Abstract: The present invention relates to a device for holding an interchangeable ultrasound probe for medical application. The device comprises a base comprising a fixation means arranged for fixating the device at a surface contact area of the device to a position on a patient's skin; and a base module arranged for being connected to the base and arranged for holding the ultrasound probe. The base module further comprises adjusting means arranged for adjusting the position of the ultrasound probe. The adjusting means comprises a locking mechanism arranged for fixating the adjusted position of the ultrasound probe. The base module comprises a receiver arranged for receiving and retaining the ultrasound probe, which receiver is customizable to the ultrasound probe. The invention further relates to a method.