Patents by Inventor Benjamin Demaree

Benjamin Demaree has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
    Publication number: 20240401124
    Abstract: The present disclosure provides materials and methods for contemporaneously analyzing genotype and phenotype from frozen specimens, the present disclosure can be extended to any biologic context where obtaining nucleic acid and protein information from single nuclei is valuable. As used herein, the method is termed nuclear DAb-seq (nDAb-seq).
    Type: Application
    Filed: October 18, 2022
    Publication date: December 5, 2024
    Inventors: Adam Abate, Harish Vasudevan, Benjamin Demaree, Cyrille L. Delley
  • PARTITIONING CELLS FOR HIGH THROUGHPUT SINGLE-CELL SEQUENCING
    Publication number: 20240254549
    Abstract: The present disclosure provides materials and methods for partitioning cells and high throughput, single-cell multi-omic sequencing. Methods for pathogen detection and identification, microbiome analysis, personalized medicine, environmental analysis where single-cell information is critical are each provided herein.
    Type: Application
    Filed: May 26, 2022
    Publication date: August 1, 2024
    Inventors: Adam Abate, Xiangpeng Li, Benjamin Demaree
  • Single Cell Genomic Sequencing Using Hydrogel Based Droplets
    Publication number: 20220033893
    Abstract: The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as “SiC-seq”, which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided.
    Type: Application
    Filed: December 21, 2017
    Publication date: February 3, 2022
    Inventors: Freeman Lan, Benjamin Demaree, Iain Clark, Adam R. Abate
  • Single cell genomic sequencing using hydrogel based droplets
    Patent number: 11124830
    Abstract: The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as “SiC-seq”, which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: September 21, 2021
    Assignee: The Regents of the University of California
    Inventors: Freeman Lan, Benjamin Demaree, Iain Clark, Adam R. Abate
  • Single Cell Genomic Sequencing Using Hydrogel Based Droplets
    Publication number: 20200277672
    Abstract: The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as “SiC-seq”, which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided.
    Type: Application
    Filed: April 15, 2020
    Publication date: September 3, 2020
    Inventors: Freeman Lan, Benjamin Demaree, Iain Clark, Adam R. Abate