Abstract: Antibodies and compositions against Claudin 6 and uses thereof are provided.

Abstract: Antibodies and compositions against Claudin 6 and uses thereof are provided.

Abstract: Antibodies and compositions against Claudin 6 and uses thereof are provided.

Abstract: Antibodies and compositions against Claudin 6 and uses thereof are provided.

Abstract: Antibodies and compositions against Claudin 6 and uses thereof are provided.

Abstract: Embodiments disclosed herein provide for antibodies, including neutralizing antibodies, against Chikungunya virus, uses thereof, and methods of identifying antibodies, including neutralizing antibodies, against Chikungunya virus. In some embodiments, antibodies that binds to a CHIKV antigen, wherein the antigen is the CHIKV E1, E2, E3 protein, or any heterocomplex thereof are provided. In some embodiments, the antibody is an isolated antibody, a neutralizing antibody, a recombinant antibody, or any combination thereof. In some embodiments, the antibodies described herein bind to an epitope of E2 Domain A, E2 Domain B, or E1 Domain II of the CHIKV antigen. In some embodiments, the antigen is E2 protein.

Abstract: Embodiments disclosed herein provide for antibodies, including neutralizing antibodies, against Chikungunya virus, uses thereof, and methods of identifying antibodies, including neutralizing antibodies, against Chikungunya virus. In some embodiments, antibodies that binds to a CHIKV antigen, wherein the antigen is the CHIKV E1, E2, E3 protein, or any heterocomplex thereof are provided. In some embodiments, the antibody is an isolated antibody, a neutralizing antibody, a recombinant antibody, or any combination thereof. In some embodiments, the antibodies described herein bind to an epitope of E2 Domain A, E2 Domain B, or E1 Domain II of the CHIKV antigen. In some embodiments, the antigen is E2 protein.

Abstract: The present invention relates to articles and methods for determining the function of genes, gene products, and nucleic acid products. The present invention also relates to identifying ligands and binding partners or proteins and nucleic acid products. The present invention also relates to methods and compositions related to reverse-transfection.

Abstract: Articles and methods are provided for determining the function of genes in a rapid and cost effective manner. Nucleic acids are arrayed upon a substrate. In accordance with certain preferred embodiments, viable cells are subsequently caused to be bound to the substrate at the locations occupied by the nucleic acids. Subsequent transduction or transfection of the cells by the nucleic acids followed by continued vitality of the cells permits expression of the proteins encoded by the respected nucleic acids. Knowledge of the identity of the nucleic acids, at least as regards their locations on the substrate, permits determination of protein function thereof. Methods of creating and using such cell-arrays, and methods of reverse-transfection and reverse-transduction are featured.

Abstract: The present invention relates to the use of lipoparticles, virus-like particles, and viruses. The present invention also relates to testing ion channel function and modulators of ion channels.

Abstract: The present invention relates to articles and methods for determining the function of genes, gene products, and nucleic acid products. The present invention also relates to identifying ligands and binding partners or proteins and nucleic acid products. The present invention also relates to methods and compositions related to reverse-transfection.

Abstract: The present invention relates to lipoparticles. The invention also relates to producing lipoparticles. The invention further relates to lipoparticles comprising a viral structural protein. The invention further relates to a lipoparticle comprising a membrane protein, and the lipoparticle can be attached to a sensor surface. The invention further relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.