Patents by Inventor Benjamin B. Yellen

Benjamin B. Yellen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11420204
    Abstract: Provided herein are devices, systems, and methods for analysis of objects, such as cells. The devices, systems, and methods organize a plurality of objects in a plurality of partitions by trapping an object in a trap and transferring the object to an adjacent partition. The devices, systems, and methods provide for parallel analysis of a plurality of objects.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: August 23, 2022
    Assignee: Duke University
    Inventors: Benjamin B. Yellen, Roozbeh Abedini-Nassab, Korine A. Ohiri, David M. Murdoch, Kris Wood
  • Publication number: 20200269246
    Abstract: Provided herein are devices, systems, and methods for analysis of objects, such as cells. The devices, systems, and methods organize a plurality of objects in a plurality of partitions by trapping an object in a trap and transferring the object to an adjacent partition. The devices, systems, and methods provide for parallel analysis of a plurality of objects.
    Type: Application
    Filed: January 12, 2017
    Publication date: August 27, 2020
    Inventors: Benjamin B. Yellen, Roozbeh Abedini-Nassab, Korine A. Ohiri, David M. Murdoch, Kris Wood
  • Publication number: 20180257075
    Abstract: The current invention relates to systems for transporting, trapping, and releasing magnetically-labeled bioparticles within microfluidic environments.
    Type: Application
    Filed: August 10, 2016
    Publication date: September 13, 2018
    Inventors: Benjamin B. Yellen, David M. Murdoch, Roozbeh Abedini-Nassab, Kris C. Wood
  • Patent number: 9511368
    Abstract: A device for transporting, trapping and escaping a single biomaterial using a magnetic structure, and a method of transporting, trapping and escaping of the single biomaterial using the same are provided, and a method is provided for controlling movement and direction of the single biomaterial including soft magnetic micro structure and magnetic structure in a linear, square storage, apartment type, radial soft magnetic micro structure. Accordingly, the device for transporting, trapping and escaping a single biomaterial and the method for transporting, trapping and escaping single biomaterial using the same can control movement on the lap-on-a-chip with increased precision and ease, by using magnetic force, and thus can be advantageously used in the field of magneto-resistive sensor, or categorization of single cells or biomolecules.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: December 6, 2016
    Assignee: The Industry & Academic Cooperation in Chungnam National University (IAC)
    Inventors: Cheolgi Kim, Byeonghwa Lim, Venu Reddy, XingHao Hu, KunWoo Kim, Benjamin B. Yellen
  • Patent number: 9415398
    Abstract: One aspect of the invention provides a device for sorting non-magnetic particles. The device includes: (a) a fluid holding chamber comprising an inner and outer surface; (b) a fluid in contact with the inner surface of the fluid holding chamber, said fluid containing a dispersion of magnetic particles and at least two sets of non-magnetic particles; and (c) at least two sources of magnetic fields positioned in close proximity to, or inside of, the fluid holding chamber. The at least two sources of magnetic fields produce a changeable pattern of magnetic field minima and maxima regions thereby causing said non-magnetic particles in the fluid to be transported towards the magnetic field minima regions by magnetic force. At least one of said sources of magnetic fields comprises an array of magnetizable features on a micrometer or nanometer length scale.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: August 16, 2016
    Assignee: Drexel University
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Publication number: 20160016180
    Abstract: The present disclosure provides systems and devices for the sorting of objects using acoustic waves and magnetic forces as well as methods of using the systems and devices.
    Type: Application
    Filed: March 8, 2014
    Publication date: January 21, 2016
    Inventors: Gabriel P Lopez, Benjamin B Yellen, Lu Gao, David M. Murdoch
  • Publication number: 20150064764
    Abstract: A device for transporting, trapping and escaping a single biomaterial using a magnetic structure, and a method of transporting, trapping and escaping of the single biomaterial using the same are provided, and a method is provided for controlling movement and direction of the single biomaterial including soft magnetic micro structure and magnetic structure in a linear, square storage, apartment type, radial soft magnetic micro structure. Accordingly, the device for transporting, trapping and escaping a single biomaterial and the method for transporting, trapping and escaping single biomaterial using the same can control movement on the lap-on-a-chip with increased precision and ease, by using magnetic force, and thus can be advantageously used in the field of magneto-resistive sensor, or categorization of single cells or biomolecules.
    Type: Application
    Filed: August 29, 2013
    Publication date: March 5, 2015
    Applicant: The Industry & Academic Cooperation in Chungnam National University (IAC)
    Inventors: Cheolgi Kim, Byeonghwa Lim, Reddy Venu, Hu XingHao, KunWoo Kim, Benjamin B. Yellen
  • Publication number: 20140158600
    Abstract: One aspect of the invention provides a device for sorting non-magnetic particles. The device includes: (a) a fluid holding chamber comprising an inner and outer surface; (b) a fluid in contact with the inner surface of the fluid holding chamber, said fluid containing a dispersion of magnetic particles and at least two sets of non-magnetic particles; and (c) at least two sources of magnetic fields positioned in close proximity to, or inside of, the fluid holding chamber. The at least two sources of magnetic fields produce a changeable pattern of magnetic field minima and maxima regions thereby causing said non-magnetic particles in the fluid to be transported towards the magnetic field minima regions by magnetic force. At least one of said sources of magnetic fields comprises an array of magnetizable features on a micrometer or nanometer length scale.
    Type: Application
    Filed: February 18, 2014
    Publication date: June 12, 2014
    Applicant: Drexel University
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Patent number: 8678640
    Abstract: Device and methods for use of these devices to manipulate substantially non-magnetic particles dispersed inside a magnetic fluid by employing a changeable pattern of local magnetic field maxima and minima are provided.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: March 25, 2014
    Assignee: Drexel University
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Patent number: 8426082
    Abstract: Magnetic nanoparticle masks for lithographic applications of a substrate and methods for producing such masks via defining regions of localized magnetic field maxima and minima on a substrate are provided. Also provided are methods for producing multi-component patterns on a substrate with the magnetic nanoparticle masks.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: April 23, 2013
    Assignee: Drexel University
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Patent number: 8398295
    Abstract: Device and methods for use of these devices to manipulate substantially non-magnetic particles dispersed inside a magnetic fluid by employing a changeable pattern of local magnetic field maxima and minima are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: March 19, 2013
    Assignee: Drexel University
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Publication number: 20110086297
    Abstract: Magnetic nanoparticle masks for lithographic applications of a substrate and methods for producing such masks via defining regions of localized magnetic field maxima and minima on a substrate are provided. Also provided are methods for producing multi-component patterns on a substrate with the magnetic nanoparticle masks.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 14, 2011
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Patent number: 7838208
    Abstract: Magnetic nanoparticle masks for lithographic applications of a substrate and methods for producing such masks via defining regions of localized magnetic field maxima and minima on a substrate are provided. Also provided are methods for producing multi-component patterns on a substrate with the magnetic nanoparticle masks.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: November 23, 2010
    Assignee: Drexel University
    Inventors: Benjamin B. Yellen, Gennady Friedman
  • Publication number: 20100204674
    Abstract: A magnetic delivery system for delivering a magnetizable particle to a location in a body, the device includes a magnetizable object implanted in the body, wherein the magnetizable object includes a plurality of segments distributed throughout the magnetizable object and wherein the segments are configured to provide a magnetic gradient for attracting the magnetizable particle and an external source of a magnetic field capable of (i) magnetizing the magnetizable particle and (ii) increasing a degree of magnetization of the magnetizable object and thereby creating the magnetic gradient. A drug delivery system including the magnetic delivery system and a magnetizable particle associated with a therapeutic agent and/or a cell. A cell delivery system based on the magnetic delivery system and a magnetizable particle associated with a cell. A method of using the magnetic delivery system for delivery of a therapeutic agent and/or a cell to a targeted location in a body.
    Type: Application
    Filed: April 20, 2010
    Publication date: August 12, 2010
    Inventors: Zachary G. Forbes, Benjamin B. Yellen, Kenneth A. Barbee, Gennady Friedman
  • Patent number: 6427486
    Abstract: An articulated band of the invention is formed of a lineal array of metallic elements arranged in a repeating pattern. The elements are separably bonded to one another through magnetic forces acting therebetween. The band is characterized in that it is free of pins and other mechanical structural agents for interconnecting the band elements to one another. The configuration of the elements themselves is such that each has at least two surfaces, and such that these surfaces include one which is curved or arcuate. In a preferred embodiment of the invention, the elements include cylinders and discs which are of the same diameters. The cylinders and discs are so arranged that their axes are parallel to one another. In a closed loop configuration, the band exhibits aesthetic design features and finds use as a bracelet.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: August 6, 2002
    Inventor: Benjamin B. Yellen
  • Patent number: D438813
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: March 13, 2001
    Inventor: Benjamin B. Yellen