Patents by Inventor Benjamin E. Low

Benjamin E. Low has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE GENERATION TARGETED GENE INTEGRATION
    Publication number: 20230287459
    Abstract: The present disclosure provides methods and compositions for high frequency, targeted mammalian transgenesis using, for example, a two-step, two-stage process that enables integrating anywhere in the mammalian genome large pieces of nucleic acid in single generation.
    Type: Application
    Filed: August 6, 2021
    Publication date: September 14, 2023
    Applicant: The Jackson Laboratory
    Inventors: Michael V. Wiles, Benjamin E. Low, Vishnu Hosur
  • HIGH FREQUENCY TARGETED ANIMAL TRANSGENESIS
    Publication number: 20220369610
    Abstract: The present disclosure provides methods and compositions for high frequency mouse transgenesis using, for example, a Bxb1 landing pad.
    Type: Application
    Filed: October 8, 2020
    Publication date: November 24, 2022
    Applicant: The Jackson Laboratory
    Inventors: Michael V. Wiles, Benjamin E. Low
  • Correction of Crb1 mutations
    Patent number: 9708629
    Abstract: Genetically engineered mice having a corrected Crb1rd8 mutation and methods for correcting the Crb1rd8 mutation to produce the genetically engineered mice are provided according to aspects of the present invention. Kits, expression vectors and fusion proteins according to aspects of the invention are provided for use to produce the genetically engineered mice characterized by a corrected Crb1rd8 mutation.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: July 18, 2017
    Assignee: The Jackson Laboratory
    Inventors: Michael V. Wiles, Benjamin E. Low
  • CORRECTION OF CRB1 MUTATIONS
    Publication number: 20140359798
    Abstract: Genetically engineered mice having a corrected Cbr1rd8 mutation and methods for correcting the Cbr1rd8 mutation to produce the genetically engineered mice are provided according to aspects of the present invention. Kits, expression vectors and fusion proteins according to aspects of the invention are provided for use to produce the genetically engineered mice characterized by a corrected Cbr1rd8 mutation.
    Type: Application
    Filed: June 3, 2014
    Publication date: December 4, 2014
    Applicant: THE JACKSON LABORATORY
    Inventors: Michael V. Wiles, Benjamin E. Low