Patents by Inventor Benjamin Grant

Benjamin Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH PRECISION SPECTRAL FRET ASSAYS
    Publication number: 20210255195
    Abstract: Provided herein are methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. In one embodiment, the method includes providing a target protein, where the target protein includes two heterologous domains, each domain having chromophores that together act as a FRET pair. In another embodiment, the method includes providing a target protein and a second protein, wherein the target protein includes a first heterologous domain including a chromophore, and the second protein includes a second heterologous domain including a chromophore, where the chromophores together act as a FRET pair. The method further includes contacting a sample including the target protein and optional second protein with a test compound to form a mixture, and measuring a fluorescence emission spectrum of the mixture during exposure to a light source.
    Type: Application
    Filed: January 18, 2021
    Publication date: August 19, 2021
    Inventors: Tory M. Schaaf, David D. Thomas, Benjamin Grant, Kurt C. Peterson, Gregory D. Gillispie
  • HIGH PRECISION SPECTRAL FRET ASSAYS
    Publication number: 20190353663
    Abstract: Provided herein are methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. In one embodiment, the method includes providing a target protein, where the target protein includes two heterologous domains, each domain having chromophores that together act as a FRET pair. In another embodiment, the method includes providing a target protein and a second protein, wherein the target protein includes a first heterologous domain including a chromophore, and the second protein includes a second heterologous domain including a chromophore, where the chromophores together act as a FRET pair. The method further includes contacting a sample including the target protein and optional second protein with a test compound to form a mixture, and measuring a fluorescence emission spectrum of the mixture during exposure to a light source.
    Type: Application
    Filed: January 25, 2018
    Publication date: November 21, 2019
    Inventors: Tory M. Schaaf, David D. Thomas, Benjamin Grant, Kurt C. Peterson, Gregory D. Gillispie
  • HIGH PRECISION SPECTRAL FRET ASSAYS
    Publication number: 20180238901
    Abstract: Provided herein are methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. In one embodiment, the method includes providing a target protein, where the target protein includes two heterologous domains, each domain having chromophores that together act as a FRET pair. In another embodiment, the method includes providing a target protein and a second protein, wherein the target protein includes a first heterologous domain including a chromophore, and the second protein includes a second heterologous domain including a chromophore, where the chromophores together act as a FRET pair. The method further includes contacting a sample including the target protein and optional second protein with a test compound to form a mixture, and measuring a fluorescence emission spectrum of the mixture during exposure to a light source.
    Type: Application
    Filed: January 25, 2018
    Publication date: August 23, 2018
    Inventors: Tory M. Schaaf, David D. Thomas, Benjamin Grant, Kurt C. Peterson, Gregory D. Gillispie
  • Walker for improved stairway mobility
    Patent number: 8820338
    Abstract: A walker adapted to navigate stairways and inclined surfaces is provided.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: September 2, 2014
    Inventors: Thomas Catricala, Benjamin Grant, Griffin Latulippe, Alexander Mutchler, Purven Parikh, Charles Persaud, Matthew Wilson, Matthew Thomas, Jeffrey Epp