Patents by Inventor Benjamin Alexander Mayes

Benjamin Alexander Mayes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing a synthetic intermediate for preparation of branched nucleosides
    Patent number: 7781576
    Abstract: A process is provided for the preparation of a key intermediate in the preparation of 2?-branched nucleoside compounds. The process includes contacting a protected precursor 3,4-O-isopropylidene-2-C-substituted-D-arabinono-1,5-lactone with a fluorinating agent under anhydrous conditions and converting the precursor into a protected 2-deoxy-2-halo-2-C-disubstituted ribono-1,5-lactone and optionally into a 2-deoxy-2-halo-2-C-disubstituted ribono-1,4-lactone.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: August 24, 2010
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Benjamin Alexander Mayes, Adel Moussa
  • Enantiomerically pure phosphoindoles as HIV inhibitors
    Publication number: 20080213217
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: September 28, 2007
    Publication date: September 4, 2008
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes