Patents by Inventor Benjamin Aaron Thuma

Benjamin Aaron Thuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitrogen-Containing Heterocyclic Compounds
    Publication number: 20250320213
    Abstract: The disclosure relates to compounds of the disclosure and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes.
    Type: Application
    Filed: April 10, 2025
    Publication date: October 16, 2025
    Applicant: Pfizer Inc.
    Inventors: Chulho Choi, Andrew Fensome, Kentaro Futatsugi, Brian Stephen Gerstenberger, Mohammad Mehdi Ghahremanpour, David Hepworth, Kevin Michael Knopf, Daniel Wei-Shung Kung, Fang-Yu Lin, Ellene Hera Mashalidis, Sarah Jane Mear, Mihir Dineshkumar Parikh, Ian Brooks Perry, Daniel Jonathan Smaltz, Jianmin Sun, Benjamin Aaron Thuma, Tao Wang, Ian William Windsor
  • Tissue-specific genome engineering using CRISPR-Cas9
    Patent number: 10851367
    Abstract: The present application provides compounds, compositions, uses thereof for the treatment of diseases, conditions and/or disorders, and uses thereof as asialoglycoprotein receptor (ASGPR) targeting agents.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: December 1, 2020
    Assignees: Pfizer Inc., The Regents of the University of California
    Inventors: Spiros Liras, Vincent Mascitti, Benjamin Aaron Thuma, Jennifer A. Doudna, Romain Rouet
  • TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9
    Publication number: 20170137801
    Abstract: The present application provides compounds, compositions, uses thereof for the treatment of diseases, conditions and/or disorders, and uses thereof as asialoglycoprotein receptor (ASGPR) targeting agents.
    Type: Application
    Filed: November 9, 2016
    Publication date: May 18, 2017
    Inventors: Spiros Liras, Vincent Mascitti, Benjamin Aaron Thuma, Jennifer A. Doudna, Romain Rouet
  • Diaryl, Dipyridinyl and Aryl-Pyridinyl Derivatives and Uses Thereof
    Publication number: 20080167371
    Abstract: Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. where R, R1, R2a, R2b, R3, R4, V, R6, R7, R8, R9, W and X are described herein.
    Type: Application
    Filed: November 13, 2007
    Publication date: July 10, 2008
    Inventors: Roger B. Ruggeri, George T. Magnus-Aryitey, Benjamin Aaron Thuma