Abstract: The present disclosure provides various systems, diagnostic devices, and methods for nucleic acid analysis. The systems, devices, and methods allow for the analysis of nucleic acids, in a sample, via programmable nuclease-based assays. Provided are systems comprising an instrument and a cartridge allowing for point of care use. The systems, devices, and methods described herein can be configured for multiplexed detection of nucleic acids in a single sample.

Abstract: Systems, methods and computer-readable storage media can be used to debug content items. One example method includes presenting, by a mobile application executing on a mobile device, a first application interface. The example method further includes detecting, by the mobile device, a predetermined user action. The example method further includes, in response to detecting the predetermined user action, generating debugging information from content event logs, wherein the content event logs are associated with content item slots in which content items are presented in the mobile application and presenting, by a debugging interface, the debugging information.

Abstract: A rotary impact tool including a motor housing, an electric motor supported in the motor housing, and a drive assembly for converting a continuous torque input from the motor to consecutive rotational impacts upon a workpiece. The drive assembly includes an anvil including an anvil lug, and a hammer that is both rotationally and axially movable relative to the anvil. The hammer includes a hammer lug for imparting the consecutive rotational impacts upon the anvil lug. The rotary impact tool further includes a first printed circuit board assembly including an anvil sensor, a first carrier supporting the first printed circuit board assembly, a second printed circuit board assembly including a hammer sensor, and a second carrier supporting the second printed circuit board assembly.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: A system for a vehicle having a trailer coupled thereto includes a rear gate assembly of the vehicle having a first closure panel operable between an open position and a closed position. The system also includes at least one sensor coupled to the first closure panel. The system further includes a controller that prompts execution of a security measure in response to the at least one sensor detecting a person within a predetermined proximity of at least a portion of the trailer.

Abstract: Polypeptides are provided that have activity at each of the GIP, GLP-1 and glucagon receptors. The polypeptides have structural features resulting in activity and extended duration of action at each of these receptors. Methods also are provided for treating diseases and/or conditions such as obesity, chronic weight management, type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), dyslipidemia, metabolic syndrome, Chronic Kidney Disease (CKD), osteoarthritis (OA), obesity-related sleep apnea (OSA) and polycystic ovary syndrome (PCOS).

Abstract: An apparatus for minimizing dead leg spaces in a container or tubing includes a first member having a flange for attaching the first member to a wall of the container or tubing, the flange having at least one aperture, and a second member rotatably coupled to the first member, the second member having an upper end having at least one aperture, and an open distal end. The second member is rotatable relative to the first member between a closed position where the at least one aperture of the second member is misaligned with the at least one aperture in the flange to prevent the passage of fluid, and an open position where the at least one aperture of the second member is aligned with the at least one aperture in the flange to allow for the passage of fluid.

Abstract: A method of analyzing employment-related data from a plurality of disparate systems is disclosed. The employment-related data is retrieved from the plurality of disparate systems. The plurality of disparate systems includes a human resource information system (HRIS) and an applicant tracking system (ATS). The data comprises applicant information and employee performance metrics. The retrieved data is transformed by standardizing and aggregating the data into a unified dataset based on a common semantic model that aligns definitions and formats across the disparate systems. The unified dataset is analyzed to identify trends, patterns, or correlations within the data using one or more analytical or machine learning algorithms. The unified dataset or corresponding analyses are updated in real-time through an application programming interface (API).

Abstract: A video monitoring system can include multiple collectors to receive video beacon data from multiple video monitoring interface modules. At least one beacon stream is connected to receive data from multiple collectors. A processing module receives the beacon stream and provides a real-time event stream used for real-time data analysis and a video view stream used for long-term data analysis.

Abstract: Various arrangements for integrating control of multiple cloud-based smart-home devices are presented. Registration information may be received for a first and second smart-home device that are controlled using different cloud-based server systems. A determination may be made that that the first smart-home device and the second smart-home device share a common function. The first smart-home device and the second smart-home device may be assigned to a common operating characteristic group based on the common function being shared by the first smart-home device and the second smart-home device. A control element may be provided that allows for control of smart-home devices with the common operating characteristic group. The control element may be used to control the common function.

Abstract: A method includes obtaining a plurality of entangled qubits, with high fault tolerance, represented by a lattice structure. The lattice structure includes a plurality of contiguous lattice cells. A first subset of the plurality of entangled qubits defines a first plane, and a second subset of the plurality of entangled qubits defines a second plane that is parallel to and offset from the first plane. The plurality of entangled qubits includes a defect qubit that is entangled with at least one face qubit on the first plane and at least one edge qubit on the second plane.

Abstract: A force sensor comprising a force sensitive resistor having a common electrode and an electrode array separated by a force sensitive resistor material. The sensor includes a preload structure, where the preload structure imparts a force on the force sensitive resistor material. The sensor may also include a signal conditioning board to read a signal from the electrode array and convert it to a digital output.

Abstract: Various arrangements for using captured voice to generate a custom interface controller are presented. A vocal recording from a user may be captured in which a spoken command and multiple smart-home devices are indicated. One or more common functions that map to the multiple smart-home devices may be determined. A custom interface controller may be generated that controls the one or more common functions of each smart-home device of the multiple smart-home devices.

Abstract: A method for enhancing digital imagery. The method comprises receiving a linear, intensity-based image of an environment. A histogram of intensity values is generated for a plurality of pixels within the linear, intensity-based image. Based on the histogram of intensity values, local contrast enhancement is applied to the linear, intensity-based image to generate a contrast enhanced version of the linear, intensity-based image, and artificial colorization is applied to the linear, intensity-based image to generate an artificially colorized version of the linear, intensity-based image. A composite image of the environment is then generated based on at least a portion of the contrast enhanced version of the linear, intensity-based image and at least a portion of the artificially colorized version of the linear, intensity-based image.

Abstract: A method includes obtaining a plurality of entangled qubits, with high fault tolerance, represented by a lattice structure. The lattice structure includes a plurality of contiguous lattice cells. A first subset of the plurality of entangled qubits defines a first plane, and a second subset of the plurality of entangled qubits defines a second plane that is parallel to and offset from the first plane. The plurality of entangled qubits includes a defect qubit that is entangled with at least one face qubit on the first plane and at least one edge qubit on the second plane.

Abstract: Pest-resistant polyurethane spray foam formulations and products, including building insulation, are described. The “B” side of the formulation comprises water; a polyol composition comprising one or more polyols selected from glycerin-sucrose polyols, Mannich polyols, and aromatic polyester polyols, catalyst(s); surfactant(s); a blowing agent; and 0.5 to 5 wt.%, based on the amount of spray foam formulation, of a composition comprising a capsaicin compound. Capsaicin compounds can be successfully incorporated into spray foam formulations that process well to give high- quality foams. The foams inhibit termite infestation and can help to minimize or avoid structural damage that might otherwise go undetected.

Abstract: Various arrangements for using captured voice to generate a custom interface controller are presented. A vocal recording from a user may be captured in which a spoken command and multiple smart-home devices are indicated. One or more common functions that map to the multiple smart-home devices may be determined. A custom interface controller may be generated that controls the one or more common functions of each smart-home device of the multiple smart-home devices.

Abstract: A method for enhancing digital imagery. The method comprises receiving a linear, intensity-based image of an environment. A histogram of intensity values is generated for a plurality of pixels within the linear, intensity-based image. Based on the histogram of intensity values, local contrast enhancement is applied to the linear, intensity-based image to generate a contrast enhanced version of the linear, intensity-based image, and artificial colorization is applied to the linear, intensity-based image to generate an artificially colorized version of the linear, intensity-based image. A composite image of the environment is then generated based on at least a portion of the contrast enhanced version of the linear, intensity-based image and at least a portion of the artificially colorized version of the linear, intensity-based image.

Abstract: Disclosed herein is a system for facilitating fast and intuitive investigations of security incidents by responding to physical gestures performed by security analysts within a virtual scene. A query triggers an alert for detecting security incidents that occur with respect to computing resources. Following the alert, the security analyst dons a Near-Eye-Display (NED) device and is presented with a virtual scene having control elements representing various data sets and/or data analysis operations relevant to a security incident. The security analyst investigates the security incident by performing hand motions to “grab-and-drag” control elements representing data sets. The security analyst may also perform hand motions to “tap on” control elements that represents a data analysis operation. Responsive to the hand motions, the system performs data analysis operations and displays a result within the virtual scene.

Abstract: Various arrangements for integrating control of multiple cloud-based smart-home devices are presented. Registration information may be received for a first and second smart-home device that are controlled using different cloud-based server systems. A determination may be made that that the first smart-home device and the second smart-home device share a common function. The first smart-home device and the second smart-home device may be assigned to a common operating characteristic group based on the common function being shared by the first smart-home device and the second smart-home device. A control element may be provided that allows for control of smart-home devices with the common operating characteristic group. The control element may control the common function at the first smart-home device via the first cloud-based server system and at the second smart-home device via the second cloud-based server system.