Abstract: In certain aspects, the disclosure relates to a nucleic acid molecule encoding one or more different thanotransmission polypeptides. Vectors (e.g., engineered viruses, plasmids and transposons), cells and pharmaceutical compositions comprising one or more nucleic acid molecules encoding one or more thanotransmission polypeptides are also disclosed. Methods of promoting thanotransmission by a target cell, methods of promoting an immune response in a subject, and methods of treating cancer in a subject are further disclosed.

Abstract: Generating a recipe for controlling a polishing system includes receiving a target removal profile that includes a target thickness to remove for a plurality of locations on a substrate that are angularly distributed around the substrate, and storing a first function defining a polishing rate for a zone from a plurality of pressurizable zones of a carrier head that are angularly distributed around a the carrier head. The first function defines polishing rates as a function of pressures. For each particular zone of the plurality of zones a recipe defining a pressure for the particular zone over time is calculated by calculating an expected thickness profile after polishing using the first function, and minimizing a cost function that incorporates a first term representing a difference between the expected thickness profile and a target thickness profile.

Abstract: A kit for disposing of a contaminated I.V. needle and delivering adhesive wound dressings to a patient with preferably a single gloved hand includes an adhesive mounting substrate to attach the apparatus to an available surface. An adhesive needle sheath carrier extends from the base of the apparatus for securing a needle and needle sheath for disposal following use. To the base of the apparatus are releasably adhered a wound barrier and taping strips to aid in securing a catheter to a patient. Tabs are provided on the wound barrier and taping strips to facilitate their removal from the base of the apparatus. The apparatus allows a medical technician to insert a catheter into a patient and maintain pressure on the catheter at the wound site with one hand, while disposing of the contaminated needle and then securing the catheter with wound dressings, all with preferably a single gloved other hand, thereby reducing the incidence of infection or injury.

Abstract: A kit for disposing of a contaminated I.V. needle and delivering adhesive wound dressings to a patient with preferably a single gloved hand includes an adhesive mounting substrate to attach the apparatus to an available surface. An adhesive needle sheath carrier extends from the base of the apparatus for securing a needle and needle sheath for disposal following use. To the base of the apparatus are releasably adhered a wound barrier and taping strips to aid in securing a catheter to a patient. Tabs are provided on the wound barrier and taping strips to facilitate their removal from the base of the apparatus. The apparatus allows a medical technician to insert a catheter into a patient and maintain pressure on the catheter at the wound site with one hand, while disposing of the contaminated needle and then securing the catheter with wound dressings, all with preferably a single gloved other hand, thereby reducing the incidence of infection or injury.