Patents by Inventor Benjamin Bader

Benjamin Bader has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED ISOXAZOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, METHODS OF PREPARING SAME, AND USES OF SAME
    Publication number: 20080027059
    Abstract: The invention relates to substituted isoxazolines according to the general formula (I): in which A, R1, R2, R3, R4, Z, X, m, n, and p, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted isoxazolines, to methods of preparing said substituted isoxazolines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases known to be at least in part mediated by HDAC activity or whose symptoms are known to be alleviated by HDAC inhibitors.
    Type: Application
    Filed: July 11, 2007
    Publication date: January 31, 2008
    Inventors: Dominic Brittain, Benjamin Bader, Philip Lienau, Gerhard Siemeister, Takayuki Tatamiya, Hilmar Weinmann, Christoph Huwe
  • Macrocyclic anilinopyrimidines with substituted sulphoximine as selective inhibitors of cell cycle kinases
    Publication number: 20070191393
    Abstract: The invention relates to macrocyclic anilinopyrimidines with substituted sulphoximine of the general formula I, processes for their preparation, and their use as medicaments.
    Type: Application
    Filed: January 3, 2007
    Publication date: August 16, 2007
    Inventors: Ulrich Lucking, Gerhard Siemeister, Benjamin Bader
  • Substituted imidazo[1,2b]pyridazines as kinase inhibitors, their preparation and use as medicaments
    Publication number: 20070093490
    Abstract: The invention relates to novel inhibitors of kinases, methods for preparing such inhibitors, intermediates for the preparation of such inhibitors and uses of such inhibitors.
    Type: Application
    Filed: September 1, 2006
    Publication date: April 26, 2007
    Inventors: Olaf Prien, Stuart Ince, Knut Eis, Christoph Huwe, Ulrich Lucking, Rolf Jautelat, Ulrich Zugel, Judith Gunther, Benjamin Bader, Manfred Husemann, Karina Schuck
  • Quinoline derivative, its use, production and pharmaceutical agents containing the latter
    Publication number: 20060167035
    Abstract: This invention relates to a quinoline derivative with general formula A in which R1, R2, R3, X, Y, Z and A are indicated in the description and the claims, the use of the compounds of general formula A for treating various diseases as well as the production of compounds of general formula A.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 27, 2006
    Inventors: Wolfgang Schwede, Stefan Jaroch, Benjamin Bader, Roman Hillig, Antonius Ter Laak, Dieter Zopf
  • Test system for determining the activity of cyclo-nucleotide-dependent protein kinases and vasp phosphatases
    Publication number: 20030166005
    Abstract: The invention relates to an HTS-appropriate test system for detecting the activity of cyclo-nucleotide-dependent protein kinases (cNPK) containing: a) at least one test compound; b) at least one appropriate cNPK substrate; c) at least one composition, which is to be incubated and which contains cNPK and ATP, optionally, phosphorylation reaction stoppers, and; d) an appropriate detection system for quantifying the phosphorylation of the cNPK substrate. The invention also relates to an HTS-appropriate test system for detecting the activity of VASP phosphatases containing: e) at least one test compound; f) at least one appropriate VASP phosphatase substrate; g) at least one composition, which is to be incubated and which contains VASP phosphatase, and; h) an appropriate detection system for quantifying the dephosphorylation of the VASP phosphatase substrate.
    Type: Application
    Filed: April 1, 2003
    Publication date: September 4, 2003
    Inventors: Peter Druckes, Thomas Jarchau, Ulrich Walter, Benjamin Bader