Abstract: The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use thereof.

Abstract: The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use thereof.

Abstract: The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use thereof.

Abstract: The present invention provides compositions for RNA interference and methods of use thereof. In particular, the invention provides single-stranded small interfering RNAs. Functional and genomic and proteomic methods are featured. Therapeutic methods are also featured.

Abstract: The present invention provides compositions for RNA interference and methods of use thereof. In particular, the invention provides single-stranded small interfering RNAs. Functional and genomic and proteomic methods are featured. Therapeutic methods are also featured.

Abstract: The present invention provides compositions for RNA interference and methods of use thereof. In particular, the invention provides single-stranded small interfering RNAs. Functional and genomic and proteomic methods are featured. Therapeutic methods are also featured.

Abstract: A method for a service monitor of a computing environment includes monitoring application network transactions and behaviors for the computing environment, the computing environment including client subnets accessing servers, the monitoring independent of client site monitors; decomposing the monitored transactions and behaviors into network, server and application quality components; using the components to identify services, servers and client subnets as associated with a quality issue; and implementing an active investigation on the services, servers and client subnets to gather statistical data to assist root cause analysis independent of a network monitoring interruption; The quality issue might be a performance issue, such as excessive response times, excessive loss rates, or small transfer rates. The quality issue might be an availability issue, such as an unreachable network node or a missing web page.

Abstract: The present invention provides compositions for RNA interference and methods of use thereof. In particular, the invention provides single-stranded small interfering RNAs. Functional and genomic and proteomic methods are featured. Therapeutic methods are also featured.

Abstract: A fastener for a reverse fed panelboard circuit breaker is taught. Briefly stated, a resilently deformable pivoting member is disposed between side barrier fins in a two pole panelboard breaker. A pin at one end of the fastener is placed through a screw hole which is contained in the panelboard and disposed between the side barriers of the panelboard breaker, with the fastener rotatably urged towards the breaker so as to, when fully rotated causes the breaker retention tab to be urged against the panelboard retention hook and also for the fastener to lay against and come in contact with the edge of the panelboard breaker thereby preventing removal of the breaker without first removing the fastener.