Patents by Inventor Benjamin Chien
Benjamin Chien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240076797Abstract: A susceptor assembly for supporting a crucible during a crystal growth process includes a susceptor base, a tubular sidewall connected to the susceptor base, and a removable sacrifice ring interposed between the susceptor base and the sidewall. Each of the susceptor base and the sidewall is formed of a carbon-containing material. The susceptor base has an annular wall and a shoulder extending radially outward from an outer surface of the annular wall. The sidewall has a first end that receives the annular wall to connect the sidewall to the susceptor base. The sacrifice ring has a first surface that faces the outer surface of the annular wall, a second surface that faces an interior surface of the sidewall, and a ledge extending outward from the second surface that engages the first end of the sidewall.Type: ApplicationFiled: September 7, 2022Publication date: March 7, 2024Inventors: Hong-Huei Huang, Benjamin Michael Meyer, Chun-Sheng Wu, Wei-Chen Chou, Chen-Yi Lin, Feng-Chien Tsai
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Publication number: 20240077324Abstract: Presented are techniques of identifying, processing and displaying data point clusters associated with map information in an efficient manner Methods and systems are disclosed which process map information to identify clusters of requested data points for display, based on iterative clustering and filtering of the data points. Methods and systems are also disclosed which generate polygons representing the clusters. The amount of data to be processed and/or displayed can be reduced, without loss of any associated information content in a displayed map.Type: ApplicationFiled: November 7, 2023Publication date: March 7, 2024Inventors: Steve Chien, Mark Yinan Li, Marc Schaub, Benjamin Anderson, James Aspinall, Zhou Bailiang, Ruwen Hess
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Patent number: 10646572Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analogue formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: GrantFiled: April 5, 2019Date of Patent: May 12, 2020Assignee: Foresee Pharmaceuticals Co., Ltd.Inventors: Yuhua Li, Benjamin Chien
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Publication number: 20190231881Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analogue formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: ApplicationFiled: April 5, 2019Publication date: August 1, 2019Inventors: Yuhua LI, Benjamin CHIEN
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Patent number: 10251956Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analog formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: GrantFiled: July 27, 2017Date of Patent: April 9, 2019Assignee: Foresee Pharmaceuticals Co., Ltd.Inventors: Yuhua Li, Benjamin Chien
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Publication number: 20180050108Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analogue formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: ApplicationFiled: July 27, 2017Publication date: February 22, 2018Inventors: Yuhua Li, Benjamin Chien
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Patent number: 9744207Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analog formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: GrantFiled: January 13, 2017Date of Patent: August 29, 2017Assignee: Foresee Pharmaceuticals Co., Ltd.Inventors: Yuhua Li, Benjamin Chien
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Publication number: 20170119842Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analogue formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: ApplicationFiled: January 13, 2017Publication date: May 4, 2017Inventors: Yuhua Li, Benjamin Chien
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Patent number: 9572857Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a peptide agent formed with a strong acid that minimizes or prevents the interaction/reaction between the peptide agent and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: GrantFiled: August 6, 2016Date of Patent: February 21, 2017Assignee: Foresee Pharmaceuticals Co., Ltd.Inventors: Yuhua Li, Benjamin Chien
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Publication number: 20160331802Abstract: The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a peptide agent formed with a strong acid that minimizes or prevents the interaction/reaction between the peptide agent and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.Type: ApplicationFiled: August 6, 2016Publication date: November 17, 2016Inventors: Yuhua Li, Benjamin Chien
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Patent number: 8840915Abstract: The present invention provides methods of forming a solid, biodegradable implant in-situ in a body by administering a liquid pharmaceutical composition comprising an effective amount of a biocompatible, water-insoluble, biodegradable polymer and an effective amount of a therapeutic peptide covalently modified with one or more lipophilic or amphiphilic moieties, which are dissolved or dispersed in a biocompatible, water-soluble organic solvent. This invention also provides related compositions and methods.Type: GrantFiled: May 25, 2012Date of Patent: September 23, 2014Assignee: Foresec Pharmaceuticals, LLCInventors: Yuhua Li, Benjamin Chien
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Patent number: 8586103Abstract: The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a bioactive substance in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) an ionic complex that is formed between an amphiphilic molecule and a bioactive substance having a net charge at neutral pH in water. The present invention also provides a method of manufacturing and use of the composition thereof.Type: GrantFiled: February 5, 2009Date of Patent: November 19, 2013Assignee: Foresee Pharmaceuticals, LLCInventors: Yuhua Li, Andrew Guarino, Benjamin Chien
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Publication number: 20130254389Abstract: A method and system for reporting website activity. According to an example embodiment, the system receives event-level data representing visitor activity on a client website, infers attribution of one or more metrics to at least one navigation entity based on the visitor activity, and provides reports based on the inferred attribution.Type: ApplicationFiled: May 16, 2013Publication date: September 26, 2013Applicant: GOOGLE INC.Inventors: Jonathan Marc Heller, James Christopher Kim, Dwight Allen Merriman, Andrew Joel Erlichson, Benjamin Chien-wen Lee
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Patent number: 8452865Abstract: A method and system for reporting website activity. According to an example embodiment, the system receives event-level data representing visitor activity on a client website, infers attribution of one or more metrics to at least one navigation entity based on the visitor activity, and provides reports based on the inferred attribution.Type: GrantFiled: March 6, 2008Date of Patent: May 28, 2013Assignee: Google Inc.Inventors: Jonathan Marc Heller, James Christopher Kim, Dwight Allen Merriman, Andrew Joel Erlichson, Benjamin Chien-wen Lee
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Publication number: 20120237476Abstract: The present invention provides methods of forming a solid, biodegradable implant in-situ in a body by administering a liquid pharmaceutical composition comprising an effective amount of a biocompatible, water-insoluble, biodegradable polymer and an effective amount of a therapeutic peptide covalently modified with one or more lipophilic or amphiphilic moieties, which are dissolved or dispersed in a biocompatible, water-soluble organic solvent. This invention also provides related compositions and methods.Type: ApplicationFiled: May 25, 2012Publication date: September 20, 2012Applicant: Foressee Pharmaceuticals, LLCInventors: Yuhua LI, Benjamin CHIEN
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Patent number: 8206735Abstract: The present invention provides methods of forming a solid, biodegradable implant in-situ in a body by administering a liquid pharmaceutical composition comprising an effective amount of a biocompatible, water-insoluble, biodegradable polymer and an effective amount of a therapeutic peptide covalently modified with one or more lipophilic or amphiphilic moieties, which are dissolved or dispersed in a biocompatible, water-soluble organic solvent. This invention also provides related compositions and methods.Type: GrantFiled: July 11, 2007Date of Patent: June 26, 2012Assignee: Foresee Pharmaceuticals, LLCInventors: Yuhua Li, Benjamin Chien
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Patent number: 7964219Abstract: The present invention provides compositions and methods for the controlled release delivery of one or more biologically active compounds to a subject. Specifically, the invention provides for a pharmaceutical composition for the controlled release delivery of biologically active compounds to a subject comprising: a) a complex of a biologically active compound having at least one basic functional group and a polyanion derived from hexahydroxycyclohexane having at least two negatively charged functional groups; and b) a pharmaceutically acceptable carrier comprising a biodegradable, water-insoluble polymer. By complexing a biologically active compound with a polyanion, the tight, stable complex may be incorporated into a long-acting dosage system having a more desired drug release curve over time than that is found in the prior art. The invention also provides the methods of making such compositions and the methods of use thereof.Type: GrantFiled: August 11, 2005Date of Patent: June 21, 2011Assignee: QPS, LLCInventors: Yuhua Li, Benjamin Chien
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Publication number: 20100034801Abstract: The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a bioactive substance in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) an ionic complex that is formed between an amphiphilic molecule and a bioactive substance having a net charge at neutral pH in water. The present invention also provides a method of manufacturing and use of the composition thereof.Type: ApplicationFiled: February 5, 2009Publication date: February 11, 2010Applicant: QPS LLCInventors: Yuhua Li, Andrew Guarino, Benjamin Chien
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Publication number: 20090202481Abstract: The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a protein or peptide in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) a protein or peptide covalently conjugated with one or more formulation performance-enhancing compounds. The present invention also provides a method of manufacturing and use of the composition thereof.Type: ApplicationFiled: February 5, 2009Publication date: August 13, 2009Applicant: QPS LLCInventors: Yuhua Li, Andrew Guarino, Benjamin Chien
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Patent number: 7349827Abstract: A method and system for reporting website activity. According to an example embodiment, the system receives event-level data representing visitor activity through navigation entities on a client website, infers attribution of one or more metrics to at least one navigation entity based on the visitor activity, and provides online reports to the client based on the inferred attribution.Type: GrantFiled: September 18, 2002Date of Patent: March 25, 2008Assignee: DoubleClick Inc.Inventors: Jonathan Marc Heller, James Christopher Kim, Dwight Allen Merriman, Andrew Joel Erlichson, Benjamin Chien-wen Lee