Abstract: A system for manufacturing and using an implant for correcting a defect of a bone structure is described. In some examples, the implant includes a first surface comprising a shape configured to interface with a surface of the bone structure. In some examples, the implant includes a second surface opposite the first surface and substantially conformal to the shape of the first surface, the second surface comprising three or more point features on the second surface, wherein the three or more point features comprise a first point feature, a second point feature, and a third point feature that form nodes of a triangle, wherein each of the three or more point features are recessed below the second surface.

Abstract: Systems and methods for planning delivery of an object via a catheter, such as transseptal delivery of a prosthetic mitral valve to a patient's heart are disclosed.

Abstract: The present disclosure relates to flexible porous implant fixation systems. Certain aspects provide flexible porous structures including a helicoidal structure and a plurality of interlocking elements coupled to the helicoidal structure, the helicoidal structure being configured to connect the plurality of interlocking elements. Certain aspects provide a body comprising a porous structure, the body configured to interface with a bone perpendicular to an axis of the bone; and a screw comprising a head, wherein the head is configured to lie within a volume of the body while a portion of the screw extends away from the body, wherein the body is configured to restrict movement of the head within the body along the axis of the bone.

Abstract: A two-step approach for image segmentation during the treatment planning process is disclosed. In a first step, an automatic segmentation method can be used to generate a first, provisional segmentation. The first, provisional segmentation may be generated using fast, but less accurate segmentation methods. The first provisional segmentation may be used to generate a default treatment plan for approval. Once the default treatment plan is approved, a more robust, second image segmentation may be performed. The second segmentation may be used to design patient-specific devices that can be used to deliver the patient-specific medical treatment.

Abstract: The implant fixation systems disclosed herein include an implant manufactured with, or coupled to, one or more implant fixation devices used to secure the implant to bone. Various implant fixation device embodiments have an engagement element with a concave engagement tip, a guiding element defining a planned trajectory along which the engagement element is configured to move, and an adjustment element configured to move the engagement element along the planned trajectory. Moving the engagement element along the planned trajectory causes the concave engagement tip to enter a bone in a first position and rotate within the bone to a second position. Continuing to move the engagement element along the planned trajectory may cause the concave engagement tip to undergo translational movement from the second position to a third position, thereby pulling the implant towards the bone and exerting compression forces on the bone.

Abstract: The present application relates to adaptive surface surgical guiding apparatuses. A surgical guiding apparatus may include one or more rigid portions configured to attach to a first region of an underlying anatomical surface. The surgical guiding apparatus may further include a variable deformable portion coupled to the one or more rigid portions, the variable deformable portion configured to conform to a shape of a second region of the underlying anatomical surface to provide a stable attachment of the surgical guiding apparatus to the underlying anatomical surface. The present disclosure further provides methods for manufacturing surgical guiding apparatuses and uses of the apparatuses for placement onto an underlying anatomical surface.

Abstract: The present application relates to adaptive surface surgical guiding apparatuses, tools, devices, or guides including stability and/or verification elements for use in surgical applications. In one embodiment, a surgical guiding apparatus comprises one or more rigid portions configured to attach to a first region of an underlying anatomical surface; a variable deformable portion coupled to the one or more rigid portions, the variable deformable portion configured to conform to a shape of a second region of the underlying anatomical surface; and a soft-tissue piercing element configured to pierce soft-tissue overlying a third region of the underlying anatomical surface and to attach to the underlying anatomical surface.

Abstract: A two-step approach for image segmentation during the treatment planning process is disclosed. In a first step, an automatic segmentation method can be used to generate a first, provisional segmentation. The first, provisional segmentation may be generated using fast, but less accurate segmentation methods. The first provisional segmentation may be used to generate a default treatment plan for approval. Once the default treatment plan is approved, a more robust, second image segmentation may be performed. The second segmentation may be used to design patient-specific devices that can be used to deliver the patient-specific medical treatment.

Abstract: Provided herein is a method for generating and manufacturing a surgical guide for guiding a surgical intervention on a bone of a patient, and surgical guides obtainable by said method. The guides provided herein comprise an anatomy engagement surface or contact points for contacting with the first bone, and further comprise a support surface configured for contacting a second bone of the patient, over a certain range of motion of said second bone.

Abstract: Described herein are guiding instruments for use in surgical procedures involving the positioning of a bone plate. Furthermore methods for the manufacture of such instruments and methods for positioning a bone plate are also provided.

Abstract: The present application relates to adaptive surface surgical guiding apparatuses, tools, devices, or guides including stability and/or verification elements for use in surgical applications. In one embodiment, a surgical guiding apparatus comprises one or more rigid portions configured to attach to a first region of an underlying anatomical surface; a variable deformable portion coupled to the one or more rigid portions, the variable deformable portion configured to conform to a shape of a second region of the underlying anatomical surface; and a soft-tissue piercing element configured to pierce soft-tissue overlying a third region of the underlying anatomical surface and to attach to the underlying anatomical surface.

Abstract: The implant fixation systems disclosed herein include an implant manufactured with, or coupled to, one or more implant fixation devices used to secure the implant to bone. Various implant fixation device embodiments have an engagement element with a concave engagement tip, a guiding element defining a planned trajectory along which the engagement element is configured to move, and an adjustment element configured to move the engagement element along the planned trajectory. Moving the engagement element along the planned trajectory causes the concave engagement tip to enter a bone in a first position and rotate within the bone to a second position. Continuing to move the engagement element along the planned trajectory may cause the concave engagement tip to undergo translational movement from the second position to a third position, thereby pulling the implant towards the bone and exerting compression forces on the bone.

Abstract: The invention relates to guiding instruments (1) for guiding an acetabular cup implant as well as to impactors (13) for press-fitting an acetabular cup implant, both of which are of use during reconstructive joint surgery, more specifically during reconstructive hip joint surgery. The guiding instruments are characterized in that they fit onto an acetabular cup implant (8) and are designed to fit onto specific areas of the pelvic bone ensuring a unique fit on the bone. The impactors are characterized in that a fixation element (15) is connected to the stem (14) of the impactor by a ball joint. The invention also relates to combined guiding and fitting elements for an acetabular cup implant, comprising a guiding instrument and an impactor.

Abstract: Provided herein is a method for generating and manufacturing a surgical guide for guiding a surgical intervention on a bone of a patient, and surgical guides obtainable by said method.

Abstract: The present invention relates to guiding instruments for acetabular cup reamers, which allow for a much more accurate and precise reaming of the acetabular implant zone. The invention further provides combinations of acetabular cup reamers and guiding instruments therefor and methods for their manufacture and their use.

Abstract: Described herein are guiding instruments for use in surgical procedures involving the positioning of a bone plate. Furthermore methods for the manufacture of such instruments and methods for positioning a bone plate are also provided.

Abstract: The present invention relates to guiding instruments for acetabular cup reamers, which allow for a much more accurate and precise reaming of the acetabular implant zone.

Abstract: The invention relates to guiding instruments (1) for guiding an acetabular cup implant as well as to impactors (13) for press-fitting an acetabular cup implant, both of which are of use during reconstructive joint surgery, more specifically during reconstructive hip joint surgery. The guiding instruments are characterized in that they fit onto an acetabular cup implant (8) and are designed to fit onto specific areas of the pelvic bone ensuring a unique fit on the bone. The impactors are characterized in that a fixation element (15) is connected to the stem (14) of the impactor by a ball joint. The invention also relates to combined guiding and fitting elements for an acetabular cup implant, comprising a guiding instrument and an impactor.