Abstract: Systems and methods for verification of the application of therapeutic energy pulses. For example, a system may include a pulse generator configured to generate energy pulses, an energy application device configured to apply the energy pulses generated by the pulse generator to a region of interest of tissue of a patient, and a verification device configured to verify the patient and/or dynamic dosing data relating to one or more characteristics associated with the application of the energy pulses to the region of interest of the tissue of the patient.

Abstract: Systems and methods for management of a distributed ledger including prescription information are disclosed. An example apparatus includes a processor and a logical data structure to configure a device according to an electronic prescription defining an action for a patient, the electronic prescription organized as record(s) in a distributed ledger and processible by the device to apply the action to the patient. The electronic prescription is to cause the device to at least: configure the device to apply the action to the patient; validate the action for the patient using the distributed ledger; and propagate a record of the action to the distributed ledger.

Abstract: Systems and methods for management of a distributed ledger including prescription information are disclosed. An example apparatus includes a processor and a logical data structure to configure a device according to an electronic prescription defining an action for a patient, the electronic prescription organized as record(s) in a distributed ledger and processible by the device to apply the action to the patient. The electronic prescription is to cause the device to at least: configure the device to apply the action to the patient; validate the action for the patient using the distributed ledger; and propagate a record of the action to the distributed ledger.

Abstract: According to some embodiments, system and methods are provided, comprising a flow module to receive one or more objectives for a flow in the production of an object; a memory for storing program instructions; a flow processor, coupled to the memory, and in communication with the flow module and operative to execute program instructions to: receive a request from a user for a current state of a flow for the object; retrieve metadata and data from the physical world associated with the object; determine a current phase in the flow for the object; select an analytic model to determine the current state of the flow for the object; instantiate a digital twin for the current phase in the flow for the object; execute the selected analytic for the instantiated digital twin; generate a response to the request including the current state of the flow for the object based on the executed analytic; and display the response on a display. Numerous other aspects are provided.

Abstract: A telescopic handle for a piece of luggage has telescoping inner and outer tubes. A rod fixed on the outer tube has a toothed lower end, a toothed upper end spaced above the toothed lower end, and an untoothed sliding section between the upper and lower ends. The outer end of the inner tube carries a grip and the outer tube is fixed in the piece of luggage. A handle on the grip can be actuated to shift a locking element in the inner tube between a locking position engaging the upper or lower end of the rod of the outer tube and preventing relative movement of the inner and outer tubes and a freeing position permitting such movement.

Abstract: The invention relates to a telescopic handle (1) for pieces of luggage, in particular travel suitcases, having an outer telescopic tube assembly (2), which is arranged on the piece of luggage in a stationary manner, an inner telescopic tube assembly (4), which can be accommodated in and pulled out of the outer telescopic tube assembly (2), and a handle part (7), which is arranged on the end (6) of the inner telescopic tube assembly (4) that can be pulled out of the outer telescopic tube assembly (2), wherein the telescopic handle (1) can be adjusted from an idle position thereof, in which the inner telescopic tube assembly (4) is accommodated in the outer telescopic tube assembly (2), to an operating position thereof, in which the inner telescopic tube assembly (4) is pulled out of the outer telescopic tube assembly (2) and the piece of luggage can be moved and steered by means of the telescopic handle (1).