Abstract: A lab-on-chip platform is provided and includes a substrate. The substrate includes a microfluidic path. The microfluidic path has multiple inputs and an output and an analysis area downstream from a mixing area. The lab-on-chip platform further includes a cover disposed on the substrate to partially enclose the microfluidic path, a mineral layer deposited in at least the mixing area and obstructions. The mineral layer is configured to at least partially chemically react with fluid within the microfluidic path to form at least first particles and second particles, which are substantially smaller than the first particles. The obstructions are formed or disposed in the analysis area and configured to capture the first particles in the analysis area and to allow the second particles and unreacted fluid to pass out of the analysis area.

Abstract: A method, system, and computer program product are provided for monitoring neuron growth within a lattice and stopping a spread of an infection. An infection visual recognition module monitors and captures images of the lattice during the neuron growth. The presence of the infection in the neurons within the lattice is identified. The identifying includes performing, via a deep neural network, visual recognition on the captured images to identify the presence of the infection. In response to the identifying, applying a laser to the infected area of the lattice with sufficient energy for stopping the infection. The lattice is flushed to remove chemical byproducts and dead cells resulting from the laser application.

Abstract: A modular flooring system is disclosed to accommodate non-planar configurations of modular floor mats. Modular mats each have a main central portion and overhanging and underhanging flanges extending therefrom. The outer surfaces of the mats have treads formed thereon, which may be of different grades, such as industrial or pedestrian grade. Each flange contains a plurality of bores, each comprising a recess at opposing mat surfaces connected by a central portion. The recess depth at one mat surface differs from the recess depth at the opposing surface, creating an offset spacing to account for surface tread regardless of mat overlay and configuration. A fastener, having a head and opposite foot, is inserted through aligned bores in adjacent mats and rotated to lock or unlock mats in each configuration. The modular flooring system provides increased utility through enabling planar, stacked, and stepped configurations of the system.

Abstract: An apparatus for enriching a target gas from a gas mixture. The apparatus includes a cascading series of parallel arrangements of a plurality of gas separator cells. The gas separator cells of a second stage receive the output of gas separator cells of a prior stage as input. A gas separator cell includes an input portion, and a depleted gas outlet that is fed to an input of another gas separator cell or fed back to upstream stages. The outlet of a current stage connects to an input inlet of a subsequent stage. The input and output portions of the gas separator cell connect to form a chamber formed by connection of the input portion and the output portion and which includes a gas permeable membrane, selective to a target gas. The gas separator cell includes a gas permeable material supporting the gas permeable membrane.

Abstract: A system may comprise a heat spreader with a sample holder, an amine solution in the sample holder; a temperature sensor configured to measure a temperature of the amine solution; a heating and cooling device in the spreader, a gas flow valve connected to a gas inlet tube, wherein an end of the gas inlet tube sits below a surface level of the amine solution; and a CO2 (carbon dioxide) sensor connected to a gas outlet tube.

Abstract: A composition for carbon dioxide (CO2) capture includes 2-aminocyclohexanol, cis-1,2-diaminocyclohexane, meglumine, or combinations thereof. A process of CO2 capture includes mixing a CO2-containing gas with the composition. A system includes a component for receiving a gas and the composition, which absorbs CO2 from the gas. A further composition includes a first amine solvent selected from 2-aminocyclohexanol, cis-1,2-diaminocyclohexane, and meglumine and a second amine solvent independently selected from 2-aminocyclohexanol, cis-1,2-diaminocyclohexane, meglumine, ethyl diethanolamine, dimethylethanolamine, piperidine, 2-amino-2-methyl-1-propanol, and monoethanolamine. A further process includes reacting CO2 with an amine selected from 2-aminocyclohexanol, cis-1,2-diaminocyclohexane, and meglumine.

Abstract: A method of forming a microfluidic device is disclosed. The method includes forming a first dielectric layer on a substrate, forming electrodes partially into the first dielectric layer, and forming a second dielectric layer on the electrodes. The method includes filling, with a metal material, two wells formed in the second dielectric layer such that the metal material is in direct contact with the electrodes. The method includes forming a third dielectric layer on the metal material and second dielectric layer. The method includes filling, with a structural material, a channel formed between the wells such that the structural material does not directly contact the electrodes. The method includes forming a fourth dielectric layer on the third dielectric layer and the structural material, extracting the structural material through at least one vent hole in the fourth dielectric layer, and forming a fifth dielectric layer on the fourth dielectric layer.

Abstract: A neural lattice device includes a substrate having formed therein one or more wells and one or more supply ducts. A channel network includes one or more channels configured to establish fluid communication among the at least one well and the at least one supply duct. A reservoir is coupled to the substrate and configured to hold a fluid, and a cover is disposed against an upper surface of the substrate and configured to hermetically seal the wells, the supply ducts and the channel network.

Abstract: A structure, apparatus, and method are disclosed. A silicon substrate with a microfluidic system that receives a sample fluid and prepares an analyte solution received by a reservoir containing a sensing surface is electrically connected to a semiconductor device. The structure includes a component for receiving a sample fluid, a component for preparing the sample fluid, a CRISPR system for cleaving a reporter species when the sample fluid contains a target sequence, a sorting component for separating the cleaved reporter species from the sample fluid and the CRISPR products, a cavity for receiving an analyte solution containing the cleaved reporter species, and a sensing surface in the cavity. The sensing surface detects electrical signals induced by reaction events in the analyte solution.

Abstract: A structure, apparatus, and method are disclosed. A silicon substrate with a microfluidic system that receives a sample fluid and prepares an analyte solution received by a reservoir containing a sensing surface is electrically connected to a semiconductor device. The structure includes a component for receiving a sample fluid, a component for preparing the sample fluid, a CRISPR system for cleaving a reporter species when the sample fluid contains a target sequence, a sorting component for separating the cleaved reporter species from the sample fluid and the CRISPR products, a cavity for receiving an analyte solution containing the cleaved reporter species, and a sensing surface in the cavity. The sensing surface detects electrical signals induced by reaction events in the analyte solution.

Abstract: A microfluidic device comprising a channel within a substrate and a condenser or a hydrodynamic focusing chamber along the channel, configured to focus a fluid containing particles of a plurality of sizes. A negative angle deterministic lateral displacement (DLD) array is configured to receive the focused fluid and separate the particles in the focused fluid into three sizes ranges. The negative angle DLD array comprises a plurality of rows of pillars, wherein the rows of pillars are positioned to repeat a pattern every N rows with a shift of M columns, N and M are relatively coprime, and N is greater than 1.

Abstract: A method of forming a microfluidic device is disclosed. The method includes forming a first dielectric layer on a substrate, forming electrodes partially into the first dielectric layer, and forming a second dielectric layer on the electrodes. The method includes filling, with a metal material, two wells formed in the second dielectric layer such that the metal material is in direct contact with the electrodes. The method includes forming a third dielectric layer on the metal material and second dielectric layer. The method includes filling, with a structural material, a channel formed between the wells such that the structural material does not directly contact the electrodes. The method includes forming a fourth dielectric layer on the third dielectric layer and the structural material, extracting the structural material through at least one vent hole in the fourth dielectric layer, and forming a fifth dielectric layer on the fourth dielectric layer.

Abstract: An apparatus is provided. The apparatus may comprise a layer of a microfluidic chip. The layer may comprise a nanoscale deterministic lateral displacement (nanoDLD) array. The nanoDLD array may comprise a plurality of pillars arranged in a plurality of columns. Further, the nanoDLD array may separate particles from a purified fluidic sample associated with a bodily materials of an organism. A method for purifying at least one target particle from a sample by utilizing a sized-based separation is provided. The method may include detecting the at least one target particle associated with the sample, by utilizing at least one detector molecule in a nanoDLD array. The method may then include separating the detected at least one target particle and the at least one detector molecule from a bump fraction in the sample based on a size of the detected at least one target particle.

Abstract: A microfluidic device comprising a channel within a substrate and a condenser or a hydrodynamic focusing chamber along the channel, configured to focus a fluid containing particles of a plurality of sizes. A negative angle deterministic lateral displacement (DLD) array is configured to receive the focused fluid and separate the particles in the focused fluid into three sizes ranges. The negative angle DLD array comprises a plurality of rows of pillars, wherein the rows of pillars are positioned to repeat a pattern every N rows with a shift of M columns, N and M are relatively coprime, and N is greater than 1.

Abstract: An apparatus is provided. The apparatus may comprise a layer of a microfluidic chip. The layer may comprise a nanoscale deterministic lateral displacement (nanoDLD) array. The nanoDLD array may comprise a plurality of pillars arranged in a plurality of columns. Further, the nanoDLD array may separate particles from a purified fluidic sample associated with a bodily materials of an organism. A method for purifying at least one target particle from a sample by utilizing a sized-based separation is provided. The method may include detecting the at least one target particle associated with the sample, by utilizing at least one detector molecule in a nanoDLD array. The method may then include separating the detected at least one target particle and the at least one detector molecule from a bump fraction in the sample based on a size of the detected at least one target particle.

Abstract: A blade for mounting to a scraped surface heat exchanger drive shaft by pivotal connection with a mounting pin has a blade body having a first side and a second side, and a scraper edge and a hinge edge. At least one mounting hole extends through the blade body generally proximate at the hinge edge. An L-shaped locking track protrudes into the first set of the blade, having an entry track extending from the hinge edge and an intermediate track extending from the entry track to the mounting hole. An L-shaped locking track also protruding into the second side of the blade, has an entry track extending from the hinge edge of the blade and an intermediate track extending from the entry track to and past the mounting hole.

Abstract: Attachment apparatus and method for interlocking attachment of a scraper blade with a drive shaft of a scraped surface heat exchanger includes a blade having dual attachment beams and a central locking member, and at least one pin having dual fingers each for interlocking with a respective attachment beam.

Abstract: Attachment apparatus and method for interlocking attachment of a scraper blade with a drive shaft of a scraped surface heat exchanger includes a blade having dual attachment beams and a central locking member, and at least one pin having dual fingers each for interlocking with a respective attachment beam.

Abstract: A blade for mounting to a scraped surface heat exchanger drive shaft by pivotal connection with a mounting pin has a blade body having a first side and a second side, and a scraper edge and a hinge edge. At least one mounting hole extends through the blade body generally proximate at the hinge edge. An L-shaped locking track protrudes into the first set of the blade, having an entry track extending from the hinge edge and an intermediate track extending from the entry track to the mounting hole. An L-shaped locking track also protruding into the second side of the blade, has an entry track extending from the hinge edge of the blade and an intermediate track extending from the entry track to and past the mounting hole.

Abstract: Attachment apparatus and method for interlocking attachment of a scraper blade with a drive shaft of a scraped surface heat exchanger includes a blade having dual attachment beams and a central locking member, and at least one pin having dual fingers each for interlocking with a respective attachment beam.