Abstract: Recombinant microorganisms configured for enhanced production of carotenoids and other compounds and methods of using the recombinant microorganisms for the production of same. The recombinant microorganism can include a modification that decreases phytoene synthase (CrtB) activity, a modification that decreases lycopene-forming phytoene desaturase (CrtI) activity, a modification that decreases lycopene cyclase (CrtY) activity, a modification that decreases beta-carotene hydroxylase (CrtZ) activity, a modification that decreases 2,2?-beta hydroxylase (CrtG) activity, and/or a modification that increases beta-carotene ketolase (CrtW) activity. The recombinant microorganism can be from the genus Novosphingobium, such as Novosphingobium aromaticivorans.

Abstract: Various embodiments and methods for improved joint repair are disclosed. At least some of the embodiments may include an adjustable loop construct with at least one anchor. At least some of the embodiments may include an all-suture anchor. At least some of the embodiments may include an adjustable loop construct with a locking passage. Embodiments may implement a method that reduces or avoids material removal from the bones of the joint. Embodiments may include means to reduce elongation of the repair over time.

Abstract: Recombinant microorganisms that catabolize lignin aromatics, such as acetovanillone, and methods of using same to catabolize the lignin aromatics.

Abstract: The present disclosure relates to a door leaf formed of a flexible material, wherein the flexible material is resistant to puncture and resistant to tearing; and to a door system comprising the door leaf.

Abstract: The present disclosure relates to a door leaf formed of a flexible material, wherein the flexible material is resistant to puncture and resistant to tearing; and to a door system comprising the door leaf.

Abstract: The present disclosure relates to a door leaf formed of a flexible material, wherein the flexible material is resistant to puncture and resistant to tearing; and to a door system comprising the door leaf.

Abstract: A tissue repair assembly is disclosed, including a soft anchor body and at least a first suture operably coupled to the anchor body. Tensioning on first and/or second ends of first suture may deploy the anchor body to a second configuration, in which the anchor body is axially compressed and radially extended. The tissue repair assembly may also include a means to cinch around a portion of a first and/or second suture and knotlessly lock the tissue repair assembly. Some embodiments may include a pre-formed knot. In some embodiments, the preformed knot may be a nail knot, provided wrapped around an insertion instrument and configured to receive and cinch around a suture extending therethrough.

Abstract: A novel implementation of particle swarm optimization termed Recursive Hierarchical Particle Swarm Optimization (RHPSO) is presented. An improved method for optimizing a complex solution space for any given mathematical function, where the mathematical function may be 1) finding optimal parameters such as topology, security, and routing in distributed/networked systems; 2) finding optimal frequency and channel assignments for telecommunication networks; and 3) code-breaking, searching a large solution space of ciphers for the one correct decryption.

Abstract: A novel implementation of particle swarm optimization termed Recursive Hierarchical Particle Swarm Optimization (RHPSO) is presented. An improved method for optimizing a complex solution space for any given mathematical function, where the mathematical function may be 1) finding optimal parameters such as topology, security, and routing in distributed/networked systems; 2) finding optimal frequency and channel assignments for telecommunication networks; and 3) code-breaking, searching a large solution space of ciphers for the one correct decryption.

Abstract: A novel implementation of particle swarm optimization termed Recursive Hierarchical Particle Swarm Optimization (RHPSO) is presented. An improved method for optimizing a complex solution space for any given mathematical function, where the mathematical function may be 1) finding optimal parameters such as topology, security, and routing in distributed/networked systems; 2) finding optimal frequency and channel assignments for telecommunication networks; and 3) code-breaking, searching a large solution space of ciphers for the one correct decryption.

Abstract: The present disclosure relates to a hand towel dispenser. The hand towel dispenser comprises: an opening for accessing hand towels stored in the dispenser: an inner surface extending from the opening, wherein the inner surface defines an internal cavity within the dispenser for storing hand towels, and wherein the inner surface is substantially free from surface undulations such that the cavity comprises substantially no ligature points: and a plurality of flexible tabs located at the opening, the tabs arranged to retain hand towels within the cavity.

Abstract: A device for controlling the flow of a fluid through a conduit from an upstream side of the device to a downstream side of the device. The device includes a housing defining a valve aperture and a mounting member arranged on the downstream side of the valve aperture. A valve member is movably mounted on the mounting member and is arranged to selectively open and close the valve aperture to control the flow of fluid. A soft seal is arranged on the housing for substantially sealing the valve aperture when the valve member contacts the housing. The soft seal is located downstream of a convex curved surface of the housing which is shaped to separate the flow of fluid through the valve aperture away from the surface of the housing such that the fluid does not impinge directly on the soft seal.

Abstract: The present disclosure relates to a hand rail. The hand rail comprises an elongate handle and an attachment portion, the handle being connected to the attachment portion by a continuous connecting web that extends from a first end of the hand rail to a second end of the hand rail to define an elongate channel between the handle and the attachment portion, the channel being open at the first end of the handle and closed at the second end of the handle; wherein a base of the channel is sloped relative to the handle such that liquid drains out of the channel when the handle is in a horizontal orientation.

Abstract: Disclosed herein is a safety device for attachment at an edge of a door leaf. The safety device comprises a pressure monitor and an electromagnetic lock element. The pressure monitor is configured, in response to a force being applied to the safety device, to issue a signal.

Abstract: A novel implementation of particle swarm optimization termed Recursive Hierarchical Particle Swarm Optimization (RHPSO) is presented. An improved method for optimizing a complex solution space for any given mathematical function, where the mathematical function may be 1) finding optimal parameters such as topology, security, and routing in distributed/networked systems; 2) finding optimal frequency and channel assignments for telecommunication networks; and 3) code-breaking, searching a large solution space of ciphers for the one correct decryption.

Abstract: A door system for fitting to a wall is disclosed, the door system comprising a first frame portion and a second frame portion to which a door leaf is attached, wherein the door leaf comprises an anti-ligature device. The second frame portion is configured to slidingly engage with the first frame portion between first and second limit positions such that the door system can accommodate a variety of wall thicknesses.

Abstract: A lock for installation in a door leaf defining a first plane, the lock comprising: a housing; and a bolt moveable relative to the housing between a retracted position, and an extended position in which a distal portion of the bolt protrudes from an opening in the shoulder sloped in a plane parallel to the first plane, such that the bolt housing; wherein the distal portion of the bolt comprises at least one is moveable into the retracted position in response to a force applied to the shoulder.

Abstract: Various embodiments and methods for improved joint repair are disclosed. At least some of the embodiments may include an adjustable loop construct with at least one anchor. At least some of the embodiments may include an all-suture anchor. At least some of the embodiments may include an adjustable loop construct with a locking passage. Embodiments may implement a method that reduces or avoids material removal from the bones of the joint. Embodiments may include means to reduce elongation of the repair over time.