Abstract: Total ankle replacement (TAR) requires fixation of the tibial component to the tibia of a patient. and further requires fixation of the talar component to the talar of the patient. Disclosed herein are prosthetic implants that provide a high retention force to aid in preventing loosening after initial implantation. The prosthetic implant includes an expanding peg or post that allows the surgeon to expand the peg intraoperatively to apply radial pressure resulting in a wedged press fit that provides enhanced time zero fixation. As such. the present disclosure provides multiple fixation methods that allow for increased fixation during initial implantation of both the tibial and talar components in TAR surgery by providing dynamic compression between the prosthetic implant and the mating bone so that the prosthetic implant does not move or migrate after implantation.

Abstract: The present disclosure provides a prosthetic ankle including a talar component having a top surface and a bottom surface. The bottom surface is configured to be positioned adjacent to a talus. The top surface includes a trochlear groove extending from a posterior side of the talar component to an anterior side of the talar component. The trochlear groove includes a first portion adjacent the posterior side of the talar component and a second portion adjacent the anterior side of the talar component.

Abstract: The present disclosure provides prosthetic implants for tibial fixation in a total ankle replacement device. Methods including the devices are also disclosed.

Abstract: A system for tibial bone resection, comprising a device including a handle and a rasp coupled to the handle. The rasp includes a top surface, a bottom surface, a first side surface, and a second side surface. A portion of the top surface includes a first rough surface, a portion of the first side surface includes a second rough surface, and a portion of the second side surface includes a third rough surface. A first smooth curved surface separates the first rough surface from the second rough surface, and a second smooth curved surface separates the first rough surface from the third rough surface.

Abstract: A suture anchor assembly includes a main suture strand, a plurality of suture arms, and a plurality of suture anchor elements connected to the main suture strand by a suture arm. The suture anchor elements are configured to rest against a cortex of a bone to provide an anchor when they are in a deployed configuration. The suture anchor assemblies can be employed in place of or in addition to traditional suture anchors. The assemblies, kits, and methods described herein can be utilized in a variety of procedures and locations in the body where anchoring a graft or tissue adjacent a bone is desired, including, for example, rotator cuff repair and ligament (e.g., the anterior cruciate ligament or ACL) reconstruction and/or repair.

Abstract: A suture anchor, and a surgical filament assembly using same, capable of being fixated in a hole formed in a bone of a patient. The suture anchor preferably includes an anchor body having a distal end, a proximal end, a passage extending from the proximal end toward the distal end, at least one feature disposed on the exterior of the anchor to engage bone, and a filament knot patency element disposed within the passage and defining a channel having a sufficient minimum cross-sectional area to allow movement of a portion of a surgical filament therethrough when a removable sliding knot is formed, using the surgical filament, about the filament knot patency element. The surgical filament assembly preferably includes a first filament having a sliding knot removably positioned about the knot patency element, with a shortening limb and a tightening limb each extending from the sliding knot.

Abstract: The present invention includes compositions and methods for increasing antibiotic sensitivity and/or decreasing virulence in bacteria.

Abstract: A suture anchor assembly includes a main suture strand, a plurality of suture arms, and a plurality of suture anchor elements connected to the main suture strand by a suture arm. The suture anchor elements are configured to rest against a cortex of a bone to provide an anchor when they are in a deployed configuration. The suture anchor assemblies can be employed in place of or in addition to traditional suture anchors. The assemblies, kits, and methods described herein can be utilized in a variety of procedures and locations in the body where anchoring a graft or tissue adjacent a bone is desired, including, for example, rotator cuff repair and ligament (e.g., the anterior cruciate ligament or ACL) reconstruction and/or repair.

Abstract: A suture anchor assembly includes a main suture strand, a plurality of suture arms, and a plurality of suture anchor elements connected to the main suture strand by a suture arm. The suture anchor elements are configured to rest against a cortex of a bone to provide an anchor when they are in a deployed configuration. The suture anchor assemblies can be employed in place of or in addition to traditional suture anchors. The assemblies, kits, and methods described herein can be utilized in a variety of procedures and locations in the body where anchoring a graft or tissue adjacent a bone is desired, including, for example, rotator cuff repair and ligament (e.g., the anterior cruciate ligament or ACL) reconstruction and/or repair.

Abstract: Systems and methods of retailing a retail item to an airline passenger generally include providing an airplane equipped with: an airplane cabin; a plurality of seats disposed within the airplane cabin and partitioned by an aisle; a service cart movable along the aisle; and a digital reader device; positioning the retail item in the vicinity of the digital reader device; reading an item identifier of the retail item using the digital reader device; storing the item identifier in a reader memory of the digital reader device; positioning a digital payment object in the vicinity of the digital reader device, the digital payment object being carried onto the airplane by the airline passenger; communicating information between the digital payment object and the digital reader device; and processing payment for the retail item. The digital payment object may include a physical passenger identifier, a contactless payment object, or a portable user device.

Abstract: A push to connect fitting includes a body member adapted to receive a conduit end, a conduit comprising a first end that can be axially inserted into the body member and a conduit gripping device attached to an exterior surface of the conduit, and a retainer that retains the conduit in place when said conduit is fully inserted into the body member. Additional embodiments include providing a seal with the fitting that seals the exterior surface of the conduit, an optional load retaining sleeve for the conduit gripping device, and an optional gimbal. The push to connect aspect may be realized in the form of a single action unthreaded mechanical connection.

Abstract: A suture anchor, and a surgical filament assembly using same, capable of being fixated in a hole formed in a bone of a patient. The suture anchor preferably includes an anchor body having a distal end, a proximal end, a passage extending from the proximal end toward the distal end, at least one feature disposed on the exterior of the anchor to engage bone, and a filament knot patency element disposed within the passage and defining a channel having a sufficient minimum cross-sectional area to allow movement of a portion of a surgical filament therethrough when a removable sliding knot is formed, using the surgical filament, about the filament knot patency element. The surgical filament assembly preferably includes a first filament having a sliding knot removably positioned about the knot patency element, with a shortening limb and a tightening limb each extending from the sliding knot.

Abstract: A suture anchor, and a surgical filament assembly using same, capable of being fixated in a hole formed in a bone of a patient. The suture anchor preferably includes an anchor body having a distal end, a proximal end, a passage extending from the proximal end toward the distal end, at least one feature disposed on the exterior of the anchor to engage bone, and a filament knot patency element disposed within the passage and defining a channel having a sufficient minimum cross-sectional area to allow movement of a portion of a surgical filament therethrough when a removable sliding knot is formed, using the surgical filament, about the filament knot patency element. The surgical filament assembly preferably includes a first filament having a sliding knot removably positioned about the knot patency element, with a shortening limb and a tightening limb each extending from the sliding knot.

Abstract: A push to connect fitting includes a body member adapted to receive a conduit end, a conduit comprising a first end that can be axially inserted into the body member and a conduit gripping device attached to an exterior surface of the conduit, and a retainer that retains the conduit in place when said conduit is fully inserted into the body member. Additional embodiments include providing a seal with the fitting that seals the exterior surface of the conduit, an optional load retaining sleeve for the conduit gripping device, and an optional gimbal. The push to connect aspect may be realized in the form of a single action unthreaded mechanical connection.

Abstract: A push to connect fitting includes a body member adapted to receive a conduit end, a conduit comprising a first end that can be axially inserted into the body member and a conduit gripping device attached to an exterior surface of the conduit, and a retainer that retains the conduit in place when said conduit is fully inserted into the body member. Additional embodiments include providing a seal with the fitting that seals the exterior surface of the conduit, an optional load retaining sleeve for the conduit gripping device, and an optional gimbal. The push to connect aspect may be realized in the form of a single action unthreaded mechanical connection.

Abstract: A suture anchor assembly includes a main suture strand, a plurality of suture arms, and a plurality of suture anchor elements connected to the main suture strand by a suture arm. The suture anchor elements are configured to rest against a cortex of a bone to provide an anchor when they are in a deployed configuration. The suture anchor assemblies can be employed in place of or in addition to traditional suture anchors. The assemblies, kits, and methods described herein can be utilized in a variety of procedures and locations in the body where anchoring a graft or tissue adjacent a bone is desired, including, for example, rotator cuff repair and ligament (e.g., the anterior cruciate ligament or ACL) reconstruction and/or repair.

Abstract: The present invention includes compositions and methods of bacteriophage to increase antibiotic sensitivity in bacteria. In one aspect, the invention includes a method of increasing antibiotic sensitivity in multi-drug resistant (MDR) bacteria. Another aspect includes a pharmaceutical composition comprising a lytic bacteriophage. Yet another aspect includes a method of treating a multi-drug resistant bacterial infection in a subject. Yet another aspect includes a method of disrupting a pathogenic bacteria associated with a biofilm and compositions for use thereof.

Abstract: A suture anchor assembly includes a main suture strand, a plurality of suture arms, and a plurality of suture anchor elements connected to the main suture strand by a suture arm. The suture anchor elements are configured to rest against a cortex of a bone to provide an anchor when they are in a deployed configuration. The suture anchor assemblies can be employed in place of or in addition to traditional suture anchors. The assemblies, kits, and methods described herein can be utilized in a variety of procedures and locations in the body where anchoring a graft or tissue adjacent a bone is desired, including, for example, rotator cuff repair and ligament (e.g., the anterior cruciate ligament or ACL) reconstruction and/or repair.

Abstract: A push to connect fitting includes a body member adapted to receive a conduit end, a conduit comprising a first end that can be axially inserted into the body member and a conduit gripping device attached to an exterior surface of the conduit, and a retainer that retains the conduit in place when said conduit is fully inserted into the body member. Additional embodiments include providing a seal with the fitting that seals the exterior surface of the conduit, an optional load retaining sleeve for the conduit gripping device, and an optional gimbal. The push to connect aspect may be realized in the form of a single action unthreaded mechanical connection.

Abstract: A buckle useful for cortical fixation has a graft retention loop slidably affixed thereto for movement from a first position adjacent a first end of the buckle to a second position at about the midpoint of the buckle. The buckle, with a graft over the loop, is drawn up lengthwise through a bone tunnel through a tibia and then flipped sideways to rest against the surface of the bone with the loop and graft depending back into the tunnel. The sliding attachment of the loop permits flipping of the buckle minimizes the flipping distance, which is the excess amount of the loop which must be pulled free of the tunnel to allow the buckle to be flipped sideways.