Patents by Inventor Benjamin Isaacs

Benjamin Isaacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized liquid anti-RSV antibody formulations
    Publication number: 20070048332
    Abstract: The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.
    Type: Application
    Filed: February 24, 2006
    Publication date: March 1, 2007
    Inventors: Cynthia Oliver, Erica Shane, Benjamin Isaacs, Christian Allan, Stephen Chang
  • Pharmaceutical compositions of hydrophobic compounds
    Publication number: 20070031460
    Abstract: This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions.
    Type: Application
    Filed: October 11, 2006
    Publication date: February 8, 2007
    Inventors: John Augustine, Kaliappanadar Nellaiappan, Benjamin Isaacs, Indu Isaacs
  • STABILIZED LIQUID ANTI-RSV ANTIBODY FORMULATIONS
    Publication number: 20060034827
    Abstract: The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.
    Type: Application
    Filed: June 13, 2003
    Publication date: February 16, 2006
    Inventors: Cynthia Oliver, Erica Shane, Benjamin Isaacs, Christian Allan, Stephen Chang
  • Methods of enhancing solubility of compounds
    Publication number: 20050238673
    Abstract: This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions.
    Type: Application
    Filed: April 27, 2004
    Publication date: October 27, 2005
    Inventors: John Augustine, Kaliappanadar Nellaiappan, Benjamin Isaacs, Indu Isaacs