Abstract: An optical structure for controlling distribution of light generated by a light source is described. The optical structure includes a primary optics disposed relative to the light source and configured to reflect light generated by the light source towards a target region. The optical structure also includes a secondary optics disposed and aligned relative to the primary optics. The secondary optics is configured to at least partially block light generated by the light source from illuminating a region outside the target region.

Abstract: This invention relates to polynucleotides comprising UBE3A open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of a UBE3A gene or aberrant activity of a UBE3A gene product in the subject, such as Angelman Syndrome.

Abstract: A facility for maintaining a state of a distributed mobile app is described. The facility stores data identifying configuration options specified for configuring the distributed mobile app. The facility also stores data indicating, for each of a plurality of users of the distributed mobile app, actions taken by the user with respect to the distributed mobile app.

Abstract: A system for emitting light (such as a luminaire) includes a first light emitting diode (LED) string and a first LED driver that is electrically connected in parallel to the first LED string. The system also may include a second (or more) LED string(s), each associated with an additional LED driver. One-way conductors and normally-open switches are used so that if one LED driver fails, the remaining LED driver(s) will deliver power to the failed driver's LED string so that the light remains operational, but with a reduced brightness.

Abstract: Methods, apparatus, and articles of manufacture for observer-based landing control of a vehicle are disclosed. An example apparatus includes at least one memory, and at least one processor to execute instructions to at least in response to determining an aircraft is in a flight plan flare regime, determine an estimate state of an aircraft parameter based on an execution of a transfer function of an observer model, the execution of the transfer function based on an altitude command corresponding to the flare regime, determine a gain value based on the aircraft parameter, determine an altitude control input based on the estimate state and the gain value, determine an altitude command output based on the altitude control input and longitudinal dynamics of the aircraft, the longitudinal dynamics generated in response to the aircraft executing the altitude command output, and control an elevator of the aircraft based on the altitude command output.

Abstract: A flying drone, which includes: a fuselage composed of a single central body; wings composed of a forward aerofoil and an aft aerofoil, the aft aerofoil being offset in height and in length along the fuselage relative to the forward aerofoil; propulsion powered at least by electrical accumulators and/or photovoltaic cells; and photovoltaic cells essentially covering the upper faces of the forward aerofoil and the aft aerofoil.

Abstract: A system for controllably establishing adhesion or friction with an external body. The system comprises a channel member and an interface member. The channel member comprises fluidic channels communicating positive or negative pressure. The interface member is disposed over the channel member. The interface member comprises exposed portions and topographic members. The exposed portions are flexible and exposed to the pressure communicated by the fluidic channels. The exposed portions deform under the pressure communicated by the fluidic channels and reform in the absence of the pressure communicated by the fluidic channels. The exposed portions assume a convex shaped under positive pressure and concave shaped configuration under negative pressure. The topographic members are provided over the exposed portions. The topographic members move based on the deformation of the exposed portions. The strength of adhesion varies based on the deformation of the exposed portions.

Abstract: A swallowable device to detect sleep apnea in a patient in need thereof. The swallowable device includes an ingestible capsule. An accelerometer is contained within the ingestible capsule and is configured to reside within the stomach to detect a respiration parameter(s) indicative of sleep apnea and generate a sensing signal based thereon. The ingestible capsule also includes a radio contained within the ingestible capsule and a micro-controller unit (MCU) in electrical communication with the accelerometer and the radio and configured and programmed to receive the sensing signal. The ingestible capsule can also include a microphone to detect a respiration parameter(s) indicative of sleep apnea and/or snoring.

Abstract: Systems and methods for applying decorations from a web onto substrates are disclosed. According to some aspects, a decoration may be transferred from the web directly to a substrate based on contact of the substrate with an adhesive of a portion of the decoration while the portion of the decoration is attached to the web.

Abstract: Methods, computer program products, and apparatuses for reducing sticking during a lithography process are disclosed. An exemplary method of reducing sticking of an object to a modified surface that is used to support the object in a lithography process can include controlling a light source to deliver light to a native surface thereby causing ablation of at least a portion of the native surface to increase the roughness of the native surface thereby forming the modified surface. The increased roughness reduces the ability of the object to stick to the modified surface.

Abstract: Embodiments include assay devices within a single use, disposable cassette for biochemical assays with at least one fluid well and at least one capillary valve. The capillary valve in combination with motion of porous sheets within the assay leads to addition of liquid reagents at different times to the assay although a user adds the liquid reagents to the cassette simultaneously.

Abstract: A method for providing assistance in aiming of one or more illumination devices in an area may include, by a processor, receiving photometric data for an area, and using the photometric data to determine an aiming vector for the illumination device. The area may include the illumination device. the method may further include receiving, from an orientation sensor module of the illumination device, orientation data for the illumination device, and using the orientation data and the aiming vector to determine if there is an error in the aiming of the illumination device. The response to determining that there is an error in the aiming of the illumination device, the method further includes causing a controller associated with a driving means of the illumination device for correcting the error in the aiming of the illumination device.

Abstract: A variation testing system environment for performing variation testing of web pages and applications is disclosed. The variation testing system applies a weighted consistent hash function to user attributes of users to assign the users to a variant of a web page that is undergoing experimentation. The usage of the weighted consistent hash function allows for a stable experimental population.