Patents by Inventor Benjamin Alfred William Rufus RALPH

Benjamin Alfred William Rufus RALPH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-GALACTOFURANOSE ANTIBODIES FOR DETECTING AND TREATING ASPERGILLOSIS
    Publication number: 20220089701
    Abstract: It is provided novel anti-galactofuranose antibodies and their use for diagnosis of and/or treating aspergillosis, and for the design of chimeric antigen receptor T-cells, wherein single chain variable fragment of the antibodies, such as a heavy chain variable region or a light chain variable region, is fused via a spacer and a transmembrane domain to a signaling endodomain to generate an expression cassette that will be integrated into a T cell.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 24, 2022
    Inventors: Donald Christopher SHEPPARD, Benjamin Alfred William Rufus RALPH, Todd Lambert LOWARY, Susmita SARKAR, Amira Ibrahim Aly Mohamed KHALIL
  • Anti-galactofuranose antibodies for detecting and treating aspergillosis
    Patent number: 11230594
    Abstract: It is provided novel anti-galactofuranose antibodies and their use for diagnosis of and/or treating aspergillosis, and for the design of chimeric antigen receptor T-cells, wherein single chain variable fragment of the antibodies, such as a heavy chain variable region or a light chain variable region, is fused via a spacer and a transmembrane domain to a signaling endodomain to generate an expression cassette that will be integrated into a T cell.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: January 25, 2022
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Donald Christopher Sheppard, Benjamin Alfred William Rufus Ralph, Todd Lambert Lowary, Susmita Sarkar, Amira Ibrahim Aly Mohamed Khalil
  • ANTI-GALACTOFURANOSE ANTIBODIES FOR DETECTING AND TREATING ASPERGILLOSIS
    Publication number: 20210292399
    Abstract: It is provided novel anti-galactofuranose antibodies and their use for diagnosis of and/or treating aspergillosis, and for the design of chimeric antigen receptor T-cells, wherein single chain variable fragment of the antibodies, such as a heavy chain variable region or a light chain variable region, is fused via a spacer and a transmembrane domain to a signaling endodomain to generate an expression cassette that will be integrated into a T cell.
    Type: Application
    Filed: March 23, 2020
    Publication date: September 23, 2021
    Inventors: Donald Christopher SHEPPARD, Benjamin Alfred William Rufus RALPH, Todd Lambert LOWARY, Susmita SARKAR, Amira Ibrahim Aly Mohamed KHALIL