Abstract: Provided herein are acyclic oxazepinyl compounds useful in the treatment on cancers.

Abstract: Embodiments of the present invention provide a novel system and method for TCP-to-multicast (T2M) communications. The T2M techniques may allow a client to make a single TCP connection that then fans out into communications with multiple back-end resources. Such one-to-many communications may be invisible to the client but can achieve many practical benefits.

Abstract: Systems and methods for compressing and querying data for real-time analytics. The system can receive log data and generate an intermediate representation by parsing a log template and variables from the log data into a columnar format. The method includes generating a compressed intermediate representation associated with an index type and storing the compressed intermediate representation in the columnar format based on the index type. The method includes receiving a search query and analyzing the search query to identify a user defined function. The method includes parsing the search query to convert the search query into one or more predicates that satisfy the search query. The method includes filtering the compressed log data based on the one or more predicates and providing a query result.

Abstract: Some embodiments provide a network system. The network system includes a first set of host machines for hosting virtual machines that connect to each other through a logical network. The first set of host machines includes managed forwarding elements for forwarding data between the host machines. The network system includes a second set of host machines for hosting virtualized containers that operate as gateways for forwarding data between the virtual machines and an external network. At least one of the virtualized containers peers with at least one physical router in the external network in order to advertise addresses of the virtual machines to the physical router.

Abstract: A cathode for a high voltage lithium-ion secondary battery is described, including: an electrode layer having an electrode composition containing cathode active particles, fluoropolymer binder and conductive carbon. The cathode active particles are high voltage lithium transition metal oxides, the fluoropolymer binder is a fibrillated tetrafluoroethylene polymer having high melt creep viscosity, and the conductive carbon is carbon fibers having a specific surface area of about 50 m2/g or less. The carbon fibers and the fluoropolymer binder form a conducting structural web electronically connecting the cathode active particles, enabling electronic conductivity through the electrode layer. The electrode layer is adhered to a current collector comprising aluminum having surface roughness and substantially no carbon surface coating other than the conductive carbon of the electrode layer.

Abstract: Embodiments disclosed herein provide an organic matter processing apparatus and method for the use thereof to convert organic matter into a ground and desiccated product. This can be accomplished using a bucket assembly that can grind, paddle, and heat organic matter contained therein. An algorithm is used to control the conversion of organic input to organic output by progressing through processing states based, in part, on time windows, runtimes, and sensor inputs.

Abstract: A cap logo applicator, and method of fabricating, includes a first mandrel having a front and a back, the first mandrel having a curved, non-cylindrical surface, and a relief space in the back such that when a cap is positioned on the first mandrel, a front of the cap is in contact with the non-cylindrical surface and a top of the cap extends over the relief space, and a second mandrel opposing the first mandrel and configured to apply pressure to the first mandrel. At least one of the first mandrel and the second mandrel includes a heater.

Abstract: An earphone comprising: a device housing that defines an interior cavity within the device housing; an acoustic port formed through a wall of the device housing; an audio driver disposed within the device housing and aligned to emit sound through the acoustic port; a user input region disposed along an exterior surface of the device housing; a flex circuit disposed within the interior cavity, the flex circuit including a first portion bonded at a first location to an inner surface of the device housing directly beneath the user-input region, a second portion bonded at a second location to an inner surface of the device housing spaced apart from the first location, and a third portion extending between the first and second portions; a force pixel disposed within the interior cavity and mounted to the first portion of the flex circuit below the user input region; a plurality of touch pixels disposed within the interior cavity between the force pixel and the user input region; sensor control circuitry disposed w

Abstract: The invention provides a multi-well plate reader for providing simultaneous transmission of stimulation light to, and detection of emission light from, individual wells of a multi-well plate at a plurality of distinct wavelengths.

Abstract: Embodiments disclosed herein provide an organic matter processing apparatus and method for the use thereof to convert organic matter into a ground and desiccated product. This can be accomplished using a bucket assembly that can grind, paddle, and heat organic matter contained therein. An algorithm is used to control the conversion of organic input to organic output by progressing through processing states based, in part, on time windows, runtimes, and sensor inputs.

Abstract: Aspects of this disclosure relate to a bulk acoustic wave device with a multi-layer raised frame. The bulk acoustic wave device includes a first electrode, a second electrode, a piezoelectric layer positioned between the first electrode and the second electrode, and a multi-layer raised frame structure configured to cause lateral energy leakage from a main acoustically active region of the bulk acoustic wave device to be reduced. The multi-layer raised frame structure includes a first raised frame layer embedded in the piezoelectric layer and a second raised frame layer. The first raised frame layer has a lower acoustic impedance than the piezoelectric layer.

Abstract: A portable electronic device includes a housing, a sensor array including a first camera module having a first field of view, a second camera module having a second field of view different from the first field of view, and a light source, and a rear cover formed from a glass material and defining a raised sensor array region positioned over the sensor array. The raised sensor array region defines a first hole extending through the rear cover and positioned proximate a first corner region of the raised sensor array region, and a second hole extending through the rear cover and positioned proximate a second corner region diagonal from the first corner region. The first camera module includes a first camera housing defining a recess at a corner of the first camera housing, and the second camera module includes a second camera housing extending into the recess.

Abstract: The invention provides an engineered carboxylic acid reductase (CAR) enzyme, a nucleic acid encoding the CAR enzyme, and a non-naturally occurring microbial organism comprising an exogenous nucleic acid encoding the CAR, an engineered transaminase (TA) enzyme, and/or a hexamethylenediamine (HMD) transaminase (TA2) enzyme. The invention provides a non-naturally occurring microbial organism that has a 1,6-hexanediol (HDO) pathway with a HDO pathway enzyme expressed in sufficient amounts to produce 6 aminocaproate semialdehyde, HDO, or both. The invention further provides a non-naturally occurring microbial organism that has an HMD pathway with a HMD pathway enzyme expressed in sufficient amounts to produce 6-aminocaproate semialdehyde, HMD, or both. The invention additionally provides bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO and methods for producing bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO.

Abstract: Anatomically accurate brain phantoms are physical models of brains which mimic the viscoelastic properties of brain tissues. The material used to represent different layers of the brain may be a composition of a hydrogel solution and a cross-linking agent, with ratios calculated and determined to accurately reflect the brain's mechanical properties, most notably, the viscoelasticity. Embedded sensors (e.g., accelerometers) measure impact forces and shear stresses/strains caused by a concussion-related experimental impact to the phantom. Uses of the hydrogel brain phantom include biomedical research and as a planning tool for medical treatments. A specific subject's brain may be replicated for designing personalized treatment.

Abstract: The invention provides a multi-well plate reader for providing simultaneous transmission of stimulation light to, and detection of emission light from, individual wells of a multi-well plate at a plurality of distinct wavelengths.

Abstract: A lower mandrel for a cap logo applicator includes a structure having a curved surface and a first end and a second end, an extension extending from the first end to the second end, and a first pad positioned on an upper surface of the structure. The first pad extends radially beyond both the first end and the second end and below a lower surface of the structure.

Abstract: In some embodiments, apparatuses and methods are provided herein useful to processing captured images. In some embodiments, there is provided a system for processing captured images of objects at a product storage facility including a trained machine learning model; and a control circuit. The control circuit may group a plurality of product identifiers into one or more clusters based on at least one of visual similarity of corresponding images, textual similarity of corresponding associated descriptions, and associated relationships between product identifiers of the plurality of product identifiers; determine clusters having common elements that are at least within a similarity threshold of each other; merge the clusters with the common elements; and generate a mapping dataset used to retrain the trained machine learning model to identify a plurality of objects. The mapping dataset may include a plurality of associations of associated product identifiers to a single object.