Patents by Inventor Benjamin Anthony PRATT

Benjamin Anthony PRATT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL
    Publication number: 20260028363
    Abstract: Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and/or pharmaceuticals.
    Type: Application
    Filed: August 6, 2025
    Publication date: January 29, 2026
    Inventors: Sunny Abraham, Brant Clayton Boren, Sobhana Babu Boga, Aditya Krishnan Unni, Peter Qinhua Huang, Kevin Duane Bunker, Benjamin Anthony Pratt
  • Chiral synthesis of a tertiary alcohol
    Patent number: 12410204
    Abstract: Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and/or pharmaceuticals.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: September 9, 2025
    Assignee: Recurium IP Holdings, LLC
    Inventors: Sunny Abraham, Brant Clayton Boren, Sobhana Babu Boga, Aditya Krishnan Unni, Peter Qinhua Huang, Kevin Duane Bunker, Benjamin Anthony Pratt
  • DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS
    Publication number: 20250215010
    Abstract: Provided herein are compounds that are MMP inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating a disease, disorder or condition selected from cardiovascular disorders, lung disorders, renal disorders, hepatic disorders, and scleroderma pigmentosum.
    Type: Application
    Filed: March 29, 2023
    Publication date: July 3, 2025
    Inventors: Piotr Jakub LIPINSKI, Benjamin Anthony PRATT
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20250206753
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: October 24, 2024
    Publication date: June 26, 2025
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20250171446
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: June 27, 2024
    Publication date: May 29, 2025
    Inventors: Benjamin Anthony Pratt, Raju Mohan
  • DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS
    Publication number: 20250026761
    Abstract: Provided herein are compounds that are MMP inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating a disease, disorder or condition selected from cardiovascular disorders, lung disorders, renal disorders, hepatic disorders, and scleroderma pigmentosum.
    Type: Application
    Filed: October 7, 2022
    Publication date: January 23, 2025
    Applicant: VASA THERAPEUTICS SPÓLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA
    Inventors: Benjamin Anthony Pratt, Piotr Jakub Lipinski
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20240025914
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: May 2, 2023
    Publication date: January 25, 2024
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20230183247
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: September 16, 2022
    Publication date: June 15, 2023
    Inventors: Benjamin Anthony Pratt, Raju Mohan
  • CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL
    Publication number: 20230002426
    Abstract: Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and/or pharmaceuticals.
    Type: Application
    Filed: November 12, 2020
    Publication date: January 5, 2023
    Inventors: Sunny Abraham, Brant Clayton Boren, Sobhana Babu Boga, Aditya Krishnan Unni, Peter Qinhua Huang, Kevin Duane Bunker, Benjamin Anthony Pratt
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20230002394
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: April 19, 2022
    Publication date: January 5, 2023
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20210214362
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: November 17, 2020
    Publication date: July 15, 2021
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20210147426
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: September 18, 2020
    Publication date: May 20, 2021
    Inventors: Benjamin Anthony Pratt, Raju Mohan
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20210139490
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: September 17, 2020
    Publication date: May 13, 2021
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • FUSED BICYCLIC COMPOUNDS
    Publication number: 20200407364
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their preparation.
    Type: Application
    Filed: July 14, 2020
    Publication date: December 31, 2020
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • COMBINATION THERAPIES WITH FARNESOID X RECEPTOR (FXR) MODULATORS
    Publication number: 20200397798
    Abstract: Described herein are methods of treating a metabolic disorder in an individual in need thereof, comprising co-administering to the individual a therapeutically effective amount of an FXR modulator, and at least one second agent that is an CCR2/CCR5 antagonist, ASK1 inhibitor, DPP-IV inhibitor, caspase protease inhibitor, SGLT2 inhibitor, acetyl-CoA carboxylase (ACC) inhibitor, diacylglycerol acyltransferase-1 inhibitor, sodium-bile acid cotransporter-inhibitor, TLR-4 antagonist, PPAR alpha/delta agonist, or GLP-1 agonist, or a combination thereof.
    Type: Application
    Filed: May 25, 2017
    Publication date: December 24, 2020
    Applicant: Akarna Therapeutics, Ltd.
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20200325140
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: May 25, 2017
    Publication date: October 15, 2020
    Applicant: Akarna Therapeutics, Ltd.
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • Fused bicyclic compounds for the treatment of disease
    Patent number: 10793577
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: October 6, 2020
    Assignee: Akarna Therapeutics, Ltd.
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20200079782
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 12, 2020
    Applicant: AKARNA THERAPEUTICS, LTD.
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20190308977
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: March 15, 2019
    Publication date: October 10, 2019
    Inventors: Benjamin Anthony PRATT, Raju MOHAN
  • Fused bicyclic compounds for the treatment of disease
    Patent number: 10421759
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: September 24, 2019
    Assignee: AKARNA THERAPEUTICS, LTD.
    Inventors: Raju Mohan, Benjamin Anthony Pratt