Patents by Inventor Benjamin C. Tang

Benjamin C. Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10683379
    Abstract: Described herein are polymers, polymeric gels, or a composition thereof, for drug delivery. The polymers, which include boronic-acid containing moieties (e.g., and polyol-containing moieties (e.g., are prepared by free-radical polymerization and can self-assemble into polymeric gels such as hydrogels. Also provided are methods or preparing the polymers, kits involving the polymers and/or polymeric gels or a composition thereof, for use as materials or delivery applications of an agent to a subject.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: June 16, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Daniel Griffith Anderson, Eric Andrew Appel, Yizhou Dong, Robert S. Langer, Benjamin C. Tang, Omid Veiseh, Weiheng Wang, Matthew J. Webber, Kun Xue
  • Patent number: 9867869
    Abstract: Compounds, compositions, and methods for “smart” delivery of a therapeutic, prophylactic or diagnostic agent, such as glucose-mediated delivery of insulin through glucose-sensing insulin derivatives, are provided. The insulin derivatives bind serum albumin or agglomerate in vivo. The insulin derivatives effectively dissociate to release insulin in a hyperglycemic condition, where the complexation of glucose to a glucose-sensing element alters properties of the insulin derivative leading to the dissociation. The compounds, compositions, and methods provide a delivery strategy for both self-regulated and long-term diabetes management.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: January 16, 2018
    Assignees: Massachusetts Institute of Technology, The Children's Medical Center Corporation
    Inventors: Daniel G. Anderson, Hung-Chieh Chou, Michael J. Webber, Benjamin C. Tang, Yair Levi, Yunlong Zhang, Rosemary Lynn Kanasty, Arturo Jose Vegas, Robert S. Langer
  • Publication number: 20160280827
    Abstract: Described herein are polymers, polymeric gels, or a composition thereof, for drug delivery. The polymers, which include boronic-acid containing moieties (e.g., and polyol-containing moieties (e.g., are prepared by free-radical polymerization and can self-assemble into polymeric gels such as hydrogels. Also provided are methods or preparing the polymers, kits involving the polymers and/or polymeric gels or a composition thereof, for use as materials or delivery applications of an agent to a subject.
    Type: Application
    Filed: March 23, 2016
    Publication date: September 29, 2016
    Inventors: Daniel Griffith Anderson, Eric Andrew Appel, Yizhou Dong, Robert S. Langer, Benjamin C. Tang, Omid Veiseh, Weiheng Wang, Matthew J. Webber, Kun Xue
  • Publication number: 20150320837
    Abstract: Compounds, compositions, and methods for “smart” delivery of a therapeutic, prophylactic or diagnostic agent, such as glucose-mediated delivery of insulin through glucose-sensing insulin derivatives, are provided. The insulin derivatives bind serum albumin or agglomerate in vivo. The insulin derivatives effectively dissociate to release insulin in a hyperglycemic condition, where the complexation of glucose to a glucose-sensing element alters properties of the insulin derivative leading to the dissociation. The compounds, compositions, and methods provide a delivery strategy for both self-regulated and long-term diabetes management.
    Type: Application
    Filed: December 12, 2013
    Publication date: November 12, 2015
    Inventors: Daniel G. Anderson, Hung-Chieh Chou, Matthew J. Webber, Benjamin C. Tang, Yair Levi, Yunlong Zhang, Rosemary Lynn Kanasty, Arturo Jose Vegas, Robert A. Langer