Patents by Inventor Benjamin Auspitz

Benjamin Auspitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
    Publication number: 20120058979
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 8, 2012
    Applicant: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Patent number: 8080553
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: December 20, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • METHODS AND REAGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20100210606
    Abstract: The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: May 3, 2010
    Publication date: August 19, 2010
    Inventors: Edward Roydon Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Michael S. Slavonic, Benjamin A. Auspitz
  • Methods and reagents for the treatment of inflammatory disorders
    Patent number: 7709495
    Abstract: The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: May 4, 2010
    Assignee: CombinatoRx, Incorporated
    Inventors: Edward Roydon Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Michael S. Slavonic, Benjamin A. Auspitz
  • Methods and Reagents for the Treatment of Inflammatory Disorders
    Publication number: 20090075951
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 20, 2008
    Publication date: March 19, 2009
    Applicant: CombinatoRx, Inc.
    Inventors: Benjamin A. Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Roydon Jost-Price, Curtis T. Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael S. Slavonic, Brendan Smith, Grant R. Zimmermann
  • Anti-scarring drug combinations and use thereof
    Publication number: 20070299043
    Abstract: The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
    Type: Application
    Filed: April 4, 2007
    Publication date: December 27, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Methods, compositions, and kits for the treatment of medical conditions
    Publication number: 20070225217
    Abstract: The invention features methods, compositions, and kits for treating an immunoinflammatory disorder, an ophthalmic disorder, a musculoskeletal disorder or pain associated therewith, a periodontal disease, or a disease or condition associated with an increased serum CRP level.
    Type: Application
    Filed: November 8, 2006
    Publication date: September 27, 2007
    Applicant: CombinatoRx, Incorporated
    Inventors: Todd Chappell, Benjamin Auspitz, Edward Jost-Price
  • Anti-scarring drug combinations and use thereof
    Publication number: 20070208134
    Abstract: The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
    Type: Application
    Filed: October 3, 2006
    Publication date: September 6, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Electrical devices and anti-scarring drug combinations
    Publication number: 20070198063
    Abstract: Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring drug combination or a composition that comprises an anti-scarring drug combination to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
    Type: Application
    Filed: October 3, 2006
    Publication date: August 23, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Soft tissue implants and drug combination compositions, and use thereof
    Publication number: 20070196421
    Abstract: Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring drug combination in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
    Type: Application
    Filed: October 3, 2006
    Publication date: August 23, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Implantable sensors, implantable pumps and anti-scarring drug combinations
    Publication number: 20070197957
    Abstract: Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent or a composition that comprises an anti-scarring agent to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.
    Type: Application
    Filed: October 3, 2006
    Publication date: August 23, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Combination therapy for the treatment of immunoinflammatory disorders
    Publication number: 20070110685
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: June 16, 2006
    Publication date: May 17, 2007
    Inventors: Benjamin Auspitz, Bradley Brasher, Todd Chappell, Michael Frank, Daniel Grau, Edward Jost-Price, Seth Lederman, Palaniyandi Manivasakam, Seth Orlow, Noah Sachs, Brendan Smith
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20070010502
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 11, 2007
    Applicant: CombinatoRx Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Combinations for the treatment of inflammatory skin disorders
    Publication number: 20060100181
    Abstract: The invention features methods and compositions for the treatment of inflammatory skin conditions.
    Type: Application
    Filed: May 2, 2003
    Publication date: May 11, 2006
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Grant Zimmermann, Jason Fong, Nicole Hurst, Benjamin Auspitz, M Nichols, Curtis Keith
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20050192261
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient an antihistamine, either alone or in combination with one or more additional agents. The invention also features a pharmaceutical composition containing an antihistamine in combination with one or more additional agents.
    Type: Application
    Filed: September 14, 2004
    Publication date: September 1, 2005
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Bradley Brasher, Brendan Smith, Noah Sachs, Benjamin Auspitz, Todd Chappell, Micheal Slavonic
  • Methods and reagents for the treatment of inflammatory disorders
    Publication number: 20050187203
    Abstract: The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 19, 2004
    Publication date: August 25, 2005
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Michael Slavonic, Benjamin Auspitz
  • Methods and reagents for the treatment of inflammatory disorders
    Publication number: 20050187200
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 12, 2004
    Publication date: August 25, 2005
    Inventors: Benjamin Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael Slavonic, Brendan Smith, Grant Zimmermann
  • Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
    Publication number: 20050153947
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering an SSRI or analog or metabolite thereof and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing an SSRI or analog or metabolite thereof and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: September 20, 2004
    Publication date: July 14, 2005
    Inventors: Mahesh Padval, Edward Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Jason Fong, Benjamin Auspitz, M. Nichols, Curtis Keith, Grant Zimmerman, Bradley Brasher, Noah Sachs, Todd Chappell
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20050119160
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: October 15, 2004
    Publication date: June 2, 2005
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
    Publication number: 20040229849
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering an SSRI or analog or metabolite thereof and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing an SSRI or analog or metabolite thereof and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: February 12, 2004
    Publication date: November 18, 2004
    Inventors: Edward Roydon Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Jason Fong, Benjamin A. Auspitz, M. James Nichols, Curtis Keith, Grant R. Zimmermann, Bradley B. Brasher, Noah Sachs, Todd W. Chappell