Abstract: Methods and systems are provided for securing tissue to bone. A surgical system can include an outer shaft, an elongate inner shaft, and an implantable suture anchor assembly including first and second anchor bodies. The second, more proximal, anchor body has one or more openings extending through a side wall or through opposed side walls thereof. The inner shaft is configured to be received within the outer shaft and through the first and second anchor bodies such that a distal end of the inner shaft protrudes beyond a distal end of the first anchor body. The inner shaft is configured to be removably coupled to the first anchor body such that the inner shaft is configured to be rotated to cause a proximal portion of the first anchor body to move proximally into a lumen extending through the second anchor body and to occlude the opening in the second anchor body.

Abstract: Devices, systems, and methods for combining and/or delivering an injectable material to a patient. A first device having a first nozzle is moved rotationally and/or generally axially with respect to a second device having a first nozzle port to seat the first nozzle with respect to the first nozzle port. The second device has a nozzle pocket positioned, sized, shaped, configured, and/or dimensioned with respect to the first nozzle port to guide axial and/or rotational relative movements of the first injectable material transfer device and the second injectable material transfer device to guide the first nozzle into alignment with the first nozzle port, such as to be seated with respect to the first nozzle port.

Abstract: Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub, a multi-reservoir system, and a syringe. The multi-reservoir system may comprise a plunger assembly including a first plunger and a second plunger, a barrel portion including a housing defining a first reservoir in fluid communication with a first port and configured to contain a first constituent and a second reservoir configured to contain a second constituent and in fluid communication with a second port, and a cap including a port and a lumen extending therethrough. A third constituent may be injected from the syringe into the first reservoir via the port of the cap to form a precursor. Actuating the plunger assembly relative to the barrel portion may cause the precursor and the second constituent to be delivered into the needle hub.

Abstract: Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub and a multi-reservoir system including a plunger assembly and a barrel portion. The barrel portion may include a first lumen, a second lumen, and a plurality of channels formed in a wall of the first lumen. A first movable gasket may divide the first lumen into a first reservoir configured to contain a first constituent and a second reservoir configured to contain a second constituent. A second gasket may bound a third reservoir configured to contain a third constituent. Actuating the plunger assembly relative to the barrel portion may first cause the diluent to be injected into the second reservoir to form a precursor and then cause the precursor and the second constituent to be delivered into the needle hub.

Abstract: Devices, systems, and methods for combining and/or delivering an injectable material to a patient. A vial adaptor is configured to fluidly couple at least a first chamber and a separate chamber and to facilitate fluid exchange therebetween as well as to vent the separate chamber as material is withdrawn therefrom. The first chamber may be defined in a multi-chamber device which further defines a second chamber. The vial adaptor further defines a purge reservoir into which excess material and/or air may be purged from the second chamber. For instance, as material is ejected from the first chamber into the separate chamber, a determined amount of material may be purged from the second chamber into the purge reservoir.

Abstract: A multi-chamber device having a barrel with a first chamber and a second chamber, and a plunger assembly with a first plunger rod advanceable with respect to the first chamber and a second plunger rod advanceable with respect to the second chamber. The ends of the first and second plunger rods are independently advanceable to advance different amounts of material from the first and second chamber as the plunger assembly is advanced with respect to the barrel. The multi-chamber device may be part of a multi-chamber system including an injection system. The multi-chamber device and the injection system may include engaging elements facilitating ready coupling and decoupling of the multi-chamber device and the injection system.

Abstract: Devices, systems, and methods for combining and/or delivering an injectable material to a patient. The injectable material may be formed of two or more reactive components delivered in separate chambers. Various features are provided to reduce human error in combining the reactive components in the appropriate sequence to form the injectable material, generally at (e.g., immediately prior to) the time of delivery to a patient. The system includes a sleeve lock which facilitates coupling of a device having a first chamber containing a first component with a vial having a second chamber containing a second component to combine the first and second components. The combined first and second components are contained within the first chamber for delivery to a patient via an injection system, which may be fluidly coupled with the first chamber with the assistance of the sleeve lock.

Abstract: Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub, a multi-reservoir system, and a syringe. The multi-reservoir system may comprise a plunger assembly including a first tubular plunger and a second tubular plunger, a barrel portion including a housing defining a first reservoir in fluid communication with a first port and configured to contain a first constituent and a second annular reservoir configured to contain a second constituent and in fluid communication with a second port, and a third plunger. A third constituent may be injected from the syringe into the first reservoir to form a precursor. Actuating the plunger assembly relative to the barrel portion may cause the precursor and the second constituent to be delivered into the needle hub.

Abstract: Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub and a multi-reservoir system. The multi-reservoir system may comprise a first plunger assembly, a second plunger assembly, and a barrel portion. The first plunger assembly, the second plunger assembly, and the barrel portion may be assembled in a telescoping arrangement. Advancing the first plunger assembly may cause a first constituent to be delivered from a first reservoir of the second plunger assembly into the third reservoir to mix with a third constituent to form a precursor and a second constituent to be delivered from a second reservoir of the second plunger assembly into the fourth reservoir and advancing the first and second plunger assembly collectively causes the precursor and the second constituent to be delivered into the needle hub.

Abstract: A system includes a first cavity with an open upper proximal end and a distal end including a plurality of ports. A second cavity can be concentric with and advanceable through the open upper proximal end of the first cavity. The second cavity can include an open upper proximal end. A plunger can be on a distal end of the second cavity. The plunger can be configured to move a first constituent from the first cavity through at least one of the plurality of ports. A plunger rod can be advanceable through the open upper proximal end of the second cavity and configured to move a second constituent from the first cavity through at least one of the plurality of ports.

Abstract: A medical device includes a handle having a first end and a second end, a mixer positioned within the handle and an adapter coupled to the second end of the handle. A delivery needle includes a distal end, a proximal end, and a lumen extending from the distal end to the proximal end. The proximal end of the delivery needle is coupled to the first end of the handle. A sensor cable includes a distal end and a proximal end, and the proximal end of the sensor cable is positioned within the handle, and the distal end extends distally through the lumen of the delivery needle.

Abstract: Various devices, systems, and methods are provided for allowing surgical instruments to access a body cavity through an access device, such as a cannula. In one embodiment, a cap can be removably and replaceably coupled to a proximal end of cannula and can have an opening therethrough that communicates with an inner passageway of the cannula. Various surgical elements can be passed through the cap and cannula and into a patient when the cannula is positioned within the patient. The cap can have a side slot formed therein. The slot can be configured to allow surgical elements, such as sutures, to pass through the cap and into the cannula. At least one surgical seal can be in the cap and can be configured to receive surgical elements therethrough.

Abstract: In general, scapular tethers and methods of using scapular tethers are provided. A tether is configured to be implanted in a body of a patient and to control movement of the patient's scapula. In an exemplary embodiment, the tether is configured to be attached to at least one body structure in a patient. The tether includes a flexible member configured to, when implanted in the patient, flex in response to movement of the patient's scapula accompanying arm movement of the patient.

Abstract: A medical device includes a handle having a first end and a second end, a mixer positioned within the handle and an adapter coupled to the second end of the handle. A delivery needle includes a distal end, a proximal end, and a lumen extending from the distal end to the proximal end. The proximal end of the delivery needle is coupled to the first end of the handle. A sensor cable includes a distal end and a proximal end, and the proximal end of the sensor cable is positioned within the handle, and the distal end extends distally through the lumen of the delivery needle.

Abstract: A system includes a first cavity with an open upper proximal end and a distal end including a plurality of ports. A second cavity can be concentric with and advanceable through the open upper proximal end of the first cavity. The second cavity can include an open upper proximal end. A plunger can be on a distal end of the second cavity. The plunger can be configured to move a first constituent from the first cavity through at least one of the plurality of ports. A plunger rod can be advanceable through the open upper proximal end of the second cavity and configured to move a second constituent from the first cavity through at least one of the plurality of ports.

Abstract: Devices, systems, and methods to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more tissue augmentation constructs, which include constructs that are configured to increase a footprint across which suture applied force to tissue when the suture is tied down onto the tissue. The tissue augmentation constructs can be quickly and easily associated with the repair suture, and can be useful in many different tissue repair procedures that are disclosed in the application. Tissue augmentation constructs can include various blocks and scaffolds, among other formations. The present disclosure includes, among other disclosures, methods for using tissue augmentation scaffolds, including folding scaffolds, and descriptions and methods associated with extra-wide tissue augmentation blocks.

Abstract: Devices, systems, and methods to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more tissue augmentation constructs, which include constructs that are configured to increase a footprint across which suture applied force to tissue when the suture is tied down onto the tissue. The tissue augmentation constructs can be quickly and easily associated with the repair suture, and can be useful in many different tissue repair procedures that are disclosed in the application. In one exemplary embodiment, one or more constructs are disposed on a suture threader, which can be used to associate the construct(s) with a repair suture(s) being used to repair the soft tissue. Tissue augmentation constructs can include various blocks and patches, among other formations. Exemplary methods for manufacturing the tissue augmentation constructs are also provided.

Abstract: In general, scapular tethers and methods of using scapular tethers are provided. A tether is configured to be implanted in a body of a patient and to control movement of the patient's scapula. In an exemplary embodiment, the tether is configured to be attached to at least one body structure in a patient. The tether includes a flexible member configured to, when implanted in the patient, flex in response to movement of the patient's scapula accompanying arm movement of the patient.

Abstract: Methods and systems are provided for securing tissue to bone. A surgical system can include a driver device, an elongate shaft receivable within the driver device and having a dilator feature at its distal end, and a capture suture extending through the shaft such that the capture suture's terminal end portions extend to a more proximal position on the driver and the capture suture forms a loop that extends through an opening formed through a side of the shaft. The loop is configured to receive at least one retention suture therethrough and can be tightened by pulling the capture suture's terminal ends, thereby coupling the retention suture with the suture anchor. Once the shaft is inserted into bone and the loop with the retention suture is closed, the suture anchor is driven distally towards the dilator features and into the bone to secure the retaining suture in the bone.

Abstract: The system can include a multi-lumen chamber can removably connected to and in fluid communication with a proximal end of a mixing lumen and include a first lumen aligned with a second lumen. The first lumen can be configured to include a first constituent in a first cavity. A first plunger can be internally positioned within the first lumen to control flow of the first constituent from the first cavity into the mixing lumen. The first cavity can terminate in a first port in fluid communication with the proximal end of the mixing lumen. The second lumen can be configured to include a second constituent. A second plunger can be internally positioned within the second lumen. The second lumen can terminate in a second port adjacent the first port and in fluid communication with the proximal end of the mixing lumen.