Patents by Inventor Benjamin J. Doranz

Benjamin J. Doranz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CLAUDIN 18.2 ANTIBODIES, METHODS OF MAKING THE SAME, AND USES THEREOF
    Publication number: 20230391885
    Abstract: Antibodies and compositions against Claudin 18.2 and uses thereof are provided herein.
    Type: Application
    Filed: June 1, 2023
    Publication date: December 7, 2023
    Inventors: Ross Stewart Chambers, Joseph Benjamin Rucker, Brad Alan Screnci, Trevor Andrew Barnes, Timothy Robin Phillips, Benjamin J. Doranz
  • Glucose transporter 4 antibodies, methods of making the same, and uses thereof
    Patent number: 11834497
    Abstract: Antibodies and compositions against GLUT4 and uses thereof are provided herein.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: December 5, 2023
    Assignee: INTEGRAL MOLECULAR, INC.
    Inventors: David F. Tucker, Kimberly-Anne Mattia, Christine R. Fisher, Benjamin J. Doranz, Joseph B. Rucker
  • Modified ebolavirus glycoproteins comprising mutations in the head and base domains that increase antibody cross-reactivity
    Patent number: 11135280
    Abstract: Provided herein are methods of incorporating substitutions of specified residues into a filovirus GP in order to increase immunogenicity and/or broaden the cross-reactivity of the protective immune response against other filovirus members. Also provided herein are mutant filovirus GPs comprising such substitutions.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: October 5, 2021
    Assignees: INTEGRATED BIOTHERAPEUTICS, INC., INTEGRAL MOLECULAR, INC.
    Inventors: Mohammad Javad Aman, Katie A. Howell, Edgar Davidson, Benjamin J. Doranz
  • GLUCOSE TRANSPORTER 4 ANTIBODIES, METHODS OF MAKING THE SAME, AND USES THEREOF
    Publication number: 20210238276
    Abstract: Antibodies and compositions against GLUT4 and uses thereof are provided herein.
    Type: Application
    Filed: April 30, 2019
    Publication date: August 5, 2021
    Inventors: David F. TUCKER, Kimberly-Anne MATTIA, Christine R. FISHER, Benjamin J. DORANZ, Joseph B. RUCKER
  • PAN FILOVIRUS VACCINE COMPOSITIONS AND METHODS OF MAKING
    Publication number: 20190381162
    Abstract: Provided herein are methods of incorporating substitutions of specified residues into a filovirus GP in order to increase immunogenicity and/or broaden the cross-reactivity of the protective immune response against other filovirus members. Also provided herein are mutant filovirus GPs comprising such substitutions.
    Type: Application
    Filed: March 27, 2017
    Publication date: December 19, 2019
    Inventors: Mohammad Javad AMAN, Katie A. HOWELL, Edgar DAVIDSON, Benjamin J. DORANZ
  • Lipoparticles comprising proteins, methods of making, and using the same
    Patent number: 9213027
    Abstract: The present invention relates to lipoparticles. The invention also relates to producing lipoparticles. The invention further relates to lipoparticles comprising a viral structural protein. The invention further relates to a lipoparticle comprising a membrane protein, and the lipoparticle can be attached to a sensor surface. The invention further relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: December 15, 2015
    Assignee: Integral Molecular, Inc.
    Inventors: Benjamin J. Doranz, Sharon Willis
  • Lipoparticles Comprising Proteins, Methods Of Making, And Using The Same
    Publication number: 20140135230
    Abstract: The present invention relates to lipoparticles. The invention also relates to producing lipoparticles. The invention further relates to lipoparticles comprising a viral structural protein. The invention further relates to a lipoparticle comprising a membrane protein, and the lipoparticle can be attached to a sensor surface. The invention further relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 15, 2014
    Applicant: Integral Molecular, Inc.
    Inventors: Benjamin J. Doranz, Sharon Willis
  • Lipoparticles comprising proteins, methods of making, and using the same
    Patent number: 8574590
    Abstract: The present invention relates to lipoparticles. The invention also relates to producing lipoparticles. The invention further relates to lipoparticles comprising a viral structural protein. The invention further relates to a lipoparticle comprising a membrane protein, and the lipoparticle can be attached to a sensor surface. The invention further relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: November 5, 2013
    Assignee: Integral Molecular, Inc.
    Inventors: Benjamin J. Doranz, Sharon Willis, Eric Ross, Tiffani Anne Greene
  • LIPOPARTICLES COMPRISING ION CHANNELS, METHODS OF MAKING AND USING THE SAME
    Publication number: 20130244222
    Abstract: The present invention relates to the use of lipoparticles, virus-like particles, and viruses. The present invention also relates to testing ion channel function and modulators of ion channels.
    Type: Application
    Filed: January 15, 2013
    Publication date: September 19, 2013
    Applicant: Integral Molecular, Inc.
    Inventor: Benjamin J. Doranz
  • Lipoparticles comprising ion channels, methods of making and using the same
    Patent number: 8377691
    Abstract: The present invention relates to the use of lipoparticles, virus-like particles, and viruses. The present invention also relates to testing ion channel function and modulators of ion channels.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: February 19, 2013
    Assignee: Integral Molecular, Inc.
    Inventor: Benjamin J. Doranz
  • Dengue Reporter Virus and Methods of Making and Using the Same
    Publication number: 20080318208
    Abstract: The present invention relates to the production and uses of Dengue virus replicons and Dengue reporter virus particles. The present invention relates to methods of identifying inhibitors of Dengue virus infection, inhibitors of Dengue virus replication, and inhibitors of Dengue virus assembly.
    Type: Application
    Filed: February 12, 2007
    Publication date: December 25, 2008
    Applicant: Integral Molecular, Inc.
    Inventors: Bridget Puffer, Benjamin J. Doranz
  • Elucidation of gene function
    Publication number: 20040132008
    Abstract: Articles and methods are provided for determining the function of genes in a rapid and cost effective manner. Nucleic acids are arrayed upon a substrate. In accordance with certain preferred embodiments, viable cells are subsequently caused to be bound to the substrate at the locations occupied by the nucleic acids. Subsequent transduction or transfection of the cells by the nucleic acids followed by continued vitality of the cells permits expression of the proteins encoded by the respected nucleic acids. Knowledge of the identity of the nucleic acids, at least as regards their locations on the substrate, permits determination of protein function thereof. Methods of creating and using such cell-arrays, and methods of reverse-transfection and reverse-transduction are featured.
    Type: Application
    Filed: January 27, 2004
    Publication date: July 8, 2004
    Inventor: Benjamin J Doranz