof; for treating or preventing hepatitis C virus infection in a subject.
    Type: Application
    Filed: August 29, 2013
    Publication date: August 13, 2015
    Applicant: Indenix Pharmaceuticals, Inc
    Inventors: Rahela Gasparac, Benjamin Mayes, Adel Moussa, Keith Piet-Ropaolo, John Sullivan-Bolyai, Xiao-Jian Zhou
  • Process for preparing a synthetic intermediate for preparation of branched nucleosides
    Publication number: 20070203334
    Abstract: A process is provided for the preparation of a key intermediate in the preparation of 2?-branched nucleoside compounds. The process includes contacting a protected precursor 3,4-O-isopropylidene-2-C-substituted-D-arabinono-1,5-lactone with a fluorinating agent under anhydrous conditions and converting the precursor into a protected 2-deoxy-2-halo-2-C-disubstituted ribono-1,5-lactone and optionally into a 2-deoxy-2-halo-2-C-disubstituted ribono-1,4-lactone.
    Type: Application
    Filed: December 22, 2006
    Publication date: August 30, 2007
    Inventors: Benjamin Mayes, Adel Moussa