Patents by Inventor Benjamin Cocks
Benjamin Cocks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230340569Abstract: The invention relates to a method for determining whether a subject has or is susceptible to developing a primary immunodeficiency (PID), the method comprising using a linear mixed model to fit a transcriptome profile of the subject to a PID prediction equation developed by fitting into a linear mixed model a transcriptomic relationship matrix generated from a reference set of transcriptome profiles of reference subjects with and without PID, wherein the prediction equation's result indicates whether the subject has or is susceptible to PID. The invention relates to a method for developing a primary immunodeficiency (PID) prediction equation for determining whether a subject has or is susceptible to developing a PID, the method comprising fitting into a linear mixed model a transcriptomic relationship matrix generated from a reference set of transcriptome profiles of reference subjects with and without PID to develop the PID prediction equation.Type: ApplicationFiled: February 5, 2021Publication date: October 26, 2023Inventors: Simon Green, Benjamin Cocks
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Patent number: 10456453Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: September 13, 2017Date of Patent: October 29, 2019Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, SAPUTO DAIRY AUSTRALIA PTY LIMITEDInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown, Michelle Rowney
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Publication number: 20180000908Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: ApplicationFiled: September 13, 2017Publication date: January 4, 2018Inventors: Matthew MCDONAGH, Benjamin COCKS, Angus TESTER, Peter HOBMAN, Andrew BROWN, Michelle ROWNEY
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Patent number: 9789168Abstract: The invention provides a method of treating a disorder characterized by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: July 28, 2015Date of Patent: October 17, 2017Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, Murray Goulburn Co-Operative Co., LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown, Michelle Rowney
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Patent number: 9247766Abstract: The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.Type: GrantFiled: May 14, 2009Date of Patent: February 2, 2016Assignees: Murray Goulburn Co-Operative Co., Limited, Agriculture Victoria Services Pty Ltd.Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown
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Publication number: 20160015791Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: ApplicationFiled: July 28, 2015Publication date: January 21, 2016Inventors: Matthew MCDONAGH, Benjamin COCKS, Angus TESTER, Peter HOBMAN
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Patent number: 9119818Abstract: The invention provides a method of treating a disorder characterized by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: May 14, 2009Date of Patent: September 1, 2015Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, Murray Goulburn Co-Operative Co., LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman
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Patent number: 8551547Abstract: The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, nutraceuticals and pharmaceutical comprising such angiogenin.Type: GrantFiled: November 9, 2007Date of Patent: October 8, 2013Assignees: Murray Goulburn Co-operative Co., Limited, Agriculture Victoria Services Pty Ltd.Inventors: Andrew Brown, Michelle Rowney, Peter Hobman, Matthew McDonagh, Angus Tester, Benjamin Cocks
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Publication number: 20130243728Abstract: The invention relates to a recombinant microorganism comprising a transgene encoding angiogenin and optionally follistatin, a food product, beverage product or animal feed produced from or comprising said microorganism and uses thereof.Type: ApplicationFiled: November 18, 2010Publication date: September 19, 2013Applicants: Agriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co. LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Ross Crittenden
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Patent number: 8383125Abstract: The present invention provides improved antimicrobial compositions comprising peptide fragments of tammar wallaby milk proteins and analogs and derivatives thereof exemplified by the amino acid sequences of SEQ ID Nos: 1-40 and uses therefor in the treatment of a range of infections by bacteria and fungi. The antimicrobial compositions are particularly useful for broad spectrum applications, especially for the treatment of bacterial infections.Type: GrantFiled: March 23, 2007Date of Patent: February 26, 2013Assignee: Agriculture Victoria Services Pty, LimitedInventors: Benjamin Cocks, Jianghui Wang, Jane Whitley
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Publication number: 20130039889Abstract: The invention relates to a recombinant microorganism comprising a transgene encoding angiogenin and optionally follistatin, a food product, beverage product or animal feed produced from or comprising said microorganism and uses thereof.Type: ApplicationFiled: November 18, 2011Publication date: February 14, 2013Applicants: Agriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co. LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Ross Crittenden
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Publication number: 20120331575Abstract: The invention provides a non-human transgenic animal comprising a transgene encoding angiogenin and food products comprising or obtained from the non-human transgenic animal and uses thereof.Type: ApplicationFiled: November 18, 2010Publication date: December 27, 2012Applicants: Agriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co. LimitedInventors: Peter Hobman, Matthew McDonagh, Benjamin Cocks, Angus Tester
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Publication number: 20120328591Abstract: The invention provides a method of improving the oral delivery of a therapeutic agent, comprising the step of linking the therapeutic agent to a carrier protein comprising angiogenin, fusion proteins or conjugates comprising angiogenin and a therapeutic agent and their use in medicine.Type: ApplicationFiled: November 18, 2010Publication date: December 27, 2012Applicants: AGRICULTURE VICTORIA SERVICES PTY LTD, MURRAY GOULBURN CO-OPERATIVE CO., LTD.Inventors: Matthew McDonagh, Angus Tester, Benjamin Cocks, Ross Crittenden, Jianghui Wang
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Publication number: 20110262422Abstract: The invention provides a method of treatment of any disorder in which administration of angiogenin is beneficial wherein the angiogenin is administered orally. Particularly, the oral angiogenin does not require a carrier or excipient or for the protein to be encapsulated or subjected to any other mechanism to improve its oral bioavailability.Type: ApplicationFiled: May 14, 2009Publication date: October 27, 2011Applicants: MURRAY GOULBURN CO-OPERATIVE CO., LIMITED, AGRICULTURE VICTORIA SERVICES PTY LTD.Inventors: Benjamin Cocks, Angus Tester, Peter Hobman, Matthew McDonagh
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Publication number: 20110209228Abstract: The present invention provides peptides and analogs and derivatives thereof having antimicrobial activity at least against Streptococcus uberis for the treatment of a range of infectious disease mastitis, otitis externa, clostridial intestinal disease and respiratory disease.Type: ApplicationFiled: March 13, 2009Publication date: August 25, 2011Inventors: Benjamin Cocks, German Spangenberg, Jianghui Wang
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Publication number: 20110151016Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuro-protection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: ApplicationFiled: May 14, 2009Publication date: June 23, 2011Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman
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Publication number: 20110123514Abstract: The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.Type: ApplicationFiled: May 14, 2009Publication date: May 26, 2011Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown
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Publication number: 20100136172Abstract: The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, neutraceuticals and pharmaceutical comprising such angiogenin.Type: ApplicationFiled: November 9, 2007Publication date: June 3, 2010Inventors: Andrew Brown, Michelle Rowney, Peter Hobman, Matthew McDonagh, Angus Tester, Benjamin Cocks
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Publication number: 20090312248Abstract: The present invention provides improved antimicrobial compositions comprising peptide fragments of tammar wallaby milk proteins and analogs and derivatives thereof exemplified by the amino acid sequences of SEQ ID Nos: 1-40 and uses therefor in the treatment of a range of infections by bacteria and fungi. The antimicrobial compositions are particularly useful for broad spectrum applications, especially for the treatment of bacterial infections.Type: ApplicationFiled: March 23, 2007Publication date: December 17, 2009Applicant: ARGICULTURE VICTORIA SERVICES PTY LIMITEDInventors: Benjamin Cocks, Jianghui Wang, Jane Whitley
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Publication number: 20050033018Abstract: The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.Type: ApplicationFiled: May 16, 2002Publication date: February 10, 2005Inventors: Preeti Lal, Bridget Warren, Yuming Xu, Brendan Duggan, Cynthia Honchell, Deborah Kallick, Mariah Baughn, Y. Tang, Henry Yue, Olga Bandman, Karen Jones, Shanya Becha, Uyen Tran, Janice Au-Young, Jennifer Griffin, Yeganeh Zebarjadian, Ernestie Lee, Vicki Elliott, Kavitha Thangavelu, Jayalaxmi Ramkumar, Yan Lu, April Hafalia, Narinder Chawla, Craig Ison, Michael Thornton, Anita Swarnakar, Junming Yang, Thomas Richardson, Brooke Emerling, Monique Yao, Benjamin Cocks, Bharati Sanjanwala, Patricia Mason, Ameena Gandhi, Joana Li, Rajagopal Gururajan, Kimberly Gietzen, Ian Forsythe