Patents by Inventor Benjamin Clayton

Benjamin Clayton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250268847
    Abstract: This invention discloses methods and compositions for the treatment of demyelinating disorders. Specifically, the invention relates to the use guanabenz or guanabenz derivative for treating demyelinating disorders.
    Type: Application
    Filed: May 13, 2025
    Publication date: August 28, 2025
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventors: Sharon WAY, Benjamin CLAYTON, Brian POPKO
  • Patent number: 12310933
    Abstract: This invention discloses methods and compositions for the treatment of demyelinating disorders. Specifically, the invention relates to the use guanabenz or guanabenz derivative for treating demyelinating disorders.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: May 27, 2025
    Assignee: The University of Chicago
    Inventors: Sharon Way, Benjamin Clayton, Brian Popko
  • Publication number: 20210161836
    Abstract: This invention discloses methods and compositions for the treatment of demyelinating disorders. Specifically, the invention relates to the use guanabenz or guanabenz derivative for treating demyelinating disorders.
    Type: Application
    Filed: January 25, 2021
    Publication date: June 3, 2021
    Applicant: The University of Chicago
    Inventors: Sharon WAY, Benjamin CLAYTON, Brian POPKO
  • Patent number: 10905663
    Abstract: This invention discloses methods and compositions for the treatment of demyelinating disorders. Specifically, the invention relates to the use guanabenz or guanabenz derivative for treating demyelinating disorders.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: February 2, 2021
    Assignee: The University of Chicago
    Inventors: Sharon Way, Benjamin Clayton, Brian Popko
  • Patent number: 9981895
    Abstract: Composition, methods of synthesizing trans-arachidin-3; and, methods of use as a dietary supplement, food additive, pharmaceutical, nutraceutical, cosmeceutical, and antioxidant. The methods of production entail organic syntheses using primary alkylamines or primary hydroxyalkyl amines, or carboxy amines (amino acids) with natural carboxylic acids (acetic acid) as catalysts to react isovaleraldehye with trans-resveratrol. The synthesis is carried out in organic solvent, which is composed of an azeotropic mixture comprising toluene with pyridine, n-butanol, n-propanol, 2-propanol, 2-methyl-1-propanol, or other alcohols that form an azeotrope with toluene. The final product is purified and analyzed for the amount of trans-arachidin-3, such as via HPLC, IR, column chromatography, and high-performance counter-current chromatography.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: May 29, 2018
    Assignee: Parnative Inc.
    Inventors: Benjamin Clayton, Jeremy Bandy
  • Publication number: 20160015659
    Abstract: This invention discloses methods and compositions for the treatment of demyelinating disorders. Specifically, the invention relates to the use guanabenz or guanabenz derivative for treating demyelinating disorders.
    Type: Application
    Filed: March 5, 2014
    Publication date: January 21, 2016
    Applicant: UNIVERSITY OF CHICAGO
    Inventors: Sharon WAY, Benjamin CLAYTON, Brian POPKO
  • Patent number: 4197863
    Abstract: A filter for removing harmful ingredients from tobacco smoke without unduly increasing the draw having as an essential component a filter rod composed throughout of cotton fibers with substantially all of the fibers extending circumferentially of the axis of the rod. This component is combined with at least one other component positioned rearwardly of the smoke outlet and of the filter rod and this other component may be either at least one disc composed of intertangled wood cellulose or pure cotton fibers or a section of a conventional filter rod composed of cellulose acetate fibers. If at least one disc is present, it may be positioned by sandwiching it between two filter rod sections composed of cellulose acetate fibers or between one such section and the filter rod composed of cotton fibers. The entire filter assembly is closely confined within an impervious shell.
    Type: Grant
    Filed: February 27, 1976
    Date of Patent: April 15, 1980
    Inventors: Benjamin Clayton, Benjamin H. Thurman