Patents by Inventor Benjamin B. SPANGLER

Benjamin B. SPANGLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
    Publication number: 20220017559
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 22, 2021
    Publication date: January 20, 2022
    Inventors: Adam R. Renslo, Erica M.W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Cyclic peroxides as prodrugs for selective delivery of agents
    Patent number: 11014955
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: May 25, 2021
    Assignee: The Regents of the University of California
    Inventors: Adam R. Renslo, Erica M. W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
    Publication number: 20200317714
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a phannaceutically acceptable carrier.
    Type: Application
    Filed: April 8, 2020
    Publication date: October 8, 2020
    Inventors: Adam R. Renslo, Erica M.W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Cyclic peroxides as prodrugs for selective delivery of agents
    Patent number: 10662215
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: May 26, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Adam R. Renslo, Erica M. W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
    Publication number: 20190284224
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 26, 2019
    Publication date: September 19, 2019
    Inventors: Adam R. Renslo, Erica M.W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Cyclic peroxides as prodrugs for selective delivery of agents
    Patent number: 10287312
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: May 14, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Adam R. Renslo, Erica M. W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
    Publication number: 20160362439
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: February 13, 2015
    Publication date: December 15, 2016
    Inventors: Adam R. RENSLO, Erica M.W. LAUTERWASSER, Shaun D. FONTAINE, Benjamin B. SPANGLER, James A. WELLS