Abstract: The invention relates to a device for locating a blood vessel of a limb of a living being, configured to be arranged substantially opposite a skin surface covering the blood vessel of said limb. According to the invention, the device comprises at least one acoustic wave transmitter configured to transmit acoustic waves, hereinafter transmitted acoustic waves, in the limb through the skin surface, at least one acoustic wave receiver configured to receive the acoustic waves reflected by the limb, hereinafter reflected acoustic waves, a module for measuring a parameter of the reflected acoustic waves or a difference in value of a parameter between the reflected acoustic waves and the transmitted acoustic waves, and a module for determining the location of the blood vessel depending on said parameter or said difference in value of said parameter.